| BLACK HAWK COUNTY GAMING ASSOCIATION | Waterloo | S31 Community Improvement & Capacity Building | $5.7M | 1 |
| ANKENY CHRISTIAN ACADEMY | Ankeny | — | $5.7M | 1 |
| UNITED ASSOCIATION OF JOURNEYMEN & | Des Moines | — | $5.7M | 10 |
| MONSOON ASIANS & PACIFIC ISLANDERS IN | Des Moines | P84 Human Services | $5.7M | 1 |
| HUMILITY HOMES AND SERVICES INC | Davenport | L40 Housing & Shelter | $5.7M | 3 |
| TRANSAMERICA INSTITUTE | Cedar Rapids | B60 Education | $5.7M | 0 |
| GDMCF CHARITABLE TRUST | Des Moines | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $5.7M | 1 |
| FRIENDSHIP ARK INC | Ames | L20 Housing & Shelter | $5.7M | 1 |
| HOOVER PRESIDENTIAL FOUNDATION | West Branch | — | $5.7M | 0 |
| QUAD CITIES CHAMBER OF COMMERCE | Davenport | S41 Community Improvement & Capacity Building | $5.6M | 6 |
| IOWA ASSOCIATION OF MUNICIPAL | Ankeny | — | $5.6M | 6 |
| THE CRITTENTON CENTER | Sioux City | P300 Human Services | $5.6M | 1 |
| CEDAR FOUNDATION INC | Tipton | P750 Human Services | $5.6M | 0 |
| NORTH CENTRAL SOYBEAN RESEARCH PROGRAM | Ankeny | U00Z Science & Technology | $5.6M | 0 |
| IOWA 80 TRUCKING MUSEUM | Walcott | A54 Arts, Culture & Humanities | $5.6M | 0 |
| CENTRAL IOWA SHELTER & SERVICES | Des Moines | L99Z Housing & Shelter | $5.6M | 2 |
| SOUTHERN IOWA MENTAL HEALTH CENTER | Ottumwa | F32Z Mental Health & Crisis Intervention | $5.6M | 0 |
| North Central Sheltered Workshop | Fort Dodge | J330 Employment | $5.6M | 0 |
| FRIENDS OF ROCK VALLEY | Rock Valley | S21 Community Improvement & Capacity Building | $5.6M | 0 |
| IOWA CITY HOSPICE INC | Iowa City | P74Z Human Services | $5.6M | 3 |
| OTTO SCHOITZ FOUNDATION | Waterloo | E19 Health Care | $5.6M | 1 |
| EMPLOYER CONTRIBUTION VEBA TRUST KENYON | Clinton | Y43 Mutual & Membership Benefit | $5.6M | 1 |
| SERVE CREDIT UNION | Des Moines | — | $5.6M | 0 |
| Camp Foster YMCA of the Okoboji's | Spirit Lake | P27Z Human Services | $5.6M | 1 |
| Iowa Medical Education Collaborative | Des Moines | B50 Education | $5.6M | 0 |
| Evans Memorial Home for the Aged Inc | Cresco | — | $5.6M | 1 |
| INNOVATIVE INDUSTRIES INC | Creston | — | $5.5M | 0 |
| CHILDSERVE CLINIC INC | Johnston | E32 Health Care | $5.5M | 5 |
| DMACC FOUNDATION | Ankeny | B12 Education | $5.5M | 2 |
| HOSPICE OF NORTH IOWA | Mason City | P74Z Human Services | $5.4M | 11 |
| CENTER FOR ALCOHOL & DRUG SERVICES INC | Davenport | F220 Mental Health & Crisis Intervention | $5.4M | 9 |
| THE COMMUNITY THEATRE OF CEDAR RAPIDS | Cedar Rapids | A65Z Arts, Culture & Humanities | $5.4M | 1 |
| MISSISSIPPI VALLEY FAIR INC | Davenport | — | $5.4M | 1 |
| AMERICAN HOME FINDING ASSOCIATION | Ottumwa | P310 Human Services | $5.3M | 0 |
| C S A | West Des Moines | P20 Human Services | $5.3M | 1 |
| WESTERN CHRISTIAN HIGH SCHOOL | Sioux Center | — | $5.3M | 0 |
| DUBUQUE GOLF & COUNTRY CLUB | Dubuque | — | $5.3M | 1 |
| JOURNEY CREDIT UNION | Des Moines | — | $5.3M | 2 |
| GRINNELL COLLEGE MEDICAL BENEFIT PLAN | Grinnell | — | $5.3M | 3 |
| IOWA HEALTH CARE ASSOCIATION FOUNDATION | West Des Moines | — | $5.3M | 1 |
| CENTRAL IOWA HEALTH PROPERTIES | Des Moines | — | $5.3M | 4 |
| GREAT RIVER FOUNDATION INC | West Burlington | — | $5.2M | 3 |
| John Ruan Foundation Trust | Urbandale | — | $5.2M | 0 |
| FRIENDSHIP HOME ASSOCIATION | Audubon | E91Z Health Care | $5.2M | 2 |
| PANHANDLE NON-UNION VEBA RETIREE HEALTH CARE | Des Moines | Y43 Mutual & Membership Benefit | $5.1M | 1 |
| Ruthven Community Care Center Inc | Ruthven | E910 Health Care | $5.1M | 0 |
| RIVERMONT COLLEGIATE | Bettendorf | B200 Education | $5.1M | 2 |
| MEMBERS COMMUNITY CREDIT UNION | Muscatine | — | $5.1M | 2 |
| WASHINGTON COUNTY RIVERBOAT | Washington | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $5.1M | 1 |
| ZION INTEGRATED BEHAVIORAL HEALTH | Atlantic | F22Z Mental Health & Crisis Intervention | $5.1M | 2 |
