| SWI Industrial Solutions Inc | Springfield | J330 Employment | $4.4M | 1 |
| CALVARY UNIVERSITY | Kansas City | — | $4.4M | 5 |
| ASSOCIATED GENERAL CONTRACTORS OF MISSOURI | St Louis | — | $4.4M | 5 |
| COMMUNITY FOUNDATION OF CENTRAL MO | Columbia | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $4.4M | 1 |
| THE CHILD ADVOCACY CENTER OF NORTHEAST MISSOURI INC | Wentzville | I720 Crime & Legal-Related | $4.4M | 2 |
| LUTHERAN FAMILY AND CHILDREN'S SERVICES FOUNDATION | St Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.4M | 0 |
| PIPEFITTERS ASSOCIATION LOCAL UNION 533 | Kansas City | — | $4.4M | 16 |
| GRAPHIC COMMUNICATIONS CONFERENCE OF THE INTERNATIONAL BROTHERHOOD | Independence | — | $4.4M | 0 |
| FAMILY ADVOCACY AND COMMUNITY TRAINING INC | St Charles | — | $4.4M | 1 |
| MISSOURI PARTNERSHIP | St Louis | S41 Community Improvement & Capacity Building | $4.4M | 3 |
| Living With Purpose Inc | Saint Louis | L40 Housing & Shelter | $4.4M | 6 |
| MISSOURI ASSOCIATION OF PROSECUTING ATTORNEYS | Jefferson City | S41 Community Improvement & Capacity Building | $4.4M | 1 |
| SPRINGFIELD CONVENTION AND VISITORS BUREAU INC | Springfield | — | $4.4M | 1 |
| OUR LADY OF MERCY COUNTRY HOME | Liberty | — | $4.4M | 1 |
| ST ANDREWS RESOURCES FOR SENIORS SYSTEM | St Louis | P80 Human Services | $4.4M | 8 |
| CENTRAL MISSOURI HUMANE SOCIETY | Columbia | D200 Animal-Related | $4.4M | 1 |
| SAINT LOUIS SYMPHONY ENDOWMENT TRUST | Saint Louis | A69 Arts, Culture & Humanities | $4.3M | 0 |
| Jesus Real Inc | Springfield | X99 Religion-Related | $4.3M | 0 |
| FLORISSANT VALLEY SHELTERED WORKSHOP INC | Hazelwood | J330 Employment | $4.3M | 1 |
| KANBE'S MARKETS | Kansas City | K31 Food, Agriculture & Nutrition | $4.3M | 1 |
| Presence Care Transformation Corporation | St Louis | E210 Health Care | $4.3M | 10 |
| FIRST FRUITS OF ZION INC | Marshfield | X99Z Religion-Related | $4.3M | 5 |
| COMMUNITY HEALTH COMMISSION OF MISSOURI | St Louis | E60 Health Care | $4.3M | 4 |
| SAUL MIROWITZ JEWISH SCHOOL | St Louis | B20Z Education | $4.3M | 3 |
| PLUMBERS AND PIPEFITTERS HEALTH & WELFARE FUND | St Joseph | — | $4.3M | 0 |
| Elsberry Missouri Health Care Center Inc | Elsberry | E91Z Health Care | $4.3M | 1 |
| INTERNATIONAL ASSOCIATION OF ADMINISTRATIVE PROFESSIONALS | Kansas City | — | $4.3M | 4 |
| TREASURE LAKE RV RESORT CAMPING CLUB INC | Branson | N50 Recreation & Sports | $4.3M | 1 |
| POWELL GARDENS INC | Kingsville | — | $4.2M | 2 |
| THE SOSLAND FOUNDATION | Kansas City | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.2M | 1 |
| CSD CREDIT UNION | Kansas City | — | $4.2M | 1 |
| INTERFAITH COMMUNITY SERVICES INC | Saint Joseph | P200 Human Services | $4.2M | 2 |
| Robert J Trulaske Jr Family Foundation | St Louis | T120 Philanthropy, Voluntarism & Grantmaking Foundations | $4.2M | 1 |
| UNLEASHING POTENTIAL | Saint Louis | P280 Human Services | $4.2M | 2 |
| CAPE GIRARDEAU COMMUNITY SHELTERED WORKSHOP INC | Cape Girardeau | J33Z Employment | $4.2M | 1 |
| UKRAINE PARTNERSHIP FOUNDATION | Chesterfield | B12 Education | $4.2M | 0 |
| GINGERBREAD HOUSE INC | Rolla | P73Z Human Services | $4.2M | 1 |
| SETON ORAL & MAXILLOFACIAL SURGERY | St Louis | E30 Health Care | $4.2M | 6 |
| LITERACY KANSAS CITY | Kansas City | — | $4.2M | 2 |
| SMITH MABEL E TR FBO MASTER'S UNIV | Saint Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.2M | 1 |
| SPRINGFIELD VICTORY MISSION INC | Springfield | P600 Human Services | $4.2M | 1 |
| INTERNATIONAL ASSOCIATION OF HEAT & FROST INSULATORS & ALLIED LOCAL 27 | Independence | — | $4.2M | 11 |
| Jack F and Glenna Y Wylie Charitable Fdn Tr | Kansas City | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.2M | 1 |
| Scripted Healthcare System | Kansas City | E01 Health Care | $4.1M | 3 |
| OPTIMIST INTERNATIONAL | Saint Louis | — | $4.1M | 5 |
| REGIONAL BUSINESS COUNCIL | Saint Louis | S20 Community Improvement & Capacity Building | $4.1M | 3 |
| LOYOLA ACADEMY OF ST LOUIS | St Louis | B20 Education | $4.1M | 1 |
| MISSOURI RURAL WATER ASSOCIATION | Ashland | — | $4.1M | 2 |
| RIO VISTA FOUNDATION | St Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.1M | 0 |
| PINE VIEW MANOR INC | Stanberry | E91Z Health Care | $4.1M | 2 |
