| Arkansas Pharmacists Association | Little Rock | — | $6.3M | 4 |
| ADVANCED CARE HOSPITAL OF WHITE COUNTY | Searcy | E240 Health Care | $6.2M | 7 |
| SOUTHWEST ARKANSAS COUNSELING & MENTAL | Texarkana | F32Z Mental Health & Crisis Intervention | $6.2M | 3 |
| Lifewater Inc | Bentonville | C32Z Environment | $6.1M | 3 |
| SOUTH ARKANSAS DEVELOPMENT CENTER | El Dorado | — | $6M | 2 |
| WHITAKER FAMILY FOUNDATION | Fayetteville | — | $6M | 1 |
| ST FRANCIS HOUSE INC | Little Rock | — | $5.9M | 1 |
| OZARK OPPORTUNITIES INC | Harrison | S200 Community Improvement & Capacity Building | $5.9M | 2 |
| Hospice of The Ozarks | Mountain Home | P74Z Human Services | $5.9M | 0 |
| Washington Regional Medical Foundation | Fayetteville | P20 Human Services | $5.8M | 6 |
| Harvest Texarkana Regional Food Bank Inc | Texarkana | K30 Food, Agriculture & Nutrition | $5.8M | 1 |
| JOHN 316 MINISTRIES INC | Charlotte | F22 Mental Health & Crisis Intervention | $5.8M | 0 |
| LEE COUNTY COOPERATIVE CLINIC | Marianna | E320 Health Care | $5.7M | 5 |
| SOUTH ARKANSAS REGIONAL HEALTH | El Dorado | F32Z Mental Health & Crisis Intervention | $5.7M | 3 |
| ARKANSAS LIVESTOCK SHOW ASSOCIATION | Little Rock | N520 Recreation & Sports | $5.7M | 1 |
| Canopy NWA | Fayetteville | S02 Community Improvement & Capacity Building | $5.7M | 0 |
| EXCELLERATE FOUNDATION CHARITABLE | Rogers | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $5.6M | 8 |
| OUACHITA ENRICHMENT CENTERS INC | Camden | J300 Employment | $5.6M | 1 |
| MERCY HEALTH FOUNDATION NORTHWEST | Rogers | — | $5.6M | 3 |
| CHILDRENS HOME INC | Paragould | P70 Human Services | $5.5M | 1 |
| SCHOLARMADE ACHIVEMENT PLACE OF ARKANSAS | Little Rock | B29 Education | $5.5M | 0 |
| CONSOLIDATED YOUTH SERVICES INC | Jonesboro | P36Z Human Services | $5.5M | 1 |
| Baptist Health Foundation Inc | Little Rock | E110 Health Care | $5.4M | 4 |
| COMMUNITY SCHOOL OF CLEBURNE COUNTY | Heber Springs | B28Z Education | $5.3M | 0 |
| TEEN CHALLENGE RANCH OF NW ARKANSAS | Morrow | F33 Mental Health & Crisis Intervention | $5.3M | 0 |
| BOYS & GIRLS CLUB OF BENTON CO INC | Bentonville | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 2 |
| COLUMBIA CHRISTIAN SCHOOL INC | Magnolia | B20 Education | $5.2M | 0 |
| Destined to WinFamily Outreach Ministries Inc | Bryant | X21Z Religion-Related | $5.2M | 1 |
| MOUNT OLIVE WATER ASSOCIATION | Elkins | — | $5.2M | 0 |
| THE DELTA SCHOOL | Wilson | B20 Education | $5.2M | 1 |
| BENTONVILLE CHILD CARE AND DEVELOPMENT | Bentonville | B22Z Education | $5.1M | 1 |
| PRESBYTERIAN URBAN COUNCIL | Little Rock | K30 Food, Agriculture & Nutrition | $5.1M | 2 |
| ARKANSAS HOSPITAL ASSOCIATION INC | Little Rock | — | $5.1M | 7 |
| OUR HEALTHY COMMUNITIES INC | Rogers | — | $5.1M | 0 |
| ABILITIES UNLIMITED OF HOT SPRINGS | Hot Springs | J30Z Employment | $5.1M | 0 |
| ARKANSAS HUNGER RELIEF ALLIANCE INC | Little Rock | K30 Food, Agriculture & Nutrition | $5M | 1 |
| SPECIAL OLYMPICS ARKANSAS INC | Little Rock | — | $5M | 1 |
| The Peel Compton Foundation | Bentonville | — | $5M | 1 |
| RENEWAL RANCH | Conway | P20 Human Services | $5M | 0 |
| Providence Christian Ministries Inc | Lowell | B20 Education | $5M | 0 |
| NORTHWEST ARKANSAS CHILDREN'S | Bentonville | P70Z Human Services | $5M | 1 |
| ARKANSAS EDUCATIONAL TELECOMMUNICATIONS NETWORK FO | Conway | A32Z Arts, Culture & Humanities | $4.9M | 0 |
| DELTA COUNSELING ASSOCIATES | Monticello | F30Z Mental Health & Crisis Intervention | $4.9M | 0 |
| THE JONES CENTER FOR FAMILIES INC | Springdale | P40 Human Services | $4.9M | 4 |
| SEVIER COUNTY DEVELOPMENTAL CENTER INC | Dequeen | P820 Human Services | $4.9M | 1 |
| HARDSCRABBLE COUNTRY CLUB | Fort Smith | — | $4.9M | 2 |
| LEGAL AID OF ARKANSAS | Springdale | I80Z Crime & Legal-Related | $4.8M | 1 |
| Hutchcraft Ministries Inc | Harrison | X21Z Religion-Related | $4.8M | 4 |
| GIRL SCOUTS - DIAMONDS OF ARKANSAS | Little Rock | Z99 Unknown | $4.8M | 3 |
| CROWLEYS RIDGE COLLEGE | Paragould | B41Z Education | $4.7M | 1 |
