| NEW COVENANT ACADEMY | Springfield | — | $7.9M | 3 |
| CARONDELET LONG-TERM CARE FACILITIES INC | St Louis | G9B Diseases, Disorders & Medical Disciplines | $7.9M | 13 |
| GREATER JOPLIN AREA EMERGENCY MEDICAL SERVICES SYSTEM INC | Joplin | — | $7.9M | 1 |
| SACRED HEART REHABILITATION INSTITUTE INC | St Louis | E50Z Health Care | $7.9M | 14 |
| FIREFLY SCIENTISTS FOUNDATION | St Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.8M | 0 |
| Delta Center for Independent Living | Saint Peters | P80Z Human Services | $7.8M | 1 |
| THE JEREMIAH 924 FOUNDATION | Springfield | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.8M | 0 |
| MISSOURI WESTERN STATE UNIVERSITY FOUNDATION INC | St Joseph | — | $7.8M | 2 |
| ST LOUIS SCIENCE CENTER FOUNDATION | St Louis | U20 Science & Technology | $7.8M | 7 |
| Mid America Teen Challenge Training Center Inc | Cape Girardeau | F22 Mental Health & Crisis Intervention | $7.8M | 1 |
| COLUMBIA INDEPENDENT SCHOOL INC | Columbia | B20 Education | $7.8M | 1 |
| THE OASIS INSTITUTE | St Ann | P810 Human Services | $7.7M | 6 |
| Centene Foundation | St Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.7M | 0 |
| Heartland Foundation | St Joseph | E120 Health Care | $7.7M | 9 |
| HILLCREST PLATTE COUNTY | Riverside | L41 Housing & Shelter | $7.7M | 0 |
| MID-AMERICA ARTS ALLIANCE | Kansas City | A260 Arts, Culture & Humanities | $7.7M | 4 |
| CONSERVATION EMPLOYEES' CREDIT UNION | Jefferson City | — | $7.7M | 1 |
| ALEXIAN BROTHERS MEDICAL GROUP SPECIALTY CARE | St Louis | E60 Health Care | $7.6M | 6 |
| Provident Inc | St Louis | F300 Mental Health & Crisis Intervention | $7.6M | 7 |
| BASS PRO SHOPS & CABELAS OUTDOOR FUND | Springfield | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $7.6M | 0 |
| TRUMAN MEDICAL CENTER PROFESSIONAL AND GENERAL LIABILITY SELF INSURANCE TRUST | Kansas City | E80 Health Care | $7.6M | 6 |
| THE RESEARCH FOUNDATION | Kansas City | E110 Health Care | $7.6M | 2 |
| COMMUNITY ACTION AGENCY OF GREATER KANSAS CITY | Kansas City | P60Z Human Services | $7.6M | 4 |
| SEMO ALLIANCE FOR DISABILITY INDEPENDENCE INC | Cape Girardeau | P82Z Human Services | $7.6M | 1 |
| ALTCAP | Kansas City | S20 Community Improvement & Capacity Building | $7.6M | 7 |
| BUILDERS INTERNATIONAL FOUNDATION | Ozark | P20 Human Services | $7.6M | 0 |
| MISSOURI PHARMACY ASSOCIATION | Jefferson City | — | $7.5M | 1 |
| LYRIC OPERA OF KANSAS CITY INC | Kansas City | A6A0 Arts, Culture & Humanities | $7.5M | 2 |
| JEWISH FAMILY SERVICES OF ST LOUIS | Saint Louis | P30Z Human Services | $7.5M | 4 |
| First Missouri Credit Union | St Louis | — | $7.5M | 5 |
| YOUNG AT HEART RESOURCES | Cameron | — | $7.5M | 2 |
| MISSOURI ASSOCIATION OF REALTORS | Columbia | — | $7.5M | 3 |
| CITIZENS OF THE WORLD CHARTER SCHOOL-KANSAS CITY | Kansas City | B29 Education | $7.5M | 1 |
| WILLIAM A BADGER FOUNDATION | Saint Louis | T900 Philanthropy, Voluntarism & Grantmaking Foundations | $7.5M | 1 |
| EVERGY INC RETIRED EMPLOYEES HEALTH AND WELFARE FUND | Kansas City | — | $7.5M | 1 |
| SALLY ANN FIRESTONE FOUNDATION | Kansas City | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.5M | 0 |
| UNLIMITED OPPORTUNITIES INC | Boonville | A50Z Arts, Culture & Humanities | $7.4M | 1 |
| TEAMSTERS MEDICARE TRUST FOR RETIRED EMPLOYEES | St Louis | — | $7.4M | 0 |
| CASCO AREA WORKSHOP INC | Harrisonville | — | $7.4M | 0 |
| EXPLORE BRANSON TOURISM | Branson | S30 Community Improvement & Capacity Building | $7.4M | 6 |
| The Lesley Waldheim Charitable Foundation | Saint Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.4M | 0 |
| EMMANUEL FAMILY AND CHILD DEVELOPMENT CENTER & EMERGENCY SHELTER FOR CHILDR | Kansas City | B99 Education | $7.4M | 1 |
| MID-AMERICA CARPENTERS REGIONAL BENEFITS | St Louis | J19 Employment | $7.3M | 0 |
| DIERBERG FAMILY FOUNDATION | Clayton | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $7.3M | 0 |
| CHURCHILL CENTER AND SCHOOL FOR LEARNING DISABILITIES | Town Country | — | $7.3M | 7 |
| LIVING WORD CHRISTIAN SCHOOL | Ofallon | B20Z Education | $7.3M | 2 |
| HOPE HOUSE INC | Lees Summit | P430 Human Services | $7.3M | 4 |
| UPWARD SMILES INC | Festus | E30 Health Care | $7.3M | 3 |
| National Association of Basketball Coaches | Kansas City | — | $7.3M | 6 |
| Medical Plaza Imaging Associates LLC | Kansas City | E21 Health Care | $7.3M | 4 |
