| HOPEFUL RESTORATION GROUP INC | Little River | P99 Human Services | $522k | 0 |
| Spartanburg Youth Soccer Club Inc | Spartanburg | N64 Recreation & Sports | $522k | 0 |
| SHIELD MINISTRIES | North Charleston | P20 Human Services | $522k | 2 |
| SOUTH CAROLINA RECREATION & PARKS | Lexington | N30C Recreation & Sports | $520k | 1 |
| SC DELTA HOUSING CORPORATION | Blythewood | B83 Education | $519k | 0 |
| THE SHARK CLUB INC | Murrells Inlet | B94 Education | $519k | 0 |
| CHRISTMASVILLE | Rock Hill | A27 Arts, Culture & Humanities | $519k | 0 |
| BABCOCK CENTER FOUNDATIONINC | West Columbia | P82I Human Services | $518k | 1 |
| SC Crime Stoppers Council | Walhalla | I20 Crime & Legal-Related | $518k | 0 |
| AHEPA 284 INC | Columbia | L20Z Housing & Shelter | $518k | 0 |
| ROPER MOUNTAIN SCIENCE | Greenville | — | $518k | 0 |
| ALSTON WILKES FOUNDATION | Columbia | — | $518k | 0 |
| NURTURING CENTER INC | Columbia | P620 Human Services | $517k | 1 |
| SOUTH CAROLINA ASSOCIATION OF PUBLIC | Columbia | B990 Education | $517k | 1 |
| JOHNSONVILLE RESCUE SQUAD AND AMBULANCE | Johnsonville | E62Z Health Care | $516k | 3 |
| UPSTATE MEDIATION CENTER | Greenville | I51 Crime & Legal-Related | $515k | 1 |
| CHAPIN AMERICAN LEGION POST 193 | Chapin | — | $514k | 0 |
| THE RAMAK FOUNDATION | Charleston | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $514k | 0 |
| SERVANTS FOR SIGHT | Greenville | G41 Diseases, Disorders & Medical Disciplines | $514k | 1 |
| SUMMERVILLE DREAM INC | Summerville | A80 Arts, Culture & Humanities | $513k | 1 |
| CHEROKEE HISTORICAL & PRESERVATION SOCIETY INC | Gaffney | B99 Education | $513k | 1 |
| THE PRIESTER FOUNDATION | Greenville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $512k | 0 |
| PAWLEYS ISLAND FESTIVAL OF MUSIC | Pawleys Island | A67Z Arts, Culture & Humanities | $512k | 2 |
| SOUTHERN ASSOCIATION OF STUDENT | North Myrtle Beach | S41Z Community Improvement & Capacity Building | $512k | 0 |
| The ARK of SC | Summerville | G83 Diseases, Disorders & Medical Disciplines | $512k | 0 |
| UU WORLD OF CHILDREN | Greenville | B110 Education | $512k | 1 |
| Florence & Gordon Holland Family Foundation | Hilton Head Island | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $511k | 0 |
| MENTAL HEALTH AMERICA OF | Bluffton | F80 Mental Health & Crisis Intervention | $511k | 0 |
| THE AMERICAN LEGION INDIAN LAND POST 250 | Indian Land | — | $511k | 0 |
| THE MUSEUM ASSOCIATION INC | Greenville | A12 Arts, Culture & Humanities | $510k | 0 |
| REDUX CONTEMPORARY ART CENTER | Charleston | A40 Arts, Culture & Humanities | $509k | 0 |
| THE FAMILY RESOURCE CENTER | Camden | — | $508k | 0 |
| JEHOVAH MISSIONARY BAPTIST CHURCH | Sumter | P33Z Human Services | $507k | 0 |
| MEALS ON WHEELS | Hilton Head | — | $506k | 0 |
| Pendleton Historic Foundation | Pendleton | — | $506k | 1 |
| Seth M Milliken Foundation Inc | Spartanburg | — | $506k | 0 |
| TRINITY METHODIST CHURCH APARTMENT INC | Camden | L20Z Housing & Shelter | $505k | 0 |
| AMERICAN LEGION SUMTER POST 15 | Sumter | — | $505k | 0 |
| UNITED WAY OF SUMTER CLARENDON | Sumter | — | $505k | 0 |
| J L MANN ATHLETIC BOOSTER CLUB INC | Greenville | B112 Education | $504k | 0 |
| LIGHTKEEPERS MARINA INC | Little River | N50 Recreation & Sports | $504k | 0 |
| HILTON HEAD AREA HOSPITALITY ASSOCIATION | Hilton Head Island | — | $504k | 1 |
| CHILD ADVOCACY CENTER OF AIKEN COUNTY | Aiken | I72 Crime & Legal-Related | $503k | 1 |
| GOOD NEIGHBOR CUPBOARD | Anderson | K31 Food, Agriculture & Nutrition | $502k | 0 |
| Huguenot Society of South Carolina | Charleston | X210 Religion-Related | $502k | 0 |
| EDISTO HABITAT FOR HUMANITY | Orangeburg | — | $500k | 0 |
| ASHUTOSH THE LOVE OF SHIVA INC | Elgin | E30 Health Care | $500k | 0 |
| Ambassadors of Love Inc | Travelers Rest | P60 Human Services | $500k | 0 |
| A Place For Us Ministries Inc | Greenwood | P42 Human Services | $500k | 0 |
| TYGER RIVER CHILDRENS CENTER INC | Moore | B20 Education | $499k | 1 |
