| PIKE SCHOOL CORPORATION INC A/K/A PARKLANE ACADEMY | McComb | B20 Education | $7.1M | 1 |
| AMITE COUNTY MEDICAL SERVICES INC | Liberty | E300 Health Care | $7.1M | 8 |
| LAMAR SCHOOL FOUNDATION | Meridian | B24 Education | $7M | 0 |
| AMBITION PREPARATORY CHARTER SCHOOL | Jackson | B29 Education | $6.8M | 2 |
| NORTH CENTRAL PLANNING AND DEVELOPM DISTRICT INC | Winona | P200 Human Services | $6.8M | 3 |
| My Brother's Keeper Inc | Ridgeland | G058 Diseases, Disorders & Medical Disciplines | $6.7M | 5 |
| CATHOLIC CHARITIES INC | Jackson | P20Z Human Services | $6.6M | 5 |
| BREVARD FAMILY FOUNDATION | Tupelo | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $6.4M | 0 |
| TUPELO CHILDREN'S MANSION INC | Tupelo | — | $6.4M | 2 |
| RUSH CARE INC | Meridian | E24 Health Care | $6.3M | 7 |
| MAGNOLIA HEIGHTS SCHOOL INC | Senatobia | B242 Education | $6.3M | 1 |
| MISSISSIPPI MUSEUM OF ART INC | Jackson | A510 Arts, Culture & Humanities | $6.3M | 1 |
| THE JOSEPH C BANCROFT CHARITABLE AND EDUCATIONAL FUND | McComb | T900 Philanthropy, Voluntarism & Grantmaking Foundations | $6.2M | 4 |
| DEEP SOUTH TODAY | Ridgeland | A30 Arts, Culture & Humanities | $6.1M | 7 |
| COPIAH EDUCATIONAL FOUNDATION INC | Gallman | — | $6.1M | 1 |
| PROGRESS COMMUNITY WATER ASSOCIATION | Purvis | — | $6.1M | 0 |
| BROOKHAVEN ACADEMY EDUCATIONAL FOUNDATION INCORPORATED | Brookhaven | B242 Education | $6.1M | 0 |
| SUNFLOWER-HUMPHREYS CTYS PROG INC | Indianola | S200 Community Improvement & Capacity Building | $6M | 1 |
| RENAISSANCE COMMUNITY LOAN FUND | Gulfport | M20 Public Safety, Disaster Preparedness & Relief | $5.9M | 5 |
| WILLOWOOD DEVELOPMENTAL CENTER INC | Jackson | — | $5.9M | 1 |
| FIVE COUNTY CHILD DEVELOPMENT INC | Prentiss | B21 Education | $5.9M | 0 |
| SHAW EDUCATIONAL FOUNDATION INC | Cleveland | B20 Education | $5.9M | 0 |
| WOODWARD HINES EDUCATION FOUNDATION | Jackson | B820 Education | $5.9M | 19 |
| CENTRAL MISSISSIPPI HEALTH SERVICES | Jackson | — | $5.9M | 6 |
| REGENTS SCHOOL OF OXFORD INC | Oxford | B24 Education | $5.9M | 3 |
| Prairie Opportunity Inc | Starkville | S200 Community Improvement & Capacity Building | $5.8M | 2 |
| ALUMNI ASSOCIATION OF THE UNIVERSITY OF MISSISSIPPI | Oxford | B84Z Education | $5.8M | 1 |
| TUPELO CHRISTIAN PREPARATORY SCHOOL | Belden | B24Z Education | $5.8M | 1 |
| PALMER HOME FOR CHILDREN | Lake Cormorant | P730 Human Services | $5.8M | 4 |
| NETWORK OF INTERNATIONAL CHRISTIAN SCHOOLS/OASIS INTERNATIONAL SCHOOLS | Southaven | X20Z Religion-Related | $5.7M | 4 |
| RIVER HILLS CLUB OF JACKSON | Jackson | — | $5.7M | 1 |
| SPRINGBOARD TO OPPORTUNITIES | Jackson | P20 Human Services | $5.6M | 1 |
| PARK PLACE CHRISTIAN ACADEMY INC | Pearl | B24 Education | $5.6M | 0 |
| HABITAT FOR HUMANITY OF THE MISSISSIPPI GULF COAST | Gulfport | L250 Housing & Shelter | $5.5M | 2 |
| ANDERSON PHYSICIAN ALLIANCE INC | Meridian | E31 Health Care | $5.5M | 11 |
| OAKWOOD FOUNDATION CHARITABLE TRUST | Tupelo | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $5.4M | 0 |
| MISSISSIPPI STATE UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION | Mississippi State | — | $5.4M | 0 |
| Lift Inc | Tupelo | — | $5.3M | 2 |
| EAST LOWNDES WATER ASSOCIATION | Columbus | — | $5.3M | 5 |
| COMMUNITY DEVELOPMENT FOUNDATION | Tupelo | — | $5.3M | 0 |
| CHILDRENS ADVOCACY CENTERS OF MISSISSIPPI | Jackson | P01 Human Services | $5.3M | 1 |
| ALCORN STATE UNIVERSITY FOUNDATION INC | Lorman | B43I Education | $5.2M | 0 |
| WASHINGTON COUNTY DAY SCHOOL ASSOCIATION INC | Greenviile | B20 Education | $5.2M | 3 |
| MISSISSIPPI HIGH SCHOOL ACTIVITIES ASSOCIATION INC | Clinton | L41D Housing & Shelter | $5.2M | 3 |
| HOPE VILLAGE FOR CHILDREN INC | Meridian | P43 Human Services | $5.2M | 0 |
| THE BOYS AND GIRLS CLUBS OF THE GULF COAST INC | Gulfport | — | $5.1M | 1 |
| DELTA MEDICAL FOUNDATION | Marks | E32 Health Care | $5.1M | 3 |
| MISSISSIPPI CHILDREN'S HOME SERVICES INC | Jackson | P193 Human Services | $5.1M | 11 |
| COLUMBUS EDUCATIONAL FOUNDATION INC | Columbus | B24Z Education | $5.1M | 1 |
| Mississippi Center For Legal Services Corporation | Hattiesburg | — | $5.1M | 3 |
