| SUMTER UNITED MINISTRIES | Sumter | — | $1.3M | 1 |
| SOUTH CAROLINA HUMANITIES COUNCIL INC | Columbia | A26Z Arts, Culture & Humanities | $1.3M | 1 |
| GEORGETOWN COUNTY ALCOHOL AND DRUG ABUSE COMMISSION | Georgetown | F20Z Mental Health & Crisis Intervention | $1.3M | 1 |
| PALMETTO COUNCIL INC BOY SCOUTS OF AMERICA 549 | Spartanburg | O41Z Youth Development | $1.3M | 1 |
| The Reams Foundation Inc | Charleston | Z99Z Unknown | $1.3M | 0 |
| CENTRAL CAROLINA REALTORS ASSOCIATION | Columbia | — | $1.3M | 2 |
| PROJECT HOST INC | Greenville | — | $1.3M | 1 |
| FORT MILL PREPARATORY COOPERATION PRESCHOOL | Fort Mill | A01 Arts, Culture & Humanities | $1.3M | 1 |
| BEAUFORT JASPER HOUSING TRUST | Beaufort | S30 Community Improvement & Capacity Building | $1.3M | 0 |
| NEW VISION RESEARCH | Mt Pleasant | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $1.3M | 1 |
| SC FUTURE MAKERS FKA SOUTH CAROLINA MANUF EDUCATION FOUND | Columbia | B80 Education | $1.3M | 1 |
| THE CARE HOUSE OF THE PEE DEE INC | Florence | B92 Education | $1.3M | 1 |
| The CART Fund Inc | Sumter | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $1.3M | 0 |
| HOUSING DEVELOPMENT CORPORATION OF ROCK HILL | Rock Hill | L20Z Housing & Shelter | $1.3M | 0 |
| SC LAUNCH INC | Columbia | S11 Community Improvement & Capacity Building | $1.3M | 3 |
| PINE RIDGE CLUB INC | Edgefield | — | $1.3M | 0 |
| GENERATIONS GROUP HOMES OF GREENVILLE INC | Simpsonville | I440 Crime & Legal-Related | $1.3M | 0 |
| Lowcountry Local First | Charleston | S41 Community Improvement & Capacity Building | $1.3M | 1 |
| MEALS ON WHEELS OF HORRY AND GEORGETOWN COUNTY INC | Myrtle Beach | K36 Food, Agriculture & Nutrition | $1.3M | 1 |
| LAURENS COUNTY SAFE HOMES | Clinton | — | $1.3M | 1 |
| Partners In Agriculture Inc | Greenville | P20 Human Services | $1.3M | 0 |
| MANUFACTURED HOUSING INSTITUTE OF S | Columbia | — | $1.3M | 1 |
| HIS HOUSE OF COLUMBIA INC | West Columbia | — | $1.3M | 3 |
| FAMILY JUSTICE CENTER OF GEORGETOWN AND HORRY COUNTIES | Georgetown | P50 Human Services | $1.3M | 1 |
| SC BATTLEGROUND PRESERVATION TRUST | Charleston | — | $1.3M | 1 |
| CONESTEE FOUNDATION INC | Conestee | C27 Environment | $1.3M | 1 |
| Newberry County Family YMCA | Newberry | P27 Human Services | $1.3M | 1 |
| Auntie Karen Foundation | Columbia | O50 Youth Development | $1.3M | 1 |
| LEXINGTON COUNTY FIRST STEPS TO SCHOOL READINESS PARTNERSHIP | Greenwood | B012 Education | $1.3M | 0 |
| FANNY PACK FOUNDATION | Daniel Island | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $1.3M | 0 |
| Daniel-Mickel Foundation | Greenville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $1.3M | 5 |
| CHILDREN'S RECOVERY CENTER INC | Myrtle Beach | P622 Human Services | $1.3M | 0 |
| DAVENANT INSTITUTE INC | Landrum | X99 Religion-Related | $1.3M | 0 |
| CLEMSON COMMUNITY CARE INCORPORATED | Clemson | K31 Food, Agriculture & Nutrition | $1.3M | 1 |
| ETA GAMMA CHAPTER OF CHI OMEGA HOUSING CORPORATION | Columbia | — | $1.3M | 0 |
| BENNETT GALLEGOS | Rock Hill | X20 Religion-Related | $1.3M | 0 |
| PROVIDENT BUSINESS FINANCIAL SERVICES INC | West Columbia | S43 Community Improvement & Capacity Building | $1.3M | 3 |
| BEAUFORT COUNTY OPEN LAND TRUST | Beaufort | C340 Environment | $1.3M | 1 |
| THE CHARLES LEA CENTER FOUNDATION INC | Spartanburg | — | $1.3M | 1 |
| HEJAZ SHRINERS | Greenville | — | $1.3M | 0 |
| HENRY & SYLVIA YASCHIK FOUNDATION INC | Charleston | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $1.3M | 2 |
| CANCER ASSOCIATION OF SPARTANBURG & CHEROKEE COUNTIES INC | Spartanburg | — | $1.2M | 1 |
| RUBICON INC | Hartsville | — | $1.2M | 0 |
| SAINT FRANCES ANIMAL CENTER | Georgetown | D200 Animal-Related | $1.2M | 1 |
| TEACH MY PEOPLE | Pawleys Island | X21 Religion-Related | $1.2M | 0 |
| FRIENDS OF THE ANIMAL SHELTER INC | Aiken | D20 Animal-Related | $1.2M | 0 |
| LOWCOUNTRY ORPHAN RELIEF | N Charleston | P30 Human Services | $1.2M | 0 |
| ARTS CENTER OF KERSHAW COUNTY INC | Camden | A61Z Arts, Culture & Humanities | $1.2M | 1 |
| CHARLESTON DEFENSE CONTRACTORS ASSOCIATION | Mount Pleasant | S41 Community Improvement & Capacity Building | $1.2M | 0 |
| FIRST LIGHT | Anderson | F42Z Mental Health & Crisis Intervention | $1.2M | 1 |
