| TULSA HABITAT FOR HUMANITY INC | Tulsa | L20Z Housing & Shelter | $20.1M | 6 |
| COMMUNITY HEALTH CENTERS INC | Oklahoma City | E32Z Health Care | $20.1M | 13 |
| OKLAHOMA HUMANE SOCIETY | Oklahoma City | D20 Animal-Related | $20M | 3 |
| COMMUNITY ACTION AGENCY OF OKLAHOMA CITY & OKLAHOMA/CANADIAN COUNTIES | Oklahoma City | P20Z Human Services | $19.9M | 2 |
| CROSSROADS YOUTH & FAMILY SERVICES INC | Norman | P30 Human Services | $19.9M | 3 |
| SOUTHERN HILLS COUNTRY CLUB | Tulsa | — | $19.8M | 7 |
| RECORDS JOHNSTON FAMILY FOUNDATION | Oklahoma City | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $19.8M | 0 |
| United Way of Central Oklahoma Inc | Oklahoma City | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $19.4M | 4 |
| OKLAHOMA PROPERTY AND CASUALTY INSURANCE GUARANTY ASSOCIATION | Oklahoma City | — | $19.4M | 0 |
| KIRKPATRICK FAMILY AFFILIATED FUND OF OCCF INC | Oklahoma City | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $19.3M | 4 |
| BOKF FOUNDATION | Tulsa | T110 Philanthropy, Voluntarism & Grantmaking Foundations | $18.9M | 1 |
| GROUND WATER PROTECTION | Oklahoma City | — | $18.8M | 4 |
| FAMILY HEALTH CENTER OF SOUTHERN OKLAHOMA INC | Tishomingo | E30 Health Care | $18.6M | 10 |
| MERCY HOSPITAL KINGFISHER INC | Kingfisher | — | $18.3M | 17 |
| GREAT SALT PLAINS HEALTH CENTER INC | Cherokee | E32 Health Care | $18.3M | 11 |
| TULSA FIREFIGHTERS HEALTH & WELFARE PLAN | Jay | Y44 Mutual & Membership Benefit | $18M | 0 |
| OKLAHOMA BAPTIST HOMES FOR CHILDREN INC | Oklahoma City | P730 Human Services | $17.7M | 7 |
| OKLAHOMA PUBLIC SCHOOL RESOURCE CENTER | Oklahoma City | B90 Education | $17.6M | 7 |
| JOHN 316 MISSION | Tulsa | P850 Human Services | $17.6M | 1 |
| PLUMBERS AND PIPEFITTERS LOCAL UNION NO 344 | Oklahoma City | — | $17.4M | 3 |
| OKLAHOMA EDUCATORS CREDIT UNION | Oklahoma City | — | $17.3M | 5 |
| The HA & Mary K Chapman Foundation | Tulsa | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $17.2M | 2 |
| OSTEOPATHIC MEDICAL EDUCATION CONSORTIUM OF OKLAHOMA DBA OMECO | Tulsa | B122 Education | $17.2M | 0 |
| OKLAHOMA LIFE AND HEALTH INSURANCE GUARANTY ASSOCIATION | Oklahoma City | — | $17.1M | 0 |
| TULSA HONOR ACADEMY INC | Tulsa | B29 Education | $17.1M | 1 |
| Hearts for Hearing Foundation | Oklahoma City | P87 Human Services | $16.8M | 7 |
| GREATER OKLAHOMA CITY CHAMBER OF COMMERCE INC | Oklahoma City | — | $16.8M | 9 |
| GLENN FOUNDATION FOR MEDICAL RESEARCH INC | Edmond | H99Z Medical Research | $16.8M | 1 |
| HOPE IS ALIVE MINISTRIES INC | Oklahoma City | F22 Mental Health & Crisis Intervention | $16.6M | 4 |
| TULSA CHRISTIAN EDUCATION CORPORATION | Tulsa | B21Z Education | $16.4M | 2 |
| HOME OF HOPE INC | Vinita | P820 Human Services | $16.3M | 0 |
| Laureate Institute for Brain Research Inc | Tulsa | V23Z Social Science | $16.1M | 8 |
| ST SIMEON'S EPISCOPAL HOME INC | Tulsa | P750 Human Services | $16M | 6 |
| A NEW LEAF INC | Owasso | — | $15.9M | 1 |
| PEOPLE INC OF SEQUOYAH COUNTY | Sallisaw | P82Z Human Services | $15.8M | 0 |
| NATIONAL REINING HORSE ASSOCIATION | Oklahoma City | K26 Food, Agriculture & Nutrition | $15.5M | 6 |
| The Center of Family Love | Okarche | P82Z Human Services | $15.5M | 1 |
| OKLAHOMA CHRISTIAN SCHOOLS INC | Edmond | — | $15.4M | 1 |
| THE FRANCIS AND KATHLEEN ROONEY FOUNDATION | Tulsa | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $15.3M | 0 |
| McCalls Community Homes Inc | Ada | L20 Housing & Shelter | $15.3M | 3 |
| AMERICAN ASSOCIATION OF PETROLEUM GEOLOGISTS | Tulsa | — | $15.1M | 4 |
| ROD BAKER MINISTRIES INC | Tulsa | X90 Religion-Related | $15M | 4 |
| PIPELINERS LOCAL UNION 798 | Tulsa | — | $14.9M | 37 |
| COMMUNITY HEALTH CONNECTION INC | Tulsa | E60 Health Care | $14.8M | 11 |
| COMMUNITY ACTION RESOURCE AND DEVELOPMEN | Claremore | — | $14.8M | 2 |
| COMMUNITY ACTION DEVELOPMENT CORPORATION | Frederick | — | $14.7M | 2 |
| Southern Plains Tribal Health Board Foundation | Oklahoma City | G99 Diseases, Disorders & Medical Disciplines | $14.6M | 6 |
| LEGACY TITLE HOLDING CORPORATION | Durant | S47 Community Improvement & Capacity Building | $14.5M | 0 |
| EAST CENTRAL UNIVERSITY FOUNDATION INC | Ada | — | $14.4M | 4 |
| CATHOLIC CHARITIES OF THE ARCHDIOCESE OF OKLAHOMA CITY INC | Oklahoma City | — | $14.4M | 2 |
