| THE CEDAR RAPIDS COUNTRY CLUB | Cedar Rapids | — | $7.8M | 5 |
| ALGONA COMMUNITY SCHOOL FOUNDATION | Algona | — | $7.8M | 0 |
| GREATER SIOUX COMMUNITY HEALTH | Sioux Center | E320 Health Care | $7.8M | 7 |
| BIOCONNECT IOWA | Des Moines | S43 Community Improvement & Capacity Building | $7.7M | 2 |
| BAUM HARMON MERCY HOSPITAL | Primghar | E220 Health Care | $7.7M | 10 |
| MID-AMERICA AGRI-INDUSTRIES VEBA | Sioux City | — | $7.6M | 0 |
| CENT CREDIT UNION | Mason City | — | $7.6M | 1 |
| GREATER DES MOINES CONVENTION & VISITORS | Des Moines | — | $7.6M | 4 |
| BRAVO GREATER DES MOINES INC | Des Moines | A122 Arts, Culture & Humanities | $7.6M | 1 |
| GIRL SCOUTS OF GREATER IOWA | Urbandale | — | $7.5M | 4 |
| DES MOINES AREA RELIGIOUS COUNCIL | Des Moines | P60 Human Services | $7.5M | 1 |
| ANAWIM HOUSING INC | Des Moines | — | $7.5M | 3 |
| SIOUX CENTER CHRISTIAN SCHOOL | Sioux Center | B24Z Education | $7.5M | 0 |
| IOWA HIGH SCHOOL ATHLETIC ASSOCIATION | Boone | B114 Education | $7.5M | 5 |
| CEDAR RAPIDS SHEET METAL WORKERS LOCAL | Cedar Rapids | — | $7.4M | 0 |
| IOWA ODD FELLOWS AND ORPHANS HOME CORP | Mason City | P70Z Human Services | $7.4M | 3 |
| WEILER FOUNDATION | Knoxville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $7.4M | 0 |
| TELCO TRIAD COMMUNITY CREDIT UNION | Sioux City | — | $7.4M | 1 |
| CREATIVE COMMUNITY OPTIONS INC | Johnston | P20Z Human Services | $7.3M | 1 |
| THE GERDIN CHARITABLE FOUNDATION | North Liberty | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $7.3M | 0 |
| Emmaus Bible College | Dubuque | — | $7.3M | 6 |
| CAMP COURAGEOUS OF IOWA | Monticello | P820 Human Services | $7.2M | 1 |
| MANY HANDS FOR HAITI | Pella | P60 Human Services | $7.2M | 0 |
| SIOUXLAND HUMAN INVESTMENT PARTNERSHIP | Sioux City | P20 Human Services | $7.2M | 2 |
| CONNECTIONS AREA AGENCY ON AGING | Council Bluffs | P81Z Human Services | $7.2M | 2 |
| REGIONAL DEVELOPMENT AUTHORITY | Davenport | — | $7.2M | 1 |
| International Messengers | Clear Lake | X21Z Religion-Related | $7.2M | 5 |
| MILESTONES AREA AGENCY ON AGING | Davenport | P81Z Human Services | $7.2M | 3 |
| COMMUNITY HEALTH FREE CLINIC | Cedar Rapids | E30 Health Care | $7.2M | 1 |
| ISU VETERINARY SERVICES CORPORATION | Des Moines | B11 Education | $7.2M | 11 |
| OPPORTUNITIES UNLIMITED | Sioux City | Z99Z Unknown | $7.2M | 1 |
| WESTHAVEN COMMUNITY MINISTRY OF THE | Boone | E910 Health Care | $7.1M | 3 |
| CROW VALLEY GOLF CLUB | Davenport | — | $7.1M | 4 |
| Dubuque County Historical Society | Dubuque | A82Z Arts, Culture & Humanities | $7.1M | 2 |
| BLACK HAWK-GRUNDY MENTAL HEALTH CENTER | Waterloo | F32 Mental Health & Crisis Intervention | $7.1M | 6 |
| RSM US FOUNDATION | Davenport | B82 Education | $7M | 0 |
| IOWA JEWISH SENIOR LIFE CENTER | Des Moines | E91 Health Care | $7M | 1 |
| PROTEUS INC | Des Moines | J200 Employment | $7M | 2 |
| OSCEOLA COUNTY RURAL WATER SYSTEM | May City | — | $7M | 10 |
| SCIENCE CENTER OF IOWA | Des Moines | A570 Arts, Culture & Humanities | $7M | 3 |
| HILLCREST HOME | Sumner | — | $7M | 1 |
| LAKE PANORAMA ASSOCIATION | Panora | — | $6.9M | 11 |
| THE YOUNG MEN'S CHRISTIAN ASSOCIATION OF THE CEDAR RAPIDS METROPOLITAN AREA | Cedar Rapids | P27Z Human Services | $6.9M | 2 |
| ALLEN HEALTH SYSTEMS INC | Waterloo | — | $6.9M | 6 |
| ELMCREST COUNTRY CLUB | Cedar Rapids | — | $6.8M | 1 |
| AEGON TRANSAMERICA FOUNDATION | Cedar Rapids | — | $6.8M | 0 |
| World Food Prize Foundation | Urbandale | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $6.8M | 2 |
| UNITED WAY OF EAST CENTRAL IOWA | Cedar Rapids | T70 Philanthropy, Voluntarism & Grantmaking Foundations | $6.8M | 2 |
| DAVENPORT COUNTRY CLUB | Pleasant Valley | — | $6.8M | 4 |
| ST LUKE'S HEALTH CARE FOUNDATION | Cedar Rapids | E110 Health Care | $6.8M | 1 |
