| EARLY CHILDHOOD COUNCIL OF THE SAN LUIS VALLEY INC | Alamosa | P02 Human Services | $4.6M | 3 |
| CASTLE ROCK COMMUNITY INTER CHURCH TASK FORCE | Castle Rock | P60Z Human Services | $4.6M | 1 |
| COLORADO WHEAT RESEARCH FOUNDATION | Fort Collins | — | $4.6M | 1 |
| Highlands Classical Academy dba Augustine Classical Academy | Lakewood | B20 Education | $4.6M | 1 |
| Peoples Credit Union | Springfield | — | $4.6M | 1 |
| Compass Academy | Denver | B25 Education | $4.6M | 2 |
| Colorado Succeeds | Denver | B05 Education | $4.6M | 5 |
| BUILD CHANGE | Denver | U40 Science & Technology | $4.6M | 8 |
| ALPHA PHI INTERNATIONAL FRATERNITY- BETA MU CHAPTER | Denver | — | $4.6M | 0 |
| DRALA MOUNTAIN CENTER Formerly Shambhala Mountain Center | Red Feather Lakes | X50 Religion-Related | $4.6M | 2 |
| RICARDO FLORES MAGON ACADEMYINCORPORATED | Denver | — | $4.6M | 1 |
| VINDEKET | Fort Collins | K30 Food, Agriculture & Nutrition | $4.5M | 1 |
| GREENHOUSE SCHOLARS | Boulder | B82 Education | $4.5M | 4 |
| PARACLETE MISSION GROUP INC | Colorado Springs | X02 Religion-Related | $4.5M | 1 |
| THE ARVADA COMMUNITY FOOD BANK dba COMMUNITY TABLE | Arvada | K31Z Food, Agriculture & Nutrition | $4.5M | 1 |
| TELLURIDE COUNCIL FOR THE ARTS AND HUMANITIES | Telluride | — | $4.5M | 1 |
| ROCKY MOUNTAIN BIOLOGICAL LABORATORY AT GOTHIC | Crested Butte | U50Z Science & Technology | $4.5M | 5 |
| JEROME V BRUNI FOUNDATION | Colorado Springs | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.5M | 0 |
| COMPETENCY & CREDENTIALING INSTITUTE | Littleton | — | $4.5M | 5 |
| GLOBAL SERVICE OFFICE | Lafayette | — | $4.5M | 2 |
| Sachs Foundation | Colorado Springs | B82 Education | $4.5M | 5 |
| COLORADO RURAL HEALTH CENTER | Centennial | E20Z Health Care | $4.5M | 5 |
| MOUNTAIN STATES LEGAL FOUNDATION | Lakewood | R600 Civil Rights, Social Action & Advocacy | $4.5M | 7 |
| Bibles For The World | Colorado Springs | X21Z Religion-Related | $4.5M | 2 |
| THE LEARNING SOURCE | Denver | B61Z Education | $4.5M | 2 |
| Wyatt Academy | Denver | B20 Education | $4.5M | 1 |
| FRIENDS OF THE LONGMONT MUSEUM | Longmont | A50Z Arts, Culture & Humanities | $4.5M | 0 |
| DENVER RESEARCH INSTITUTE | Denver | E20Z Health Care | $4.5M | 4 |
| VISION HOME AND COMMUNITY | Delta | B29 Education | $4.4M | 2 |
| Rapha Foundation | Colorado Springs | X20 Religion-Related | $4.4M | 2 |
| COMMUNITY HOUSING DEVELOPMENT ASSOCIATION INC | Greenwood Village | L21 Housing & Shelter | $4.4M | 1 |
| DENVER URBAN GARDENS | Denver | C500 Environment | $4.4M | 1 |
| FAMILY GUIDANCE INSTITUTE | Alamosa | P190 Human Services | $4.4M | 5 |
| MAJOR LEAGUE BASEBALL PLAYERS ALUMNI ASSOCIATION | Colorado Springs | — | $4.4M | 8 |
| SOUTHERN COLORADO DEVELOPMENTAL DISABILITIES INC | Trinidad | — | $4.4M | 1 |
| VALLEY SETTLEMENT | Glenwood Springs | B90 Education | $4.4M | 4 |
| JUDI'S HOUSE INC | Aurora | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $4.4M | 4 |
| ROCKY MOUNTAIN CHILDREN'S HEALTH FOUNDATION | Arvada | P60 Human Services | $4.4M | 2 |
| Moonshot edVentures | Denver | B90 Education | $4.4M | 3 |
| PADDINGTON STATION INC | Denver | B21 Education | $4.4M | 2 |
| DENVER EARLY CHILDHOOD COUNCIL | Denver | B19 Education | $4.4M | 2 |
| WESTERN CONSERVATION ACTION | Denver | R40 Civil Rights, Social Action & Advocacy | $4.4M | 5 |
| MUSANA COMMUNITY DEVELOPMENT ORGANIZATION | Centennial | P70 Human Services | $4.4M | 2 |
| BENEFITS IN ACTION | Lakewood | P50 Human Services | $4.4M | 1 |
| NATIONAL SPORTS CENTER FOR THE DISABLED INC | Golden | N60Z Recreation & Sports | $4.4M | 2 |
| SOCIETY OF ECONOMIC GEOLOGISTS INC | Littleton | B03 Education | $4.3M | 4 |
| Joy To The World Foundation | Colorado Springs | P12 Human Services | $4.3M | 3 |
| COMMUNITY FOUNDATION SERVING SOUTHWEST COLORADO | Durango | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $4.3M | 1 |
| COLORADO BAR ASSOCIATION | Denver | — | $4.3M | 9 |
| DEL NORTE NEIGHBORHOOD DEVELOPMENT CORPORATION | Denver | L250 Housing & Shelter | $4.3M | 1 |
