| PURE INC | Bentonville | P12 Human Services | $31.6M | 0 |
| HEALTHY CONNECTIONS INC | Mena | E70 Health Care | $31.2M | 6 |
| HARRIET AND WARREN STEPHENS FAMILY | Little Rock | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $31M | 0 |
| CENTERS FOR YOUTH AND FAMILIES INC | Little Rock | P40 Human Services | $30.8M | 11 |
| Town Branch Foundation | Bentonville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $30.8M | 1 |
| BILL HILLARY & CHELSEA CLINTON | Little Rock | E70 Health Care | $30.5M | 11 |
| Baptist Health Hospitals | Little Rock | E20 Health Care | $30.4M | 9 |
| ARKANSAS CONNECTIONS ACADEMY INC | Bentonville | B99 Education | $30M | 0 |
| NORTHWEST ARKANSAS FOOD BANK | Lowell | — | $29.9M | 2 |
| THE JESUS FUND (SECTION 501(C)(3) | Little Rock | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $29.5M | 1 |
| SOUTH CENTRAL ARKANSAS ELECTRIC | Arkadelphia | — | $29.3M | 15 |
| EPISCOPAL COLLEGIATE SCHOOL FOUNDATION | Little Rock | B11 Education | $29.2M | 0 |
| BentonvilleBella Vista Trailblazers | Bentonville | N30 Recreation & Sports | $28.7M | 2 |
| Ouachita Electric Cooperative Corporation | Camden | — | $28.1M | 18 |
| BRADLEY COUNTY MEDICAL CENTER | Warren | E22Z Health Care | $28M | 6 |
| 1ST CHOICE HEALTHCARE INC | Corning | — | $27.5M | 12 |
| George's Inc Medical Plan & Trust | Springdale | — | $27.3M | 0 |
| Washington Regional Medical System Welfare Benefit Plan | Fayetteville | Y43 Mutual & Membership Benefit | $27.1M | 1 |
| LYON COLLEGE | Batesville | B420 Education | $26.4M | 4 |
| Philander Smith College | Little Rock | B420 Education | $25.3M | 7 |
| Magnolia Regional Health System INC | Magnolia | E20 Health Care | $25.1M | 10 |
| THE FOOD BANK OF NORTHEAST ARKANSAS | Jonesboro | P60 Human Services | $24.9M | 1 |
| UNITED CEREBRAL PALSY OF CENT ARK INC | Little Rock | G23Z Diseases, Disorders & Medical Disciplines | $24.9M | 2 |
| LITTLE ROCK CHRISTIAN ACADEMY INC | Little Rock | B20Z Education | $24.2M | 4 |
| RIVER VALLEY PRIMARY CARE SERVICES | Ratcliff | E30 Health Care | $23.9M | 6 |
| Western Arkansas Counseling and Guidance Center Inc | Fort Smith | F32Z Mental Health & Crisis Intervention | $23.8M | 10 |
| PULASKI ACADEMY | Little Rock | B200 Education | $23.2M | 5 |
| UNITED METHODIST BEHAVIORAL HEALTH | Little Rock | E24 Health Care | $22.9M | 3 |
| AREA AGENCY ON AGING OF SOUTHEAST AR INC | Pine Bluff | P810 Human Services | $22.8M | 2 |
| ARKANSAS EARLY LEARNING INC | Jonesboro | P20 Human Services | $22.7M | 7 |
| WINDGATE CHARITABLE FOUNDATION INC | Little Rock | T12 Philanthropy, Voluntarism & Grantmaking Foundations | $22.6M | 3 |
| JOHN ED CHAMBERS MEMORIAL HOSPITAL INC | Danville | E220 Health Care | $22.5M | 7 |
| CHICOT MEMORIAL MEDICAL CENTER | Lake Village | E22 Health Care | $22.1M | 9 |
| ACCESS GROUP INC | Little Rock | B00Z Education | $22M | 1 |
| RICH MOUNTAIN ELECTRIC COOPERATIVE INC | Mena | — | $21.9M | 16 |
| ST ANTHONY'S HOSPITAL ASSOCIATION | Morrilton | — | $21.8M | 10 |
| BUTTERFIELD TRAIL VILLAGE | Fayetteville | P750 Human Services | $21.6M | 6 |
| LAWRENCE MEMORIAL HEALTH FOUNDATION INC | Walnut Ridge | E20 Health Care | $21.5M | 6 |
| Wend II Inc | Bentonville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $21.4M | 0 |
| THADEN SCHOOL | Bentonville | B25 Education | $21.1M | 10 |
| Drew Memorial Hospital Inc | Monticello | E20 Health Care | $20.8M | 8 |
| CHILDREN'S MUSEUM OF NW ARKANSAS | Bentonville | A50 Arts, Culture & Humanities | $20.4M | 2 |
| DELTA MEMORIAL HOSPITAL | Dumas | E22Z Health Care | $20.3M | 9 |
| MERCY HOSPITAL BERRYVILLE | Berryville | E22 Health Care | $20.1M | 15 |
| Mississippi County Arkansas Economic Opportunity Commission Inc | Blytheville | — | $20.1M | 1 |
| FRIENDSHIP ASPIRE ARKANSAS INC | Little Rock | B29 Education | $19.9M | 6 |
| CITY CORPORATION | Russellville | — | $19.7M | 1 |
| ST BERNARDS COMMUNITY HOSPITAL | Wynne | E22 Health Care | $19.6M | 6 |
| ARKANSAS CHILDREN'S MEDICAL GROUP PLLC | Little Rock | E31 Health Care | $19.6M | 12 |
| Dardanelle Regional LLC | Dardanelle | E22 Health Care | $19.5M | 9 |
