| CHILDREN OF HEROES OF UKRAINE FOUNDATION | Denver | Q33 International, Foreign Affairs & National Security | $4.4M | 2 |
| DENVER EARLY CHILDHOOD COUNCIL | Denver | B19 Education | $4.4M | 2 |
| INTERNATIONAL ASSOCIATION OF MACHINISTS & AEROSPACE WORKERS | Denver | — | $4.4M | 12 |
| WESTERN CONSERVATION ACTION | Denver | R40 Civil Rights, Social Action & Advocacy | $4.4M | 5 |
| MUSANA COMMUNITY DEVELOPMENT | Centennial | P70 Human Services | $4.4M | 2 |
| BENEFITS IN ACTION | Lakewood | P50 Human Services | $4.4M | 1 |
| NATIONAL SPORTS CENTER FOR THE | Golden | N60Z Recreation & Sports | $4.4M | 2 |
| SOCIETY OF ECONOMIC GEOLOGISTS INC | Littleton | B03 Education | $4.3M | 4 |
| STALEY FAMILY FOUNDATION | Avon | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.3M | 0 |
| COLORADO BAR ASSOCIATION | Denver | — | $4.3M | 9 |
| DEL NORTE NEIGHBORHOOD DEVELOPMENT | Denver | L250 Housing & Shelter | $4.3M | 1 |
| National Foundation Inc | Colorado Springs | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $4.3M | 5 |
| COMMUNITY REACH CENTER FOUNDATION | Westminster | — | $4.3M | 3 |
| New Legacy Charter School | Aurora | B29 Education | $4.3M | 1 |
| GLOBAL DOWN SYNDROME FOUNDATION | Denver | E12 Health Care | $4.3M | 2 |
| DOCTORS CARE | Littleton | E30Z Health Care | $4.3M | 1 |
| METROPOLITAN DENVER HOMELESS | Denver | L80 Housing & Shelter | $4.3M | 1 |
| Entrust | Colorado Springs | X20Z Religion-Related | $4.3M | 2 |
| DSST PUBLIC SCHOOLS FOUNDATION | Denver | B11 Education | $4.3M | 0 |
| COLORADO OUTWARD BOUND SCHOOL | Leadville | C600 Environment | $4.3M | 1 |
| ARAPAHOE COUNTY EARLY CHILDHOOD COUNCIL | Centennial | B90 Education | $4.3M | 1 |
| The Flying Horse Foundation | Colorado Springs | P20 Human Services | $4.3M | 0 |
| ROOTED | Denver | B90 Education | $4.3M | 4 |
| AXIS International Academy | Fort Collins | B29 Education | $4.3M | 1 |
| United Way of Pueblo County | Pueblo | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $4.3M | 1 |
| Paragon Behavioral Health Connections | Lakewood | F30 Mental Health & Crisis Intervention | $4.3M | 9 |
| Homeward Pikes Peak | Colorado Springs | L41 Housing & Shelter | $4.2M | 2 |
| Colorado International Language Academy | Colorado Springs | B29 Education | $4.2M | 0 |
| RINO ART DISTRICT | Denver | S41 Community Improvement & Capacity Building | $4.2M | 1 |
| HOSPICE OF THE VALLEY INC | Glenwood Springs | P74 Human Services | $4.2M | 5 |
| THE GREELEY COUNTRY CLUB | Greeley | — | $4.2M | 1 |
| Community Hospital Foundation | Grand Junction | E22 Health Care | $4.2M | 3 |
| BOULDER COUNTY UNITED | Lafayette | N64Z Recreation & Sports | $4.2M | 0 |
| St Vrain Community Montessori School | Longmont | B29 Education | $4.2M | 1 |
| KNOPH FAMILY FOUNDATION | Greeley | A20 Arts, Culture & Humanities | $4.2M | 0 |
| ST ELIZABETH'S SCHOOL | Denver | B20 Education | $4.2M | 1 |
| TEAM SUMMIT | Copper Mountain | N60 Recreation & Sports | $4.2M | 1 |
| Garden of the Gods Foundation | Colorado Springs | C11 Environment | $4.2M | 1 |
| NATIVE AMERICAN FISH & WILDLIFE SOCIETY | Northglenn | D033 Animal-Related | $4.2M | 1 |
| ONWARD A LEGACY FOUNDATION | Cortez | B82 Education | $4.2M | 1 |
| PEMA FOUNDATION INC | Denver | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.2M | 0 |
| ACADEMY 360 | Denver | B29 Education | $4.1M | 1 |
| SOUTHERN COLORADO DEVELOPMENTAL | Trinidad | — | $4.1M | 0 |
| ASSISI HOMES-BATAVIA APARTMENTS INC | Denver | L210 Housing & Shelter | $4.1M | 7 |
| SENIORS' RESOURCE CENTER INC | Denver | P81Z Human Services | $4.1M | 1 |
| PROJECT WORTHMORE | Aurora | P20 Human Services | $4.1M | 3 |
| MT CARMEL VETERANS SERVICE CENTER | Colorado Springs | J20 Employment | $4.1M | 0 |
| COLORADO WHEAT RESEARCH FOUNDATION | Fort Collins | — | $4.1M | 2 |
| Wish of a Lifetime | Denver | P60 Human Services | $4.1M | 9 |
| CHAMPION MINISTRIES INC | Castle Rock | O55 Youth Development | $4.1M | 1 |
