| NURSES FOR NEWBORNS | Maplewood | P99Z Human Services | $6.7M | 3 |
| MADISON COUNTY COUNCIL FOR DEVELOPMENTALLY DISABLED INC | Fredericktown | P82Z Human Services | $6.7M | 1 |
| KIDS ACROSS AMERICA | Branson | X20 Religion-Related | $6.7M | 3 |
| TEAMSTERS LOCAL UNION NO 688 | St Louis | — | $6.7M | 8 |
| GOWER CONVALESCENT CENTER INC | Gower | E91Z Health Care | $6.7M | 1 |
| NORTHEAST INDEPENDENT LIVING SERVICES | Hannibal | Z99 Unknown | $6.7M | 0 |
| CHILD DAY CARE ASSOCIATION OF ST LOUIS D/B/A UNITED 4 CHILDREN | St Louis | P33L Human Services | $6.7M | 1 |
| THE SHELDON ARTS FOUNDATION | Saint Louis | A610 Arts, Culture & Humanities | $6.6M | 2 |
| RUNG FOUNDATION INC | St Louis | P20 Human Services | $6.6M | 1 |
| DISABILITY RESOURCE ASSOCIATION INC | Festus | P20 Human Services | $6.6M | 1 |
| KABUL NURSING HOME INC | Cabool | E910 Health Care | $6.6M | 1 |
| Missourians for Constitutional Freedom | Saint Louis | — | $6.6M | 1 |
| LUTHERAN BIBLE TRANSLATORS INC | Concordia | X20Z Religion-Related | $6.6M | 2 |
| HILL FOUNDATION WELLS FARGO BANK NA | Saint Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $6.5M | 3 |
| THE FRANCIS FAMILY FOUNDATION | Kansas City | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $6.5M | 0 |
| ALTON IBEWNECA HEALTH AND WELFARE PLAN | St Louis | Y43 Mutual & Membership Benefit | $6.5M | 0 |
| THE CHANTICLEER CHARITABLE TRUST | Saint Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $6.5M | 2 |
| WOMENS CHRISTIAN ASSOCIATION OF KANSAS CITY MISSOURI | Kansas City | E910 Health Care | $6.5M | 3 |
| BARNARD FREE SKIN AND CANCER HOSPITAL | St Louis | E24Z Health Care | $6.5M | 10 |
| CATHOLIC CHARITIES FOUNDATION | St Louis | — | $6.5M | 4 |
| ARCHCITY DEFENDERS | St Louis | I80 Crime & Legal-Related | $6.5M | 3 |
| AMERICAN ASSOCIATION OF BIOANALYSTS | St Louis | — | $6.5M | 7 |
| SPECIAL OLYMPICS MISSOURI INC | Jefferson City | — | $6.4M | 2 |
| BREILING JEAN CHARITABLE FOUNDATION | Saint Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $6.4M | 1 |
| HAWTHORN FOUNDATION | Jefferson City | — | $6.4M | 1 |
| Love Columbia Corp Love Columbia | Columbia | P20 Human Services | $6.4M | 0 |
| ATLAS PUBLIC SCHOOLS | Saint Louis | B29 Education | $6.4M | 1 |
| NORTHEAST MISSOURI AREA AGENCY ON AGING | Kirksville | P81Z Human Services | $6.4M | 1 |
| NAT ASSOC OF ELECTRICAL DISTRIBUTORS EDUCATION & RESEARCH FOUNDATION INC | St Louis | S11 Community Improvement & Capacity Building | $6.4M | 4 |
| KANSAS CITY AREA DEVELOPMENT COUNCIL | Kansas City | S41 Community Improvement & Capacity Building | $6.4M | 10 |
| ST LOUIS LABORERS VACATION FUND | St Louis | — | $6.4M | 0 |
| ERIC P & EVELYN E NEWMAN CHARITABLE FOUNDATION DTD 8/1/2013 | Saint Louis | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $6.3M | 0 |
| TRUMAN MEDICAL CENTER CHARITABLE FOUNDATION | Kansas City | E110 Health Care | $6.3M | 3 |
| INCARNATE WORD ACADEMY | Saint Louis | B20B Education | $6.3M | 2 |
| ASCENSION VIA CHRISTI PROPERTY SERVICES INC | St Louis | — | $6.3M | 3 |
| Builders Association of Kansas City | Kansas City | — | $6.3M | 8 |
| BIG BROTHERS BIG SISTERS OF EASTERN MISSOURI | Saint Louis | — | $6.3M | 5 |
| THE KRANZBERG ARTS FOUNDATION | St Louis | A20 Arts, Culture & Humanities | $6.3M | 1 |
| GOETZ CREDIT UNION | St Joseph | — | $6.3M | 3 |
| PREVENTED | St Louis | F21Z Mental Health & Crisis Intervention | $6.2M | 3 |
| MEDS & FOOD FOR KIDS | St Louis | Q33 International, Foreign Affairs & National Security | $6.2M | 1 |
| NCHOF INC | St Louis | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $6.2M | 1 |
| OPERATING ENGINEERS LOCAL 101 VACATION PLAN | Kansas City | — | $6.2M | 1 |
| SAINT LOUIS COUNSELING INC | Fenton | — | $6.2M | 4 |
| BOARD OF TRUSTEES SOUTHERN ILLINOIS ELECTRICAL RETIREE WELFARE PLAN | St Louis | — | $6.2M | 0 |
| Mothers Refuge | Independence | P450 Human Services | $6.2M | 1 |
| COMLOQUOY ROBERT AND SARA S CHAR FD | Saint Louis | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $6.2M | 1 |
| VETERANS OF FOREIGN WARS FOUNDATION | Kansas City | J20I Employment | $6.2M | 1 |
| UNITED SOCCER COACHES ASSOCIATION | Kansas City | N99Z Recreation & Sports | $6.2M | 5 |
| MISSOURI CORN MERCHANDISING COUNCIL | Jefferson City | — | $6.2M | 1 |
