| DENVER JEWISH DAY SCHOOL | Denver | B25 Education | $11.7M | 2 |
| International Brotherhood of Teamsters | Denver | — | $11.7M | 13 |
| LA CLINICA TEPEYAC | Denver | E30 Health Care | $11.7M | 9 |
| PUEBLO SCHOOL FOR ARTS AND SCIENCES | Pueblo | B29 Education | $11.6M | 1 |
| PYRAMID MODEL CONSORTIUM | Fort Collins | B99 Education | $11.6M | 0 |
| COMMUNITY HEALTH PROVIDER ALLIANCE | Denver | P20 Human Services | $11.5M | 5 |
| ROUNDUP FELLOWSHIP | Denver | P700 Human Services | $11.5M | 4 |
| JUNIOR ACHIEVEMENT USA HEALTH & WELFARE BENEFIT PLAN TRUST | Colorado Springs | — | $11.5M | 4 |
| LA RAZA SERVICES INC | Denver | — | $11.5M | 5 |
| ALPHA PHI INTERNATIONAL FRATERNITY | Denver | — | $11.5M | 2 |
| UPTOWN COMMUNITY HEALTH CENTER INC | Denver | E32 Health Care | $11.4M | 6 |
| UTILITY NOTIFICATION CENTER OF COLORADO | Golden | — | $11.4M | 7 |
| TENNYSON CENTER FOR CHILDREN AT | Denver | P30 Human Services | $11.3M | 5 |
| AXL Academy Charter School | Aurora | B24 Education | $11.3M | 2 |
| WELD LEGACY FOUNDATION | Greeley | E110 Health Care | $11.2M | 3 |
| The Word for the World USA | Colorado Springs | X20 Religion-Related | $11.2M | 2 |
| BIEBER FAMILY FOUNDATION | Denver | — | $11.2M | 0 |
| PIKES PEAK COMMUNITY FOUNDATION | Colorado Springs | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $11.2M | 4 |
| FLAGSTAFF ACADEMY | Longmont | B29 Education | $11.2M | 1 |
| NOCO HUMANE | Loveland | D200 Animal-Related | $11.2M | 2 |
| UNIVERSITY PREPARATORY SCHOOLS | Denver | B29 Education | $11.2M | 2 |
| FUND FOR THE NEW SCHOOL | Boulder | — | $11.2M | 6 |
| ADDENBROOKE CLASSICAL ACADEMY INC | Lakewood | B20 Education | $11.1M | 0 |
| VALLEY COUNTRY CLUB | Centennial | — | $11.1M | 6 |
| Cherry Hills Christian School | Highlands Ranch | B24 Education | $11.1M | 3 |
| JEWISH COMMUNITY CENTERS OF DENVER | Denver | P28Z Human Services | $11.1M | 4 |
| EDUCATION COMMISSION OF THE STATES | Northglenn | B00F Education | $11M | 7 |
| St Francis Nursing Center Inc | Colorado Springs | — | $11M | 3 |
| COTTONWOOD COMMUNITY ALTERNATIVES | Englewood | P70Z Human Services | $10.9M | 5 |
| COMMUNITY FOUNDATION BOULDER COUNTY | Boulder | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $10.9M | 3 |
| ARABIAN HORSE ASSOCIATION | Greenwood Village | — | $10.8M | 4 |
| UNION COLONY SCHOOLS | Greeley | B29 Education | $10.8M | 0 |
| Western Resource Advocates | Boulder | I83Z Crime & Legal-Related | $10.8M | 10 |
| COLORADO VISITING NURSE ASSOCIATION | Denver | E92B Health Care | $10.8M | 6 |
| COLORADO CHAUTAUQUA ASSOCIATION | Boulder | Z99Z Unknown | $10.8M | 3 |
| DENVER METRO CHAMBER OF COMMERCE | Denver | — | $10.8M | 9 |
| MERCY HOUSING CALWEST | Denver | L20Z Housing & Shelter | $10.7M | 15 |
| THE GEOLOGICAL SOCIETY OF AMERICA | Boulder | U03 Science & Technology | $10.7M | 7 |
| SHEILA FORTUNE FOUNDATION INC | Boulder | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.7M | 1 |
| NORTH COLORADO HEALTH ALLIANCE | Evans | E60 Health Care | $10.7M | 1 |
| HIGH PLAINS COMMUNITY HEALTH CENTER | Lamar | E21 Health Care | $10.7M | 5 |
| RAISE THE FUTURE | Denver | P310 Human Services | $10.7M | 7 |
| Villages Ltd | Fort Collins | — | $10.6M | 2 |
| Sabrina Merage Foundation | Englewood | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.6M | 0 |
| KIDS CROSSING | Colorado Springs | P320 Human Services | $10.6M | 3 |
| CROSSPURPOSE | Denver | S21 Community Improvement & Capacity Building | $10.6M | 7 |
| UNITED WAY OF LARIMER COUNTY | Fort Collins | T70 Philanthropy, Voluntarism & Grantmaking Foundations | $10.5M | 5 |
| World Compass Academy | Castle Rock | B29 Education | $10.5M | 1 |
| COLORADO YOUTH CORPS ASSOCIATION | Denver | C12 Environment | $10.5M | 1 |
| CENTER FOR IMPROVING VALUE IN | Denver | H05 Medical Research | $10.5M | 7 |
