| DISTRICT ELDERLY HOUSING DEVELOPMENT CORPORATION | West Columbia | L21Z Housing & Shelter | $583k | 0 |
| AMAZING GRACE PARK CLEMENTA PINCKNEY MEMORIAL FOUNDATION | Marion | N32 Recreation & Sports | $582k | 0 |
| Charleston Apartment Association | Charleston | — | $582k | 0 |
| CONGAREE VISTA GUILD | Columbia | S41 Community Improvement & Capacity Building | $581k | 1 |
| FORT MILL UNITED INC | Fort Mill | N64 Recreation & Sports | $581k | 2 |
| UNION COUNTY COUNCIL ON AGING | Union | P81Z Human Services | $581k | 0 |
| FACES AND VOICES OF RECOVERY TRI-COUNTY INC | Lake Wylie | P20 Human Services | $580k | 3 |
| DILLON COUNTY FIRST STEPS TO SCHOOL READINESS PARTNERSHIP | Greenwood | B122 Education | $579k | 1 |
| FAMILY PROMISE OF BEAUFORT COUNTY | Bluffton | P20 Human Services | $579k | 1 |
| VEAZEY FAMILY FOUNDATION | Charleston | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $579k | 0 |
| BRICE-SANDERS FOUNDATION | Greenville | X20 Religion-Related | $579k | 1 |
| Go Love | York | Q32 International, Foreign Affairs & National Security | $578k | 0 |
| KAPPA ALPHA ORDER RHO CHAPTER | Columbia | — | $577k | 0 |
| Columbia Sailing Club | Columbia | — | $577k | 0 |
| WORLD YOUTH GROUP | Westminster | X20 Religion-Related | $576k | 0 |
| BIRTHMATTERS | Spartanburg | — | $576k | 1 |
| DICK HORNE FOUNDATION | Orangeburg | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $575k | 3 |
| THE CHANGE CENTER INC | North Myrtle Beach | S20 Community Improvement & Capacity Building | $574k | 1 |
| COASTAL SCHOOL MINISTRIES INC | Myrtle Beach | B99 Education | $574k | 0 |
| REFUGE INTERNATIONAL INC | Gilbert | Q71 International, Foreign Affairs & National Security | $574k | 0 |
| SPANISH WELLS POA | Hilton Head Island | — | $573k | 0 |
| LANGSTON FOUNDATION INC | Greenville | B21 Education | $573k | 0 |
| Spartanburg Area Housing Corporation | Spartanburg | L20 Housing & Shelter | $572k | 0 |
| TECHNICAL COLLEGE OF THE LOWCOUNTRY FOUNDATION INC | Beaufort | B41I Education | $571k | 1 |
| CENTER FOR COMMUNITY SERVICES | Simpsonville | P20Z Human Services | $571k | 0 |
| TRI-COUNTY SPEAKS | Charleston | — | $570k | 0 |
| CHARLESTON HOPE | Charleston | B90 Education | $570k | 1 |
| Tri County Regional Development Corporation | Georgetown | L20 Housing & Shelter | $569k | 0 |
| ART LEAGUE OF HILTON HEAD INC | Hilton Head Island | — | $569k | 0 |
| UNITED WAY OF SUMTER CLARENDON AND LEE COUNTIES INC | Sumter | — | $568k | 0 |
| GREATER GREER CHAMBER OF COMMERCE | Greer | — | $567k | 1 |
| HERITAGE ACADEMY SC | St Helena Island | B29 Education | $567k | 1 |
| ORANGEBURG COUNTY FIRST STEPS TO SCHOOL READINESS PARTNERSHIP | Greenwood | B012 Education | $566k | 1 |
| HOUSE OF HOPE INTERNATIONAL | Fountain Inn | M20 Public Safety, Disaster Preparedness & Relief | $566k | 1 |
| REAL CHAMPIONS INC | Ridgeland | O51 Youth Development | $565k | 0 |
| Ambassadors of Love Inc | Travelers Rest | P60 Human Services | $564k | 0 |
| TRINITY FOUNDATION | Myrtle Beach | X111 Religion-Related | $563k | 0 |
| SOUTH CAROLINA COUNCIL ON ECONOMIC EDUCATION | Columbia | — | $563k | 1 |
| Islamic Society of Greenville | Greenville | — | $563k | 0 |
| JAMES E CLYBURN SCHOLARSHIP AND RESEARCH FOUNDATION | Columbia | B82Z Education | $562k | 1 |
| AMELIA VILLAGE HOUSING CORPORATION | Columbia | — | $561k | 0 |
| UNITED WAY OF LAURENS COUNTY INC | Clinton | — | $559k | 1 |
| Aiken Polo Club Inc | Aiken | N6XZ Recreation & Sports | $559k | 0 |
| SIGAL MUSIC MUSEUM | Greenville | A68 Arts, Culture & Humanities | $559k | 0 |
| BRAIN INJURY ASSOCIATION OF SC | Chapin | E12 Health Care | $559k | 1 |
| ELDERLY HOUSING INC D/B/A/ THE CANTERBURY HOUSE EAST | Charleston | L81 Housing & Shelter | $559k | 0 |
| HOME BUILDERS ASSOCIATION OF HILTON HEAD | Hilton Head Island | — | $558k | 0 |
| KEY CHANGES THERAPY FOUNDATION INC | Columbia | E11 Health Care | $558k | 0 |
| POE MILL ACHIEVEMENT CENTER | Greenville | B80 Education | $558k | 1 |
| BEECH ISLAND VOLUNTEER FIRE DEPARTM | Beech Island | M24 Public Safety, Disaster Preparedness & Relief | $557k | 0 |
