| LENSIC PERFORMING ARTS CENTER | Santa Fe | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $8.7M | 4 |
| NEW MEXICO VETERANS INTEGRATION | Albuquerque | P200 Human Services | $8.7M | 1 |
| ALL FAITHS | Albuquerque | P400 Human Services | $8.5M | 5 |
| EXPLORA SCIENCE CENTER & CHILDREN'S | Albuquerque | A520 Arts, Culture & Humanities | $8.5M | 2 |
| EUGENE V AND CLARE E THAW | Santa Fe | — | $8.4M | 1 |
| FIRST SERVE-NM INC | Santa Fe | N66 Recreation & Sports | $8.4M | 0 |
| ENCINO GARDENS INC | Albuquerque | L22Z Housing & Shelter | $8.4M | 0 |
| NACA-INSPIRED SCHOOLS NETWORK | Albuquerque | B19 Education | $8.4M | 1 |
| NEW MEXICO ASSOCIATION OF COUNTIES | Santa Fe | — | $8.3M | 8 |
| ANIMAL HUMANE ASSOCIATION OF | Albuquerque | D200 Animal-Related | $8.1M | 3 |
| MENTAL HEALTH RESOURCES INC | Clovis | F30Z Mental Health & Crisis Intervention | $8.1M | 1 |
| ZIA THERAPY CENTER INC | Alamogordo | P200 Human Services | $8M | 1 |
| LIFEROOTS INC | Albuquerque | — | $8M | 3 |
| TIERRA DEL SOL HOUSING CORPORATION | Las Cruces | — | $7.9M | 1 |
| INDIGENOUS EDUCATION INC | Albuquerque | B82 Education | $7.8M | 1 |
| Rehoboth Christian School Assoc | Rehoboth | B200 Education | $7.8M | 2 |
| LAS CLINICAS DEL NORTE INC | El Rito | E300 Health Care | $7.8M | 2 |
| LAS CUMBRES COMMUNITY SERVICES | Espanola | P820 Human Services | $7.7M | 4 |
| INDIAN PUEBLO CULTURAL CENTER | Albuquerque | A500 Arts, Culture & Humanities | $7.7M | 6 |
| NATIONAL GHOST RANCH FOUNDATION | Abiquiu | X20Z Religion-Related | $7.7M | 3 |
| NATIONAL INDIAN COUNCIL ON AGING | Albuquerque | — | $7.6M | 3 |
| FUTURE FOCUSED EDUCATION | Albuquerque | B02 Education | $7.6M | 3 |
| YES HOUSING INC | Albuquerque | Z99Z Unknown | $7.5M | 7 |
| Sheet Metal Workers Local 49 Family | Albuquerque | — | $7.4M | 0 |
| SANDIA FOUNDATION | Albuquerque | B120 Education | $7.4M | 16 |
| CENTRAL NEW MEXICO HOUSING CORP | Albuquerque | L81 Housing & Shelter | $7.3M | 2 |
| A BETTER WAY OF LIVING INC | Albuquerque | P82 Human Services | $7.3M | 0 |
| ALBUQUERQUE COUNTRY CLUB | Albuquerque | — | $7.2M | 3 |
| LA VIDA FELICIDAD INC | Los Lunas | — | $7.2M | 5 |
| NONVIOLENCE WORKS INC | Taos | P80 Human Services | $7.1M | 0 |
| ARTESIA CREDIT UNION | Artesia | — | $7M | 3 |
| THE NEIGHBORHOOD IN RIO RANCHO | Rio Rancho | L22 Housing & Shelter | $7M | 0 |
| SANTA FE ANIMAL SHELTER AND HUMANE | Santa Fe | D200 Animal-Related | $6.9M | 6 |
| ANIMAS FOUNDATION | Animas | — | $6.8M | 1 |
| MENAUL SCHOOL | Albuquerque | B24Z Education | $6.8M | 3 |
| Albuquerque Sign Language Academy | Albuquerque | B29 Education | $6.8M | 1 |
| MESILLA VALLEY HOSPICE INC | Las Cruces | P74Z Human Services | $6.7M | 5 |
| JEWISH COMMUNITY CENTER OF GREATER | Albuquerque | P99 Human Services | $6.7M | 6 |
| SAN JUAN CENTER FOR INDEPENDENCE | Farmington | P800 Human Services | $6.7M | 0 |
| J & J HOME CARE INC | Artesia | P70 Human Services | $6.7M | 5 |
| GROWING UP NEW MEXICO INC | Santa Fe | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $6.6M | 4 |
| BIOMEDICAL RESEARCH INSTITUTE | Albuquerque | H99E Medical Research | $6.6M | 6 |
| DZILTH-NA-O-DITH-HLE COMMUNITY | Bloomfield | B29 Education | $6.5M | 5 |
| SITE SANTA FE | Santa Fe | A51Z Arts, Culture & Humanities | $6.5M | 2 |
| THE O'KEEFFE MUSEUM FOUNDATION | Santa Fe | A11 Arts, Culture & Humanities | $6.5M | 0 |
| CATHOLIC CHARITIES | Albuquerque | P20Z Human Services | $6.5M | 2 |
| Cuidando Los Nios Inc | Albuquerque | P33Z Human Services | $6.3M | 2 |
| CARLSBAD LIFEHOUSE INC | Carlsbad | F20 Mental Health & Crisis Intervention | $6.3M | 1 |
| LA COSECHA COMMUNITY SUPPORTED | Albuquerque | P20 Human Services | $6.2M | 0 |
| Artesia Recreation Center Foundation | Artesia | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $6.2M | 0 |
