| Herzog Tomorrow Foundation | Smithville | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $7.2M | 1 |
| ST VINCENT'S FOUNDATION INC | St Louis | — | $7.2M | 7 |
| BRANSONLAKES AREA CHAMBER OF COMMERCE | Branson | — | $7.2M | 6 |
| CONCERNS OF POLICE SURVIVORS INC | Camdenton | I60I Crime & Legal-Related | $7.2M | 1 |
| ANHEUSER-BUSCH FOUNDATION | Clayton | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.2M | 1 |
| GREATER KANSAS CITY LABORERS' VACATION PLAN | Kansas City | — | $7.2M | 0 |
| METROPOLITAN COMMUNITY COLLEGE FOUNDATION | Kansas City | B41I Education | $7.2M | 1 |
| TAYLOR FAMILY FOUNDATION | St Louis | P58 Human Services | $7.1M | 0 |
| CITY ACADEMY INC | St Louis | B24P Education | $7.1M | 4 |
| BETHESDA HEALTH GROUP INC | St Louis | P750 Human Services | $7.1M | 16 |
| ST LUKES MANAGEMENT CO INC | Carthage | — | $7.1M | 0 |
| TOLBERT EDUCATIONAL SERVICES INC | Kansas City | B12 Education | $7.1M | 0 |
| HABITAT FOR HUMANITY - ST LOUIS | St Louis | L20Z Housing & Shelter | $7.1M | 1 |
| BARNABAS FOUNDATION INC | Branson | X20 Religion-Related | $7.1M | 3 |
| Coyote Hill Foster Care Ministries | Harrisburg | P70Z Human Services | $7.1M | 3 |
| EPCOR | Kansas City | — | $7.1M | 6 |
| FIGHT COLORECTAL CANCER INC | Springfield | G30 Diseases, Disorders & Medical Disciplines | $7.1M | 1 |
| DEVELOPMENTAL CENTER OF THE OZARKS | Springfield | P820 Human Services | $7M | 1 |
| Ozarks Methodist Manor | Marionville | — | $7M | 2 |
| House of David Preservation Inc | Kansas City | L20 Housing & Shelter | $7M | 1 |
| UNITED COMMUNITY BUILDERS COMMUNITY DEVELOPMENT CO | Columbia | P20 Human Services | $7M | 1 |
| COLE COUNTY RESIDENTIAL SERVICES INC | Jefferson City | F34Z Mental Health & Crisis Intervention | $6.9M | 0 |
| ST LOUIS CRISIS NURSERY | St Louis | — | $6.9M | 3 |
| COMMERCE BANCSHARES FOUNDATION | Kansas City | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $6.9M | 0 |
| TRUMAN STATE UNIVERSITY FOUNDATION | Kirksville | B114 Education | $6.9M | 5 |
| Missouri Credit Union | Columbia | — | $6.9M | 9 |
| Missouri State Teachers Association Inc | Columbia | — | $6.9M | 6 |
| METRO CREDIT UNION | Springfield | — | $6.9M | 3 |
| BIOGENERATOR | St Louis | U50 Science & Technology | $6.9M | 7 |
| THE ROBERT R MACDONALD JR FOUNDATION | Weldon Spring | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $6.8M | 4 |
| INTERNATIONAL ASSOCIATION OF ASSESSING OFFICERS | Kansas City | — | $6.8M | 5 |
| URBAN SPROUTS | University City | P33 Human Services | $6.8M | 1 |
| CAPITAL CITY AREA COUNCIL FOR SPECIAL SERVICES | Jefferson City | B28Z Education | $6.8M | 2 |
| BOYS AND GIRLS CLUBS OF WEST CENTRAL MISSOURI | Sedalia | O23Z Youth Development | $6.8M | 0 |
| TW MARIAN W OTTLEY ATLANTA MAIN | Saint Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $6.8M | 1 |
| NEGRO LEAGUES BASEBALL MUSEUM INC | Kansas City | A500 Arts, Culture & Humanities | $6.8M | 0 |
| Stray Rescue of St Louis | Saint Louis | D200 Animal-Related | $6.8M | 2 |
| OAKHILL DAY SCHOOL | Gladstone | — | $6.8M | 1 |
| AMERICAN HEREFORD ASSOCIATION | Kansas City | — | $6.8M | 4 |
| St Mary's South Side Catholic High School | St Louis | B25 Education | $6.8M | 1 |
| KANSAS CITY REPERTORY THEATRE INC | Kansas City | A650 Arts, Culture & Humanities | $6.8M | 2 |
| Providence Health Services Inc | St Louis | E22B Health Care | $6.7M | 5 |
| COMMUNITY NETWORK FOR BEHAVIORAL HEALTHCARE INC | Kansas City | F300 Mental Health & Crisis Intervention | $6.7M | 1 |
| MACCARTHY FOUNDATION | St Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $6.7M | 0 |
| INTL BROTHERHOOD ELECTRICAL WORKERS IBEW LOCAL 53 | Kansas City | — | $6.7M | 20 |
| MID-STATES ORGANIZED CRIME INFORMATION CENTER | Springfield | I60L Crime & Legal-Related | $6.7M | 4 |
| KANSAS CITY GIRLS PREPARATORY ACADEMY | Kansas City | B29 Education | $6.7M | 1 |
| The Stanley H Durwood Foundation CO The Greater KC Community Foundation | Kansas City | T70 Philanthropy, Voluntarism & Grantmaking Foundations | $6.7M | 1 |
| REGENCY MANAGEMENT INC | Cape Girardeau | L200 Housing & Shelter | $6.7M | 1 |
| THE COLLEGE SCHOOL ASSOCIATION | Webster Groves | — | $6.7M | 2 |
