| LIFE SCIENCES GREENHOUSE OF | Harrisburg | S40 Community Improvement & Capacity Building | $2.5M | 3 |
| LIBERTAE INCORPORATED | Bensalem | F22Z Mental Health & Crisis Intervention | $2.5M | 1 |
| UNION FIRE COMPANY NO 1 | Oxford | E62Z Health Care | $2.5M | 0 |
| PHMC WEST (FORMERLY RESEARCH | Philadelphia | B20E Education | $2.5M | 1 |
| THE AMERICAN BOARD OF ALLERGY AND | Philadelphia | — | $2.5M | 14 |
| NAMI KEYSTONE PENNSYLVANIA | Pittsburgh | F992 Mental Health & Crisis Intervention | $2.5M | 2 |
| Hosanna Industries Inc | Gibsonia | L200 Housing & Shelter | $2.5M | 1 |
| UNION MISSION OF LATROBE INC | Latrobe | — | $2.5M | 1 |
| THE OEIS FOUNDATION INC | Monroeville | A30 Arts, Culture & Humanities | $2.5M | 1 |
| FRINGEARTS | Philadelphia | A200 Arts, Culture & Humanities | $2.5M | 2 |
| LEBANON COUNTY CHRISTIAN MINISTRIES | Lebanon | — | $2.5M | 0 |
| HABITAT FOR HUMANITY OF BERKS COUNTY | Reading | — | $2.5M | 1 |
| COTTAGE HOSE AMBULANCE CORPS INC | Carbondale | — | $2.5M | 1 |
| SAMARITAN CENTER | Lancaster | — | $2.5M | 1 |
| BUHL COMMUNITY RECREATION CENTER | Sharon | — | $2.5M | 1 |
| SEED THE DREAM FOUNDATION | Gladwyne | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $2.5M | 0 |
| Big Brothers Big Sisters of Greater | Pittsburgh | I21Z Crime & Legal-Related | $2.5M | 3 |
| Pennsylvania Humanities Council | Philadelphia | A700 Arts, Culture & Humanities | $2.5M | 4 |
| PITTSBURGH FEDERATION OF TEACHERS | Pittsburgh | — | $2.5M | 6 |
| MACUNGIE AMBULANCE CORPS | Macungie | M23 Public Safety, Disaster Preparedness & Relief | $2.5M | 0 |
| LABORERS INTERNATIONAL UNION OF NOR | Croydon | — | $2.5M | 13 |
| CENTRE SAFE | State College | P43Z Human Services | $2.5M | 2 |
| HIGHLAND LAKE MANOR CORP | Hughesville | N61 Recreation & Sports | $2.5M | 0 |
| NATIONAL ASSOCIATION OF WATCH AND CLOCK | Columbia | A50 Arts, Culture & Humanities | $2.5M | 3 |
| DOMESTIC VIOLENCE SERVICES OF | Brownsville | P430 Human Services | $2.5M | 2 |
| LAUREL HILL CEMETERY CO-LOT HOLDERS FDS | Bala Cynwyd | — | $2.5M | 6 |
| THE BENTER FOUNDATION | Pittsburgh | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $2.5M | 0 |
| Logan Hope | Philadelphia | B24 Education | $2.5M | 1 |
| Young Mens Christian Association of | Corry | — | $2.5M | 1 |
| WASHINGTON COUNTY TOURISM PROMOTION | Canonsburg | — | $2.5M | 1 |
| The Friendship Circle of Pittsburgh Inc | Pittsburgh | P30 Human Services | $2.5M | 2 |
| ENGLAND ELIZABETH R - UW | Pittsburgh | — | $2.5M | 1 |
| MON VALLEY YMCA INC | Monongahela | — | $2.5M | 1 |
| Erie Philharmonic Inc | Erie | A690 Arts, Culture & Humanities | $2.4M | 3 |
| THE LIBRARY COMPANY OF PHILADELPHIA | Philadelphia | B76Z Education | $2.4M | 2 |
| PENNSYLVANIA DENTAL ASSOCIATION | Harrisburg | — | $2.4M | 18 |
| Uncommon Individual Foundation | Bryn Mawr | — | $2.4M | 1 |
| CRISPUS ATTUCKS CHARTER SCHOOL | York | B29 Education | $2.4M | 1 |
| ROXBOROUGH HOME FOR WOMEN | Philadelphia | L22 Housing & Shelter | $2.4M | 0 |
| The Montessori School | Dresher | — | $2.4M | 1 |
| COLKET FAMILY FOUNDATION | Newtown Square | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $2.4M | 4 |
| KENCREST SVCS INC WORKERS COMP TRUST | Jenkintown | — | $2.4M | 0 |
| TOPTON COMMUNITY AMBULANCE | Mertztown | E62Z Health Care | $2.4M | 1 |
| THE FORMAN FAMILY FOUNDATION | Philadelphia | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $2.4M | 1 |
| COMMUNITY CENTER ASSOCIATION | Pittsburgh | P20 Human Services | $2.4M | 2 |
| SECURE REHABILITATION AND | Monroeton | J33Z Employment | $2.4M | 2 |
| AERIS INSIGHT INC | Philadelphia | S31 Community Improvement & Capacity Building | $2.4M | 5 |
| CHILDREN'S AID SOCIETY OF MERCER COUNTY | Mercer | — | $2.4M | 3 |
| FERREE FOUNDATION | Lancaster | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $2.4M | 1 |
| HEALTH ALLIANCE FOR NONPROFITS | Wexford | — | $2.4M | 1 |