| COMMUNITY ASSISTANCE AND MENTORING PROGRAM | Hopkins | S20 Community Improvement & Capacity Building | $786k | 0 |
| Kappa Sigma Fraternity Housing Corp of Columbia | Columbia | — | $786k | 0 |
| EMPLOYERS NETWORK | Spartanburg | S31Z Community Improvement & Capacity Building | $786k | 1 |
| JUST SAY SOMETHING INC | Greenville | P400 Human Services | $785k | 1 |
| ST STEPHEN BOARD OF | St Stephen | — | $785k | 0 |
| SPARTANBURG RECREATIONAL FACILITIES | Spartanburg | S20 Community Improvement & Capacity Building | $783k | 3 |
| GREENVILLE LITERACY ASSOCIATION | Greenville | B920 Education | $783k | 1 |
| JOSEPH J SCHOTT FOUNDATION | Mount Pleasant | — | $781k | 3 |
| AIKEN ASSOCIATION OF REALTORS | Aiken | Y03 Mutual & Membership Benefit | $781k | 0 |
| Arthur Bailey Ministries International | Fort Mill | X20 Religion-Related | $781k | 1 |
| Boys & Girls Clubs of the Lakelands | Greenwood | O21 Youth Development | $779k | 1 |
| Trinity Classical Academy of Summerville | Summerville | B20 Education | $779k | 4 |
| Lighthouse for Life | Irmo | — | $778k | 2 |
| BIG SHOTS GLOBAL | North Myrtle Beach | — | $777k | 0 |
| Beza Fund Inc | Taylors | Q32 International, Foreign Affairs & National Security | $776k | 0 |
| SC INTERNATIONAL TRADE CONFERENCE | Mount Pleasant | — | $776k | 0 |
| MCCORMICK COUNTY HOUSING FOR AGINGINC | McCormick | — | $775k | 0 |
| NORTH MYRTLE BEACH CHRISTIAN SCHOOL | Longs | B20Z Education | $775k | 0 |
| FRATERNUS INC | Pickens | O50 Youth Development | $773k | 5 |
| HOME BUILDERS ASSOCIATION OF SC | Columbia | — | $773k | 1 |
| Bluffton Community Soup Kitchen | Bluffton | P20 Human Services | $773k | 1 |
| FEED & SEED CO | Greenville | B60 Education | $771k | 0 |
| JUNIOR JAZZ FOUNDATION INC | Hilton Head Island | A60 Arts, Culture & Humanities | $771k | 0 |
| MISSION HOPE FOUNDATION | Columbia | X40 Religion-Related | $771k | 4 |
| Impact Change | Rock Hill | K30 Food, Agriculture & Nutrition | $769k | 0 |
| HISTORIC BEAUFORT FOUNDATION | Beaufort | A82Z Arts, Culture & Humanities | $768k | 1 |
| HUMANE SOCIETY OF | North Myrtle Beach | D20 Animal-Related | $767k | 0 |
| CHAPIN EAGLE CLUB | Chapin | — | $766k | 0 |
| HILTON HEAD ISLAND FOUNDATION TO | Bluffton | N50 Recreation & Sports | $765k | 1 |
| RIZE Prevention Inc | Simpsonville | — | $765k | 1 |
| IAAM SUPPORT ORGANIZATION | Charleston | A11 Arts, Culture & Humanities | $764k | 6 |
| LCL ROCKSTARS INC | Chester | O19 Youth Development | $764k | 0 |
| PUBLIC WORKS ARTS CENTER | Summerville | J11 Employment | $764k | 0 |
| SIXTH DISTRICT OMEGA PSI PHI FRATERNITY | Columbia | — | $763k | 0 |
| DIGNITY HOUSING ASSOCIATION INC | Columbia | L200 Housing & Shelter | $761k | 0 |
| REAL CHAMPIONS INC | Ridgeland | O51 Youth Development | $759k | 1 |
| JUNIOR LEAGUE OF GREENVILLE INC | Greenville | S810 Community Improvement & Capacity Building | $759k | 1 |
| Museum & Gallery Inc | Greenville | A510 Arts, Culture & Humanities | $759k | 1 |
| HOLY CITY CHRISTIAN ACADEMY | Huger | B24 Education | $758k | 0 |
| FRESHWATER COAST | Abbeville | S20 Community Improvement & Capacity Building | $758k | 0 |
| BROOKLAND ACADEMY CHILD DEVELOPMENT CENTER | Columbia | B21 Education | $758k | 1 |
| FOSTERING FOSTER ANIMAL RESCUE | Camden | D20 Animal-Related | $757k | 0 |
| LEGACY ADVANCEMENT | Greenville | B12 Education | $757k | 0 |
| Kanguka | Mount Pleasant | — | $756k | 0 |
| RIVER HILLS EMERGENCY SQUAD INC | Lake Wylie | E620 Health Care | $755k | 3 |
| EMERSON ROSE HEART FOUNDATION | Clemson | E12 Health Care | $755k | 1 |
| JASPER COUNTY COUNCIL ON AGING INC | Ridgeland | P81Z Human Services | $753k | 1 |
| ENOUGH IS ENOUGH | Mount Pleasant | I99Z Crime & Legal-Related | $752k | 2 |
| CHARLESTON AREA THERAPEUTIC | Johns Island | E50Z Health Care | $751k | 1 |
| SUMTER COUNTY MUSEUM FOUNDATION | Sumter | — | $751k | 0 |
