| PEO Educational Loan Fund | Des Moines | B82 Education | $5.3M | 0 |
| GRINNELL COLLEGE MEDICAL BENEFIT PLAN TRUST | Grinnell | — | $5.3M | 3 |
| LAKESIDE LUTHERAN HOME | Emmetsburg | P750 Human Services | $5.3M | 0 |
| IOWA HEALTH CARE ASSOCIATION FOUNDATION | West Des Moines | — | $5.3M | 1 |
| CENTRAL IOWA HEALTH PROPERTIES CORPORATION | Des Moines | — | $5.3M | 4 |
| MILESTONES AREA AGENCY ON AGING | Davenport | P81Z Human Services | $5.3M | 2 |
| GREAT RIVER FOUNDATION INC | West Burlington | — | $5.2M | 3 |
| John Ruan Foundation Trust | Urbandale | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 0 |
| FRIENDSHIP HOME ASSOCIATION | Audubon | E91Z Health Care | $5.2M | 2 |
| GREAT OUTDOORS FOUNDATION | West Des Moines | D110 Animal-Related | $5.2M | 1 |
| C S A | West Des Moines | P20 Human Services | $5.2M | 1 |
| Ruthven Community Care Center Inc | Ruthven | E910 Health Care | $5.1M | 0 |
| LYON & SIOUX RURAL WATER SYSTEM INC | Rock Rapids | — | $5.1M | 0 |
| RIVERMONT COLLEGIATE | Bettendorf | B200 Education | $5.1M | 2 |
| AMERICAN FREE ENTERPRISE CHAMBER OF COMMERCE | Ankeny | S41 Community Improvement & Capacity Building | $5.1M | 3 |
| ROTARY CLUB OF EAGLE GROVE HOME INC | Eagle Grove | S82Z Community Improvement & Capacity Building | $5.1M | 0 |
| SIOUXLAND COMMUNITY CHRISTIAN SCHOOL | Sioux City | B20 Education | $5.1M | 2 |
| WASHINGTON COUNTY RIVERBOAT FOUNDATION INC | Washington | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $5.1M | 1 |
| ZION INTEGRATED BEHAVIORAL HEALTH SERVICES | Atlantic | F22Z Mental Health & Crisis Intervention | $5.1M | 2 |
| RIVER VALLEY CREDIT UNION | Ames | — | $5.1M | 3 |
| CAPSTONE BEHAVIORAL HEALTHCARE INC | Newton | — | $5.1M | 1 |
| HUBBARD CARE CENTER INC | Hubbard | P75Z Human Services | $5M | 1 |
| THE FAMILY LEADER FOUNDATION INC | Urbandale | B99 Education | $5M | 2 |
| LUTHERAN RETIREMENT HOME | Northwood | — | $5M | 2 |
| PELLA CHRISTIAN HIGH SCHOOL SOCIETY | Pella | B20 Education | $5M | 0 |
| UNITY CHRISTIAN HIGH SCHOOL | Orange City | B25Z Education | $5M | 0 |
| Raam Raj Foundation | Fairfield | Q21 International, Foreign Affairs & National Security | $5M | 3 |
| IOWA HEALTH CARE ASSOCIATION | West Des Moines | — | $4.9M | 7 |
| IOWA WESTERN COMMUNITY COLLEGE FOUNDATION | Council Bluffs | B90 Education | $4.9M | 3 |
| CROSSROADS INC | Muscatine | J300 Employment | $4.9M | 1 |
| DEWOLF FAMILY FOUNDATION | Cedar Rapids | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.9M | 0 |
| EMPLOYER CONTRIBUTION VEBA TRUST DENISON UNIVERSITY | Clinton | Y44 Mutual & Membership Benefit | $4.9M | 1 |
| Catholic Charities of the Archdiocese of Dubuque | Dubuque | — | $4.9M | 2 |
| FIGGE ART MUSEUM | Davenport | A20Z Arts, Culture & Humanities | $4.8M | 3 |
| SOUTH CENTRAL IOWA COMMUNITY ACTION PROGRAM INC | Chariton | S20Z Community Improvement & Capacity Building | $4.8M | 1 |
| CLARKE COUNTY DEVELOPMENT CORPORATION | Osceola | — | $4.8M | 0 |
| FIRST CLASS COMMUNITY CREDIT UNION | West Des Moines | — | $4.8M | 3 |
| MATURA ACTION CORPORATION | Creston | S200 Community Improvement & Capacity Building | $4.8M | 2 |
| Believers Stewardship Services Inc | Dubuque | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $4.8M | 1 |
| PELLA ROLSCREEN FOUNDATION C/O PELLA CORPORATION | Pella | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.8M | 0 |
| THE LIFESPACE FOUNDATION | West Des Moines | — | $4.8M | 3 |
| IOWA PIPE TRADES & HVAC TRAINING INSTITUTE | Des Moines | — | $4.8M | 6 |
| BERGMAN ACADEMY | Des Moines | — | $4.7M | 2 |
| IOWA ASSOCIATION OF SCHOOL BOARDS | Des Moines | — | $4.7M | 6 |
| TELLIGEN COMMUNITY INITIATIVE | West Des Moines | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $4.7M | 1 |
| VESTERHEIM NORWEGIAN-AMERICAN MUSEUM | Decorah | A500 Arts, Culture & Humanities | $4.7M | 2 |
| PRAIRIE VIEW LEASING | Sanborn | L220 Housing & Shelter | $4.7M | 3 |
| LISA AND MIKE MCGRATH FAMILY FOUNDATION | Cedar Rapids | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $4.6M | 0 |
| COMMUNITY UNITED CHILD CARE CENTERS INC | Cedar Falls | P33Z Human Services | $4.6M | 2 |
| CARING HEARTS OF WEST CENTRAL IOWA | Carroll | P20 Human Services | $4.6M | 1 |
