| HOUSE OF MERCY | Des Moines | F220 Mental Health & Crisis Intervention | $5.1M | 7 |
| CAPSTONE BEHAVIORAL HEALTHCARE INC | Newton | — | $5.1M | 0 |
| HUBBARD CARE CENTER INC | Hubbard | P75Z Human Services | $5M | 1 |
| THE FAMILY LEADER FOUNDATION INC | Urbandale | B99 Education | $5M | 2 |
| PELLA CHRISTIAN HIGH SCHOOL SOCIETY | Pella | B20 Education | $5M | 0 |
| UNITY CHRISTIAN HIGH SCHOOL | Orange City | B25Z Education | $5M | 0 |
| MEMORIAL FOUNDATION OF ALLEN HOSPITAL | Waterloo | E112 Health Care | $4.9M | 8 |
| UNITED WAY AND COMMUNITY FOUNDATION | Fort Dodge | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $4.9M | 1 |
| IOWA HEALTH CARE ASSOCIATION | West Des Moines | — | $4.9M | 7 |
| IOWA WESTERN COMMUNITY COLLEGE | Council Bluffs | B90 Education | $4.9M | 3 |
| CROSSROADS INC | Muscatine | J300 Employment | $4.9M | 1 |
| LYON & SIOUX RURAL WATER SYSTEM INC | Rock Rapids | — | $4.9M | 0 |
| EMPLOYER CONTRIBUTION VEBA TRUST DENISON | Clinton | Y44 Mutual & Membership Benefit | $4.9M | 1 |
| LUTHERAN RETIREMENT HOME | Northwood | — | $4.9M | 1 |
| INTERNATIONAL BROTHERHOOD OF | Ankeny | — | $4.9M | 12 |
| Catholic Charities of the Archdiocese of | Dubuque | — | $4.9M | 2 |
| THE JARED AND CAROL HILLS FOUNDATION | Cedar Rapids | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $4.8M | 0 |
| NORTH STAR COMMUNITY SERVICES INC | Waterloo | J30Z Employment | $4.8M | 1 |
| FIGGE ART MUSEUM | Davenport | A20Z Arts, Culture & Humanities | $4.8M | 3 |
| INDIAN HILLS COMMUNITY COLLEGE | Ottumwa | B41I Education | $4.8M | 0 |
| SOUTH CENTRAL IOWA COMMUNITY | Chariton | S20Z Community Improvement & Capacity Building | $4.8M | 1 |
| CEDAR VALLEY FRIENDS OF THE FAMILY INC | Waterloo | — | $4.8M | 2 |
| CLARKE COUNTY DEVELOPMENT CORPORATION | Osceola | — | $4.8M | 0 |
| CLAY COUNTY FAIR ASSOCIATION INC | Spencer | — | $4.8M | 1 |
| MATURA ACTION CORPORATION | Creston | S200 Community Improvement & Capacity Building | $4.8M | 2 |
| Believers Stewardship Services Inc | Dubuque | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $4.8M | 1 |
| FIRST CLASS COMMUNITY CREDIT UNION | West Des Moines | — | $4.8M | 1 |
| PELLA ROLSCREEN FOUNDATION | Pella | — | $4.8M | 0 |
| THE LIFESPACE FOUNDATION | West Des Moines | — | $4.8M | 3 |
| YOUTH AND SHELTER SERVICES FOUNDATION I | Ames | — | $4.7M | 2 |
| IOWA ASSOCIATION OF SCHOOL BOARDS | Des Moines | — | $4.7M | 6 |
| VESTERHEIM NORWEGIAN-AMERICAN MUSEUM | Decorah | A500 Arts, Culture & Humanities | $4.7M | 2 |
| PRAIRIE VIEW LEASING | Sanborn | L220 Housing & Shelter | $4.7M | 3 |
| GREATER DES MOINES BOTANICAL GARDEN | Des Moines | C114 Environment | $4.7M | 2 |
| COMMUNITY UNITED CHILD CARE CENTERS INC | Cedar Falls | P33Z Human Services | $4.6M | 2 |
| IOWA GIRLS HIGH SCHOOL ATHLETIC UNION | West Des Moines | N70Z Recreation & Sports | $4.6M | 4 |
| New Visions Homeless Services | Council Bluffs | P20 Human Services | $4.5M | 3 |
| HORIZONS A FAMILY SERVICE ALLIANCE | Cedar Rapids | P73 Human Services | $4.5M | 2 |
| ROTARY CLUB OF EAGLE GROVE HOME INC | Eagle Grove | S82Z Community Improvement & Capacity Building | $4.5M | 0 |
| DES MOINES COUNCIL OF ST VINCENT DE | Windsor Heights | P20 Human Services | $4.5M | 1 |
| JULIE GREEN MINISTRIES | Davenport | X80 Religion-Related | $4.5M | 4 |
| IOWA YOUTH ATHLETIC FOUNDATION | Ames | N620 Recreation & Sports | $4.5M | 3 |
| International Union UAW Local 838 | Waterloo | — | $4.5M | 19 |
| BOYS AND GIRLS CLUBS OF THE | Waterloo | O21Z Youth Development | $4.4M | 1 |
| FELLOWSHIP VILLAGE | Inwood | P750 Human Services | $4.4M | 0 |
| IOWA HEARTLAND HABITAT FOR HUMANITY | Waterloo | L20Z Housing & Shelter | $4.4M | 1 |
| DES MOINES IRON WORKERS | Des Moines | — | $4.4M | 2 |
| GRAND HAVEN HOMES INC | Marion | — | $4.4M | 1 |
| HERITAGE AREA AGENCY ON AGING | Cedar Rapids | P20 Human Services | $4.4M | 4 |
| PAINTERS & ALLIED TRADES DISTRICT | Cedar Rapids | Y43 Mutual & Membership Benefit | $4.4M | 0 |
