| WYOMING WEATHERIZATION SERVICES | Worland | L81 Housing & Shelter | $4.3M | 2 |
| Evanston Child Development Center | Evanston | — | $4.3M | 1 |
| GOLDEN HEART FOUNDATION | Jackson | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $4.2M | 0 |
| COUNCIL OF COMMUNITY SERVICES | Gillette | S200 Community Improvement & Capacity Building | $4.1M | 0 |
| GOODWILL INDUSTRIES OF WY INC | Cheyenne | J32Z Employment | $4M | 1 |
| SENIOR CENTER OF JACKSON HOLE INC | Jackson | — | $4M | 2 |
| ANDERSON DONOR ADVISED CHARITABLE FUND | Cheyenne | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $4M | 0 |
| Community Center for the Arts | Jackson | A20 Arts, Culture & Humanities | $3.9M | 1 |
| THE MARTIN FAMILY FOUNDATION | Casper | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.8M | 0 |
| MENTAL HEALTH & RECOVERY SERVICES OF JACKSON HOLE | Jackson | — | $3.8M | 3 |
| CHEYENNE COUNTRY CLUB | Cheyenne | — | $3.7M | 0 |
| HABITAT FOR HUMANITY OF THE EASTERN | Sheridan | — | $3.7M | 0 |
| GRAND TETON ASSOCIATION | Moose | A56Z Arts, Culture & Humanities | $3.6M | 2 |
| SHERIDAN COMMUNITY LAND TRUST | Sheridan | C34 Environment | $3.6M | 1 |
| LUTHER CLASSICAL COLLEGE | Casper | B42 Education | $3.6M | 4 |
| THE NORTHSTAR FOUNDATION | Alpine | P99 Human Services | $3.5M | 0 |
| THE WYLDLIFE FUND | Buffalo | D30 Animal-Related | $3.5M | 1 |
| WYOMING EDUCATION ASSOCIATION | Cheyenne | — | $3.4M | 2 |
| CASPER COUNTRY CLUB | Casper | — | $3.4M | 1 |
| PIKE & SUSAN SULLIVAN CHARITABLE | Cheyenne | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.4M | 0 |
| LODGE NO 390 LARAMIE LOYAL ORDER OF MOOSE | Laramie | — | $3.4M | 0 |
| LYNN & FOSTER FRIESS FAMILY | Jackson | X20Z Religion-Related | $3.4M | 1 |
| WYOMING COALITION AGAINST DOMESTIC | Laramie | — | $3.3M | 0 |
| CHILD DEVELOPMENT CENTER - REGION II | Sheridan | E20Z Health Care | $3.3M | 0 |
| WESTERN RESEARCH INSTITUTE | Laramie | B43 Education | $3.3M | 4 |
| WESTERN FUTURES FUND INC | Sheridan | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $3.3M | 0 |
| CHALTEN TRUST | Jackson | C01 Environment | $3.2M | 1 |
| SOJOURNER TRUST | Jackson | — | $3.2M | 1 |
| CENTRAL WYOMING COLLEGE FOUNDATION | Riverton | — | $3.2M | 2 |
| Snowy Range Academy | Laramie | B29 Education | $3.2M | 2 |
| PODER ACADEMY | Cheyenne | B29 Education | $3.2M | 1 |
| CODY STAMPEDE INC | Cody | — | $3.1M | 1 |
| BOYS AND GIRLS CLUB OF CHEYENNE | Cheyenne | P20 Human Services | $3.1M | 3 |
| Jackson Hole Community School | Jackson | B25 Education | $3.1M | 3 |
| THE NEW MUSEUM AT THE BRADFORD BRINTON | Big Horn | A51 Arts, Culture & Humanities | $3.1M | 3 |
| THE WILDER TRUST | Jackson | C01 Environment | $3M | 1 |
| TAIL WIND TRUST | Jackson | C01 Environment | $2.9M | 1 |
| CHILD DEVELOPMENT SERVICES OF FREMONT | Lander | B22Z Education | $2.9M | 2 |
| Casper Family YMCA INC | Casper | — | $2.9M | 1 |
| COMMUNITY ACTION OF LARAMIE COUNTY | Cheyenne | P20Z Human Services | $2.8M | 2 |
| CHEYENNE ANIMAL SHELTER | Cheyenne | D200 Animal-Related | $2.8M | 1 |
| Homer A Scott & Mildred S Scott Foundation | Sheridan | — | $2.8M | 2 |
| Thurston Family Foundation | Jackson | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $2.8M | 0 |
| THE TVRC EDUCATION FOUNDATION INC | Jackson | O43 Youth Development | $2.8M | 1 |
| JACKSON HOLE SKI & SNOWBOARD CLUB | Jackson | N60Z Recreation & Sports | $2.8M | 1 |
| WYOMING OUTDOOR COUNCIL | Lander | C016 Environment | $2.7M | 1 |
| HOME VENTILATING INSTITUTE INC | Cheyenne | — | $2.7M | 7 |
| PODER ACADEMY SECONDARY SCHOOL | Cheyenne | B29 Education | $2.7M | 2 |
| MOUNTAIN REGIONAL SERVICES INC | Evanston | P730 Human Services | $2.7M | 1 |
| SUBLETTE CENTER | Pinedale | — | $2.7M | 2 |
