| STEUBEN COUNTY COMMUNITY FOUNDATION | Angola | T31Z Philanthropy, Voluntarism & Grantmaking Foundations | $11.7M | 1 |
| LITTLE SISTERS OF THE POOR OF | Indianapolis | E92Z Health Care | $11.6M | 9 |
| INDIANAPOLIS CULTURAL TRAIL INC | Indianapolis | S20 Community Improvement & Capacity Building | $11.5M | 2 |
| INDIANA SOYBEAN ALLIANCE INC | Indianapolis | — | $11.5M | 7 |
| INDIANA UNDERGROUND PLANT PROTECTION | Greenwood | — | $11.5M | 4 |
| COMMUNITY VENTURES IN LIVING LTD | Lafayette | S21Z Community Improvement & Capacity Building | $11.5M | 1 |
| TEACHERS TREASURES INC | Indianapolis | B90 Education | $11.5M | 1 |
| NATIONAL PRECAST CONCRETE ASSOCIATION | Carmel | — | $11.5M | 10 |
| NINETWELVE INSTITUTE INC | Zionsville | U02 Science & Technology | $11.4M | 0 |
| CENTRAL INDIANA CORPORATE | Indianapolis | S41 Community Improvement & Capacity Building | $11.4M | 12 |
| THE SMITH FAMILY FOUNDATION INC | Carmel | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $11.3M | 0 |
| LEWIS BROTHERS BAKERIES INC | Evansville | — | $11.3M | 0 |
| Sycamore Schools Inc | Indianapolis | B280 Education | $11.3M | 3 |
| ICI BENEFITS CONSORTIUM TRUST | Indianapolis | — | $11.3M | 0 |
| YOUNG MEN'S CHRISTIAN ASSOCIATION OF | Muncie | — | $11.3M | 4 |
| UNIVERSITY OF SOUTHERN INDIANA FOUNDATION INC | Evansville | B43I Education | $11.3M | 7 |
| ZETA TAU ALPHA FRATERNITY | Carmel | — | $11.3M | 1 |
| INTERNATIONAL ASSOCIATION OF SHEET METAL | Indianapolis | J40 Employment | $11.3M | 24 |
| KIDS' VOICE OF INDIANA INC | Indianapolis | P30 Human Services | $11.2M | 3 |
| SECOND HELPINGS INC | Indianapolis | K30 Food, Agriculture & Nutrition | $11.1M | 1 |
| INDIANA UNIVERSITY ALUMNI ASSOCIATION INC | Bloomington | — | $11.1M | 2 |
| GAYLOR ELECTRIC INC | Indianapolis | — | $11.1M | 0 |
| INTERNATIONAL BROTHERHOOD OF TEAMSTERS | Indianapolis | — | $11.1M | 12 |
| Community Action Program Inc | Covington | P20Z Human Services | $11.1M | 2 |
| IU MEDICAL GROUP FOUNDATION INC | Indianapolis | B114 Education | $11.1M | 7 |
| CUSTOM ELECTRONIC DESIGN & INSTALLATION | Fishers | — | $11M | 9 |
| JUDD LEIGHTON FOUNDATION INC | South Bend | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $11M | 5 |
| Indianapolis Downtown Inc | Indianapolis | S200 Community Improvement & Capacity Building | $11M | 3 |
| PACE COMMUNITY ACTION AGENCY INC | Vincennes | P200 Human Services | $10.9M | 3 |
| DEMOTTE CHRISTIAN SCHOOL | Demotte | B200 Education | $10.9M | 0 |
| SOUTHERN INDIANA RESOURCE SOLUTIONS INC | Boonville | J30Z Employment | $10.9M | 2 |
| CASS COUNTY COMMUNITY FOUNDATION INC | Logansport | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $10.8M | 1 |
| RAUCH INC | New Albany | P820 Human Services | $10.8M | 4 |
| TURNING POINT ACTION INC | Indianapolis | — | $10.7M | 2 |
| Cultivate Culinary School | South Bend | J22 Employment | $10.7M | 1 |
| OPTIONS SCHOOLS INC | Noblesville | B29 Education | $10.7M | 2 |
| EdChoice Inc | Indianapolis | B90 Education | $10.6M | 9 |
| EVANSVILLE PROTESTANT HOME INC | Evansville | P750 Human Services | $10.6M | 6 |
| EVANSVILLE RESCUE MISSION INC | Evansville | — | $10.6M | 1 |
| HARRISON COUNTY COMMUNITY | Corydon | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $10.6M | 2 |
| SOUTHFIELD VILLAGE INC | South Bend | P750 Human Services | $10.6M | 8 |
| PORTER COUNTY GOVERNMENT CHARITABLE NONPROFIT FOUNDATION INC | Valparaiso | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $10.5M | 0 |
| COMMUNITY FOUNDATION OF SOUTHERN | New Albany | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $10.5M | 1 |
| OVERDOSE LIFELINE INC | Indianapolis | F20 Mental Health & Crisis Intervention | $10.5M | 2 |
| LOCAL UNION NO 103 INTERNATIONAL UNION | Indianapolis | — | $10.4M | 10 |
| THE PATH SCHOOL INC | Indianapolis | B29 Education | $10.4M | 2 |
| OHIO VALLEY OPPORTUNITIES INC | Madison | P200 Human Services | $10.4M | 2 |
| Pulaski Health Foundation INC | Francesville | E122 Health Care | $10.4M | 4 |
| INDIANA MATH & SCIENCE ACADEMY NORTH | Indianapolis | B29 Education | $10.4M | 1 |
| MEDICAL PRACTICE CONSORTIUM TRUST | Indianapolis | Y43 Mutual & Membership Benefit | $10.4M | 0 |
