| The Big South Conference Inc | Charlotte | — | $6.1M | 2 |
| High Point Country Club Inc | High Point | N50 Recreation & Sports | $6.1M | 6 |
| SOUTHMOUNTAIN CHILDREN AND FAMILY SERVICES | Morganton | P70Z Human Services | $6.1M | 4 |
| GUIL-RAND FIRE PROTECTIVE ASSOCIATION INC | Archdale | M24Z Public Safety, Disaster Preparedness & Relief | $6.1M | 0 |
| AJ FLETCHER FOUNDATION | Raleigh | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $6.1M | 1 |
| PERSON COUNTY GROUP HOMES INC | Roxboro | P73Z Human Services | $6.1M | 1 |
| St Luke's Physician Network Inc | Columbus | E32 Health Care | $6.1M | 5 |
| University Health Systems of Eastern Carolina Foundation Inc | Greenville | E70 Health Care | $6M | 1 |
| LSA Elms at Tanglewood Inc | Salisbury | — | $6M | 6 |
| THE W DUKE KIMBRELL FAMILY FOUNDATION CO JULIA B SINGH | Gastonia | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $6M | 1 |
| Charmeck Family Justice Center Inc co Safe Alliance | Charlotte | I71 Crime & Legal-Related | $6M | 0 |
| NORTH CAROLINA SCHOOL OF SCIENCE AND MATHEMATICS FOUNDATION | Durham | — | $6M | 3 |
| UNITED HEALTH CENTERS | Winstonsalem | E20 Health Care | $6M | 9 |
| Next Generation Academy | Greensboro | B24 Education | $6M | 0 |
| UNCW STUDENT AID ASSOCIATION INC | Wilmington | — | $6M | 1 |
| United Faith Christian Academy | Charlotte | B20 Education | $6M | 0 |
| ANGLO-AMERICAN CHARITABLE FOUNDATION LTD | Smithfield | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $6M | 0 |
| MACON CITIZENS HABILITIES INC | Franklin | — | $6M | 2 |
| THE ENOLA GROUP | Morganton | — | $6M | 1 |
| ROBESON COUNTY PARTNERSHIP FOR CHILDREN | Lumberton | B012 Education | $6M | 1 |
| CENTER FOR HEALTHY LIVING INC | Charlotte | P70 Human Services | $6M | 1 |
| Youngsville Academy Charter School Inc | Youngsville | B24 Education | $6M | 0 |
| HAYDEN-HARMAN FOUNDATION | Burlington | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $6M | 4 |
| BLUE RIDGE HEALTHCARE SYSTEM INC | Morganton | E21 Health Care | $6M | 3 |
| Telra Institute Inc | Charlotte | B29 Education | $5.9M | 1 |
| NC UNITED METHODIST CAMP & RETREAT MINISTRIES INC | Garner | O99 Youth Development | $5.9M | 2 |
| BOYS CLUB OF WAKE COUNTY INC | Raleigh | O210 Youth Development | $5.9M | 3 |
| SUMMERFIELD FIRE DISTRICT INC | Summerfield | M24 Public Safety, Disaster Preparedness & Relief | $5.9M | 1 |
| SNOWBIRD OUTFITTERS INC | Andrews | O55 Youth Development | $5.9M | 3 |
| NATIONAL HUMANITIES CENTER | Research Triangle Park | A70 Arts, Culture & Humanities | $5.9M | 6 |
| The Mountain Retreat & Learning Center Inc | Highlands | T192 Philanthropy, Voluntarism & Grantmaking Foundations | $5.9M | 3 |
| BLADEN'S BLOOMIN' AGRI-INDUSTRIAL INC | Elizabethtown | S30 Community Improvement & Capacity Building | $5.9M | 1 |
| ENKA-CANDLER FIRE AND RESCUE DEPARTMENT INC | Candler | M24 Public Safety, Disaster Preparedness & Relief | $5.9M | 2 |
| The New Dimensions School Inc | Morganton | B29 Education | $5.9M | 3 |
| SOUTHERN COALITION FOR SOCIAL JUSTICE | Durham | I80 Crime & Legal-Related | $5.9M | 6 |
| EAST LINCOLN FIRE DEPARTMENT STATION #3 | Stanley | M24 Public Safety, Disaster Preparedness & Relief | $5.9M | 2 |
| CALDWELL HOSPICE AND PALLIATIVE CARE INC DBA AMOREM | Lenoir | P74Z Human Services | $5.8M | 0 |
| THE CEMALA FOUNDATION INC | Greensboro | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.8M | 2 |
| HABITAT FOR HUMANITY ORANGE COUNTY NC INC | Chapel Hill | — | $5.8M | 2 |
| Rosedale Health and Wellness Pc | Huntersville | — | $5.8M | 1 |
| NEW GARDEN FRIENDS SCHOOL INC | Greensboro | — | $5.8M | 2 |
| Institute for the Development of Young Leaders | Durham | Y99 Mutual & Membership Benefit | $5.8M | 0 |
| EL FUTURO INC | Durham | F32 Mental Health & Crisis Intervention | $5.8M | 5 |
| PINECROFT-SEDGEFIELD FIRE DISTRICT INC | Greensboro | M24 Public Safety, Disaster Preparedness & Relief | $5.8M | 1 |
| LIBERTAS BOILING SPRINGS | Forest City | B20 Education | $5.8M | 1 |
| PARTNERS IN LEARNING CHILD DEVELOPMENT AND FAMILY RESOURCE CENTER | Salisbury | P33 Human Services | $5.8M | 1 |
| SOIL HEALTH INSTITUTE | Morrisville | C30 Environment | $5.8M | 9 |
| Carolina Pregnancy Care Fellowship | Winstonsalem | E400 Health Care | $5.8M | 1 |
| The Healing Place of New Hanover County Inc | Wilmington | F20 Mental Health & Crisis Intervention | $5.8M | 1 |
| SURGICAL REVIEW CORPORATION | Raleigh | E05 Health Care | $5.8M | 11 |
