| SIOUX FALLS PUBLIC SCHOOLS EDUCATION | Sioux Falls | B113 Education | $768k | 1 |
| SOUTHERN BLACK HILLS WATER SYSTEM | Hot Springs | W80 Public & Societal Benefit | $766k | 1 |
| OAYE LUTA OKOLAKICIYE | Rapid City | F21 Mental Health & Crisis Intervention | $765k | 1 |
| Black Hills Utility Holdings Inc | Rapid City | Y43 Mutual & Membership Benefit | $758k | 0 |
| MUSEUM ALLIANCE OF RAPID CITY INC | Rapid City | A540 Arts, Culture & Humanities | $757k | 1 |
| ALL ABOUT U ADOPTIONS INC | Sioux Falls | P31 Human Services | $755k | 1 |
| Journey On Inc | Rapid City | O50 Youth Development | $755k | 0 |
| SD Deaf Resource & Outreach Programs | Rapid City | P87 Human Services | $755k | 2 |
| SOUTH DAKOTA GOLF ASSOCIATION | Sioux Falls | — | $753k | 1 |
| WAMBLI SKA SOCIETY | Box Elder | A20 Arts, Culture & Humanities | $747k | 4 |
| FRIENDS OF THE CHILDREN - HE SAPA | Rapid City | G99 Diseases, Disorders & Medical Disciplines | $746k | 1 |
| New Hope Uganda Ministries Inc | Belle Fourche | Q330 International, Foreign Affairs & National Security | $738k | 2 |
| THE JAMES AND ELOISE ELMEN FOUNDATION | Sioux Falls | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $738k | 1 |
| RIVER CITY DOMESTIC VIOLENCE CENTER | Yankton | P43 Human Services | $732k | 1 |
| HE SAPA OTIPI INC | Rapid City | P20 Human Services | $727k | 2 |
| ASSOCIATED GENERAL CONTRACTORS OF SOUTH DAKOTA INC - BUILDING CHAPTER | Sioux Falls | — | $727k | 0 |
| BLACK HILLS AREA COUNCIL INC | Rapid City | — | $726k | 1 |
| SOUTH DAKOTA SOIL HEALTH COALITION | Pierre | C30 Environment | $723k | 0 |
| Sunset Memorial Gardens of Aberdeen Inc | Aberdeen | — | $723k | 1 |
| CENTRAL GLOBAL VISION FUND INC | Milbank | Q113 International, Foreign Affairs & National Security | $719k | 0 |
| MEADOW CREEK GOLF CLUB | Brookings | — | $719k | 0 |
| THE RLB CHARITABLE FOUNDATION | Sioux Falls | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $718k | 0 |
| FUND FOR ADVANCEMENT OF MEDICAL | Sioux Falls | E12 Health Care | $712k | 9 |
| Servants Heart Foundation | Custer | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $712k | 0 |
| FOUNDATION SEED STOCKS DIVISION | Brookings | — | $711k | 0 |
| BLACK HILLS ROUNDUP | Belle Fourche | — | $711k | 0 |
| Sioux Falls Thrive Inc | Sioux Falls | P05 Human Services | $710k | 1 |
| Aberdeen Area Chamber of Commerce | Aberdeen | — | $706k | 2 |
| SOUTH DAKOTA HABITAT CONSERVATION | Pierre | C30 Environment | $706k | 0 |
| WARNER VOLUNTEER FIRE DEPARTMENT | Warner | M24 Public Safety, Disaster Preparedness & Relief | $700k | 0 |
| HARTFORD AREA DEVELOPMENT | Hartford | S31 Community Improvement & Capacity Building | $700k | 0 |
| Mobridge Regional Healthcare Foundation | Mobridge | L80Z Housing & Shelter | $699k | 2 |
| BYRON BIBLE CAMP | Huron | N20Z Recreation & Sports | $697k | 1 |
| MOVE THE MOUNTAIN LEADERSHIP CENTER | Rapid City | W707 Public & Societal Benefit | $694k | 1 |
| SOUTH DAKOTA PARENT CONNECTION | Sioux Falls | P41Z Human Services | $693k | 1 |
| YANKTON AREA SENIOR CITIZEN | Yankton | — | $693k | 1 |
| Yelduz Shriners | Aberdeen | Y40Z Mutual & Membership Benefit | $690k | 1 |
| RAPID CITY SPORTS COMMISSION | Rapid City | — | $688k | 1 |
| SOUTH DAKOTA BAR FOUNDATION | Pierre | I128 Crime & Legal-Related | $688k | 0 |
| Storybook Island Inc | Rapid City | — | $688k | 0 |
| SOUTH DAKOTA DENTAL ASSOCIATION | Pierre | — | $686k | 1 |
| Brookings Ice Skating Association Inc | Brookings | — | $677k | 0 |
| HEALING THE CULTURE | Rapid City | P50 Human Services | $676k | 1 |
| WATERTOWN CHRISTIAN SCHOOL | Watertown | — | $676k | 0 |
| THE TIPI RAISERS | Mission | P20 Human Services | $674k | 1 |
| South Dakota Soybean Association | Sioux Falls | — | $673k | 1 |
| WESTERN RESOURCES FOR INDEPEND | Rapid City | P80Z Human Services | $671k | 1 |
| DAKOTA LAKES RESEARCH FARM | Pierre | — | $665k | 0 |
| NECOG Development Corporation | Aberdeen | W60 Public & Societal Benefit | $665k | 7 |
| YANKTON YOUTH SOCCER ASSOCIATION | Yankton | — | $658k | 0 |
