| PROVIDENCE CLASSICAL ACADEMY INC | Bossier City | B200 Education | $16.3M | 1 |
| PACE GREATER NEW ORLEANS | New Orleans | — | $16.2M | 6 |
| ADVOCATES FOR ACADEMIC EXCELLENCE IN EDUCATION INC | New Orleans | B29 Education | $15.8M | 4 |
| University of New Orleans Foundation | New Orleans | B11 Education | $15.8M | 1 |
| MAGNOLIA COMMUNITY SERVICES INC | Jefferson | — | $15.7M | 3 |
| BLUE CROSS & BLUE SHIELD OF LOUISIANA FOUNDATION | Baton Rouge | M20 Public Safety, Disaster Preparedness & Relief | $15.7M | 1 |
| OLLIE STEELE BURDEN MANOR INC | Baton Rouge | E91Z Health Care | $15.7M | 9 |
| LYCEE FRANCAIS DE LA NOUVELLE ORLEANS | New Orleans | B29 Education | $15.6M | 1 |
| POYDRAS HOME | New Orleans | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $15.6M | 1 |
| BRICOLAGE ACADEMY | New Orleans | B20 Education | $15.6M | 2 |
| CLOVER NOLA INC | New Orleans | P200 Human Services | $15.5M | 7 |
| Southwest Louisiana Credit Union | Lake Charles | — | $15.5M | 7 |
| Primary Health Services Center Inc | Monroe | E30 Health Care | $15.4M | 15 |
| OCF MEDICAL FACILITIES II INC | New Orleans | S47 Community Improvement & Capacity Building | $15.2M | 3 |
| NEW ORLEANS COUNTRY CLUB | New Orleans | — | $15.1M | 11 |
| CATHOLIC CHARITIES OF THE DIOCESE OF BATON ROUGE INC | Baton Rouge | P200 Human Services | $15.1M | 2 |
| EASTER SEALS LOUISIANA INC | New Orleans | — | $15M | 2 |
| MCNEESE STATE UNIVERSITY FOUNDATION | Lake Charles | B110 Education | $15M | 0 |
| LOUISIANA KEY ACADEMY | Baton Rouge | B29 Education | $15M | 0 |
| BAYOU SUGAR GROWERS INC | Carencro | K20 Food, Agriculture & Nutrition | $14.7M | 0 |
| PELICAN EDUCATIONAL FOUNDATION INC | Baton Rouge | B200 Education | $14.6M | 1 |
| METAIRIE COUNTRY CLUB | Metairie | — | $14.5M | 6 |
| DARBONNE WOODS CHARTER SCHOOL INC | Farmerville | B21 Education | $14.5M | 0 |
| OPELOUSAS GENERAL HEALTH SYSTEM PHYSICIAN PRACTICES INC | Opelousas | E30 Health Care | $14.4M | 0 |
| ASCENT HEALTH INC | Monroe | F32 Mental Health & Crisis Intervention | $14.3M | 5 |
| TERREBONNE ARC | Houma | P82Z Human Services | $14.3M | 2 |
| COUNTRY CLUB OF LOUISIANA | Baton Rouge | — | $14.2M | 7 |
| AUDUBON RETIREMENT VILLAGE INC | New Orleans | P75 Human Services | $14.2M | 6 |
| LOUISIANA NATIONAL GUARD FOUNDATION | New Orleans | W30 Public & Societal Benefit | $14.2M | 1 |
| CHILDRENS HOSPITAL MEDICAL PRACTICE CORP | New Orleans | E30Z Health Care | $14M | 7 |
| JEFFERSON RISE INC | Harvey | B25 Education | $13.9M | 2 |
| QUAD AREA COMMUNITY ACTION AGENCY INC | Hammond | P20Z Human Services | $13.9M | 3 |
| Provident Commonwealth Education Resources Inc | Baton Rouge | L20 Housing & Shelter | $13.8M | 3 |
| SON OF A SAINT | New Orleans | O50 Youth Development | $13.6M | 2 |
| LIFE 4 PAWS | Napoleonville | D20 Animal-Related | $13.4M | 3 |
| BATON ROUGE COUNTRY CLUBINC | Baton Rouge | — | $13.4M | 9 |
| GOODWILL INDUSTRIES OF NORTH LA INC | Shreveport | J32Z Employment | $13.3M | 4 |
| FOOD BANK OF NORTHEAST LOUISIANA INC | Monroe | P20 Human Services | $13.2M | 1 |
| OUR LADY OF THE LAKE ASSUMPTION COMMUNITY HOSPITAL | Baton Rouge | — | $13.2M | 9 |
| Innis Community Health Center Inc | Innis | E20 Health Care | $13.2M | 6 |
| PINNACLE FAMILY HEALTH INC | West Monroe | G81Z Diseases, Disorders & Medical Disciplines | $13.2M | 7 |
| Grambling High Foundation dba Lincoln Preparatory School | Grambling | B11 Education | $13.1M | 1 |
| Caresouth Cares Foundation | Baton Rouge | B82 Education | $13.1M | 0 |
| UNIVERSITY OF NEW ORLEANS RESEARCH AND TECHNOLOGY FOUNDATION INC | New Orleans | E110 Health Care | $13M | 2 |
| MULTI-FAITH RETIREMENT SERVICES | Shreveport | — | $13M | 2 |
| Citizens Committee for Education dba Homer A Plessy Community School | New Orleans | B20 Education | $12.9M | 1 |
| GENTILLY CARNIVAL CLUB | Jefferson | N52 Recreation & Sports | $12.8M | 0 |
| THE FRIENDS OF KING SCHOOL | New Orleans | B29 Education | $12.8M | 5 |
| LOUISIANA PUBLIC HEALTH INSTITUTE | New Orleans | E30 Health Care | $12.8M | 9 |
| UNIVERSITY OF LOUISIANA AT MONROE FOUNDATION | Monroe | B110 Education | $12.7M | 0 |
