| UNITED WAY OF SOUTHEAST LOUISIANA | New Orleans | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $12.5M | 8 |
| REGIONAL NUTRITION ASSISTANCE | Lafayette | K400 Food, Agriculture & Nutrition | $12.4M | 1 |
| Westminster Christian Academy | Opelousas | B200 Education | $12.4M | 2 |
| BROADWAY SERVICES INC | New Orleans | P70 Human Services | $12.4M | 5 |
| UNIVERSITY OF LOUISIANA MONROE | Monroe | B80 Education | $12.3M | 0 |
| Mercy Medical LLC | Hodge | E20 Health Care | $12.2M | 1 |
| INNOVATIVE STUDENT FACILITIES INC | Ruston | L99 Housing & Shelter | $12.2M | 0 |
| ACADIANA LEGAL SERVICE CORPORATION | Lafayette | I80Z Crime & Legal-Related | $12.1M | 6 |
| LOUISIANA SOCIETY FOR THE PREVENTION OF | New Orleans | D200 Animal-Related | $12.1M | 5 |
| VICTORIA HEALTHCARE RESOURCES INC | Pleasant Hill | E60 Health Care | $12M | 0 |
| OUR LADY OF THE LAKE ASSUMPTION | Baton Rouge | — | $11.9M | 13 |
| Citizens Committee for Education dba | New Orleans | B20 Education | $11.8M | 1 |
| LARCINC | Lafayette | P82Z Human Services | $11.7M | 1 |
| LAFOURCHE ARC | Thibodaux | P82Z Human Services | $11.6M | 2 |
| Nicholls State University Foundation | Thibodaux | B42I Education | $11.6M | 1 |
| VANS KIDDIE CAREINC | New Iberia | P300 Human Services | $11.6M | 2 |
| LOUISIANA KEY ACADEMY | Baton Rouge | B29 Education | $11.6M | 0 |
| Provident Commonwealth Education Resources II Inc | Baton Rouge | L20 Housing & Shelter | $11.6M | 3 |
| REDESIGN SCHOOLS LOUISIANA | Baton Rouge | B02 Education | $11.5M | 2 |
| ST MARGARETS FOUNDATION | New Orleans | E22 Health Care | $11.5M | 1 |
| Louisiana Coalition Against Domestic | Baton Rouge | — | $11.5M | 1 |
| EVERGREEN PRESBYTERIAN MINISTRIES OF TEXAS INC | Haughton | P73I Human Services | $11.3M | 4 |
| CHIMP HAVEN INC | Keithville | D310 Animal-Related | $11.3M | 2 |
| LSU HEALTH FOUNDATION NEW ORLEANS | New Orleans | E110 Health Care | $11.2M | 6 |
| ARISE SCHOOLS | New Orleans | B24 Education | $11.2M | 1 |
| EAST RIDGE COUNTRY CLUB | Shreveport | — | $11.1M | 6 |
| JEFFERSON RISE INC | Harvey | B25 Education | $11.1M | 2 |
| NEW ORLEANS MUSEUM OF ART | New Orleans | A510 Arts, Culture & Humanities | $11.1M | 5 |
| NEW ORLEANS JEWISH COMMUNITY CENTER | New Orleans | P280 Human Services | $11M | 7 |
| LOUISIANA THOROUGHBRED BREEDERS | New Orleans | — | $11M | 14 |
| PARTICULAR COUNCIL OF ST VINCENT DE | Baton Rouge | — | $10.9M | 1 |
| LASALLE COMMUNITY ACTION | Harrisonburg | — | $10.8M | 0 |
| THE COUNCIL FOR QUALITY EDUCATION DBA | New Orleans | B29 Education | $10.7M | 3 |
| PRIME TIME FAMILY READING | New Orleans | B90 Education | $10.7M | 1 |
| LOUISIANA FARM BUREAU FEDERATION | Baton Rouge | — | $10.7M | 28 |
| ST MARGARET'S DAUGHTERS HOME | New Orleans | — | $10.7M | 1 |
| NEW ORLEANS MISSION INC | New Orleans | — | $10.6M | 1 |
| URBAN LEAGUE OF LOUISIANA | New Orleans | P22Z Human Services | $10.6M | 3 |
| STATE CHARTERED CREDIT UNIONS IN LOUISIANA | Baton Rouge | — | $10.6M | 4 |
| Boys Town Louisiana Inc | New Orleans | P70 Human Services | $10.6M | 3 |
| NORTHSHORE COMMUNITY FOUNDATION | Covington | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $10.6M | 1 |
| ST MARY COMMUNITY ACTION AGENCY INC | Franklin | — | $10.6M | 3 |
| INSPIRE CHARTER ACADEMY INC | East Baton Rouge | B29 Education | $10.5M | 0 |
| COMMCARE LOUISIANA | Mandeville | E91 Health Care | $10.5M | 1 |
| Southern Center for | Monroe | R200 Civil Rights, Social Action & Advocacy | $10.4M | 0 |
| CHILDRENS COALITION FOR NORTHEAST LOUISIANA | Monroe | I72 Crime & Legal-Related | $10.3M | 2 |
| NEW ORLEANS FAMILY JUSTICE ALLIANCE | New Orleans | P40 Human Services | $10.3M | 2 |
| DELHI CHARTER SCHOOL | Delhi | B29 Education | $10.3M | 1 |
| CHRISTIAN SCHOOLS INC | River Ridge | — | $10.2M | 5 |
| WILLWOODS COMMUNITY | Metairie | L22 Housing & Shelter | $10.2M | 3 |
