| BATON ROUGE CHRISTIAN EDUCATION FOUNDATION INC | Baton Rouge | — | $22.6M | 6 |
| UNION GENERAL HOSPITAL | Farmerville | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $22.2M | 8 |
| UNIVERSITY OF HOLY CROSS | New Orleans | — | $22.1M | 4 |
| FRENCH AND MONTESSORI EDUCATION INC DBA AUDUBON CHARTER SCHOOL | New Orleans | B24 Education | $22M | 2 |
| GULF COAST HOUSING PARTNERSHIP INC | New Orleans | P20 Human Services | $21.8M | 0 |
| PARKING FACILITIES CORPORATION | New Orleans | S11 Community Improvement & Capacity Building | $21.8M | 0 |
| CADDO COMMUNITY ACTION AGENCY INC | Shreveport | P200 Human Services | $21.7M | 6 |
| NEW ORLEANS SUPER BOWL HOST COMMITTEE | Metairie | S41 Community Improvement & Capacity Building | $21.5M | 0 |
| REGINA COELI CHILD DEVELOPMENT CENTER | Robert | B22Z Education | $21.4M | 3 |
| UNIVERSITY FACILITIES INC | Hammond | L400 Housing & Shelter | $21.3M | 2 |
| THE FOOD BANK OF CENTRAL LOUISIANA | Alexandria | — | $21.3M | 0 |
| BELLE CHASSE ACADEMY INC | Belle Chasse | B90 Education | $21M | 5 |
| SOUTHERN UNIVERTY SYSTEM | Baton Rouge | B43I Education | $21M | 0 |
| WESTSIDE HABILITATION CENTER INC | Alexandria | P82Z Human Services | $21M | 0 |
| WORLD WAR II THEATRE INC | New Orleans | A11 Arts, Culture & Humanities | $20.5M | 4 |
| HOLY ANGELS RESIDENTIAL FACILITY I | Shreveport | P73 Human Services | $20.3M | 5 |
| LOUISIANA ACHIEVEMENT CHARTER ACADEMIES INC | Baton Rouge | B19 Education | $20.3M | 0 |
| The Glen Retirement System | Shreveport | P750 Human Services | $20.2M | 5 |
| Giving Hope Inc | New Orleans | P99 Human Services | $20.1M | 1 |
| BBR Schools Inc | Baton Rouge | B29 Education | $20.1M | 1 |
| ATHLOS ACADEMY OF JEFFERSON | Terrytown | B12 Education | $20M | 0 |
| LEGACY OF EXCELLENCE INC | New Orleans | B29 Education | $19.8M | 2 |
| NEW SCHOOLS FOR NEW ORLEANS INC | New Orleans | B19 Education | $19.8M | 7 |
| CITY PARK CONSERVANCY | New Orleans | N32 Recreation & Sports | $19.7M | 8 |
| LSU HEALTH SCIENCES FOUNDATION IN SHREVEPORT | Shreveport | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $19.4M | 3 |
| SHREVEPORT CHARTER FOUNDATION INC | Shreveport | B20 Education | $19.3M | 0 |
| FOREKIDS FOUNDATIONS INC DBA ZURICH CLASSIC OF NEW ORLEANS | Avondale | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $19.1M | 2 |
| WARREN EASTON HIGH SCHOOL FOUNDATION INC DBA WARREN EASTON CHARTER SCHOOL | New Orleans | B29 Education | $18.9M | 1 |
| HC Drew Estate | Lake Charles | — | $18.8M | 3 |
| GULF COAST TEACHING FAMILY SERVICESINC D/B/A GULF COAST SOCIAL SERVICES | Metairie | — | $18.7M | 3 |
| SCHOOL FOOD AND NUTRITION SERVICES OF NEW ORLEANS INC | Metairie | — | $18.5M | 1 |
| THE COMMUNITY FOUNDATION OF NORTH LOUISIANA | Shreveport | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $18.5M | 2 |
| HOSPICE OF ACADIANA INC | Lafayette | P74Z Human Services | $18.5M | 8 |
| THE ARC CADDO-BOSSIER | Shreveport | P82Z Human Services | $18.5M | 1 |
| ACADIANA CONCERN FOR AIDS RELIEF EDUCATION AND SUPPORT INC | Lafayette | G81Z Diseases, Disorders & Medical Disciplines | $18.4M | 1 |
| NOCHI REAL ESTATE INC | New Orleans | S47 Community Improvement & Capacity Building | $18.3M | 0 |
| SOUTHEAST LOUISIANA LEGAL SERVICES CORP | Hammond | I80Z Crime & Legal-Related | $18.2M | 1 |
| NORTHLAKE CHRISTIAN SCHOOL | Covington | — | $18.1M | 4 |
| INTERNATIONAL SCHOOL OF LOUISIANA | New Orleans | B20 Education | $18M | 4 |
| THE LOUISE S MCGEHEE SCHOOL | New Orleans | — | $17.9M | 2 |
| SHREVEPORT CHARTER SCHOOL INC | Shreveport | B29 Education | $17.9M | 1 |
| BAPTIST COMMUNITY MINISTRIES | New Orleans | B50 Education | $17.9M | 5 |
| Central South Carpenters Regional Council | Metairie | — | $17.4M | 11 |
| WOLDENBERG VILLAGE | New Orleans | L220 Housing & Shelter | $17.4M | 8 |
| NEW ORLEANS MILITARY AND MARITIME ACADEMY INC | New Orleans | B29 Education | $17.4M | 2 |
| LSU HEALTH FOUNDATION NEW ORLEANS | New Orleans | E110 Health Care | $17.4M | 6 |
| CLEAN GULF ASSOCIATES INC | New Orleans | S41 Community Improvement & Capacity Building | $17.2M | 2 |
| LAMBETH HOUSE INC | New Orleans | P750 Human Services | $17.1M | 0 |
| THE WATER INSTITUTE OF THE GULF | Baton Rouge | C32 Environment | $17.1M | 9 |
| EXCELTH INC | New Orleans | E30Z Health Care | $16.9M | 6 |
