| COLE COUNTY RESIDENTIAL | Jefferson City | F34Z Mental Health & Crisis Intervention | $6.9M | 0 |
| ST LOUIS CRISIS NURSERY | St Louis | — | $6.9M | 3 |
| BOYS AND GIRLS CLUBS OF | Springfield | — | $6.9M | 2 |
| TRUMAN STATE UNIVERSITY FOUNDATION | Kirksville | B114 Education | $6.9M | 5 |
| BIOGENERATOR | St Louis | U50 Science & Technology | $6.9M | 7 |
| INTERNATIONAL ASSOCIATION OF ASSESSING | Kansas City | — | $6.8M | 5 |
| CALVARY UNIVERSITY | Kansas City | — | $6.8M | 5 |
| URBAN SPROUTS | University City | P33 Human Services | $6.8M | 1 |
| CAPITAL CITY AREA COUNCIL FOR | Jefferson City | B28Z Education | $6.8M | 2 |
| BOYS AND GIRLS CLUBS OF WEST CENTRAL | Sedalia | O23Z Youth Development | $6.8M | 0 |
| Stray Rescue of St Louis | Saint Louis | D200 Animal-Related | $6.8M | 2 |
| OAKHILL DAY SCHOOL | Gladstone | — | $6.8M | 1 |
| THE FUND FOR KIPP ST LOUIS | St Louis | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $6.8M | 1 |
| AMERICAN HEREFORD ASSOCIATION | Kansas City | — | $6.8M | 4 |
| COMMUNITY NETWORK FOR BEHAVIORAL | Kansas City | F300 Mental Health & Crisis Intervention | $6.7M | 1 |
| MID-STATES ORGANIZED CRIME | Springfield | I60L Crime & Legal-Related | $6.7M | 4 |
| KANSAS CITY GIRLS PREPARATORY ACADEMY | Kansas City | B29 Education | $6.7M | 1 |
| EMPLOYMENT CONNECTION | St Louis | — | $6.7M | 3 |
| The Stanley H Durwood Foundation CO The Greater KC Community Foundation | Kansas City | T70 Philanthropy, Voluntarism & Grantmaking Foundations | $6.7M | 1 |
| National Association of Basketball Coaches | Kansas City | — | $6.7M | 4 |
| REGENCY MANAGEMENT INC | Cape Girardeau | L200 Housing & Shelter | $6.7M | 1 |
| THE COLLEGE SCHOOL ASSOCIATION | Webster Groves | — | $6.7M | 2 |
| CATHOLIC CHARITIES OF KANSAS CITY - | Kansas City | P20Z Human Services | $6.7M | 2 |
| NURSES FOR NEWBORNS | Maplewood | P99Z Human Services | $6.7M | 3 |
| KIDS ACROSS AMERICA | Branson | X20 Religion-Related | $6.7M | 3 |
| SPECIAL OLYMPICS MISSOURI INC | Jefferson City | — | $6.7M | 2 |
| TEAMSTERS LOCAL UNION NO 688 | St Louis | — | $6.7M | 8 |
| CHILD DAY CARE ASSOCIATION OF ST LOUIS | St Louis | P33L Human Services | $6.7M | 1 |
| HILL FOUNDATION | Saint Louis | — | $6.6M | 4 |
| DISABILITY RESOURCE ASSOCIATION INC | Festus | P20 Human Services | $6.6M | 0 |
| NAT ASSOC OF ELECTRICAL DISTRIBUTORS | St Louis | S11 Community Improvement & Capacity Building | $6.6M | 4 |
| RUNG FOUNDATION INC | St Louis | P20 Human Services | $6.6M | 1 |
| KABUL NURSING HOME INC | Cabool | E910 Health Care | $6.6M | 1 |
| Missourians for Constitutional Freedom | Saint Louis | — | $6.6M | 1 |
| LUTHERAN BIBLE TRANSLATORS INC | Concordia | X20Z Religion-Related | $6.6M | 2 |
| THE FRANCIS FAMILY FOUNDATION | Kansas City | — | $6.5M | 0 |
| ALTON IBEWNECA HEALTH AND WELFARE PLAN | St Louis | Y43 Mutual & Membership Benefit | $6.5M | 0 |
| THE CHANTICLEER CHARITABLE TRUST | Saint Louis | — | $6.5M | 2 |
| MISSOURI ASSOCIATION OF REALTORS | Columbia | — | $6.5M | 3 |
| ARCHCITY DEFENDERS | St Louis | I80 Crime & Legal-Related | $6.5M | 3 |
| AMERICAN ASSOCIATION OF BIOANALYSTS | St Louis | — | $6.5M | 7 |
| HAWTHORN FOUNDATION | Jefferson City | — | $6.4M | 1 |
| ATLAS PUBLIC SCHOOLS | Saint Louis | B29 Education | $6.4M | 1 |
| WOMENS CHRISTIAN ASSOCIATION OF KANSAS CITY MISSOURI | Kansas City | E910 Health Care | $6.4M | 4 |
| ST LOUIS LABORERS VACATION FUND | St Louis | — | $6.4M | 0 |
| TRUMAN MEDICAL CENTER CHARITABLE FOUNDATION | Kansas City | E110 Health Care | $6.3M | 3 |
| BETHESDA HEALTH GROUP INC | St Louis | P750 Human Services | $6.3M | 14 |
| INCARNATE WORD ACADEMY | Saint Louis | B20B Education | $6.3M | 2 |
| HILLCREST PLATTE COUNTY | Riverside | L41 Housing & Shelter | $6.3M | 0 |
| Builders Association of Kansas City | Kansas City | — | $6.3M | 8 |
