| TAMAQUA AREA COMMUNITY PARTNERSHIP | Tamaqua | S20 Community Improvement & Capacity Building | $4.5M | 1 |
| THE MARCELLUS SHALE COALITION | Pittsburgh | S41 Community Improvement & Capacity Building | $4.5M | 8 |
| LEHIGH VALLEY INDUSTRIAL PARK INC | Bethlehem | — | $4.5M | 2 |
| CROI FOUNDATION | Pittsburgh | H81 Medical Research | $4.5M | 0 |
| Landmark Home Health Care Services Inc | Pittsburgh | E92Z Health Care | $4.5M | 1 |
| KEYSTONE VOCATIONAL SERVICES INC | Hermitage | J20 Employment | $4.5M | 2 |
| Children First PA | Philadelphia | P010 Human Services | $4.5M | 1 |
| HOPE WALKS INC | York Springs | Q33 International, Foreign Affairs & National Security | $4.5M | 2 |
| Independence Blue Cross Foundation | Philadelphia | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.5M | 0 |
| COGNITIVE BEHAVIORAL SERVICES INC | Philadelphia | F60 Mental Health & Crisis Intervention | $4.5M | 5 |
| USW CRUCIBLE RETIREES HEALTH AND WELFARE TRUST | Pittsburgh | Y44 Mutual & Membership Benefit | $4.5M | 2 |
| United States Tennis Association- Middle States Section | Valley Forge | — | $4.5M | 4 |
| GOLD MEDAL KARATE INC | Philadelphia | N40 Recreation & Sports | $4.5M | 1 |
| Assessment & Treatment Alternatives Inc | Philadelphia | F300 Mental Health & Crisis Intervention | $4.5M | 5 |
| THE BARRA FOUNDATION INC | Philadelphia | — | $4.5M | 1 |
| INTERNATIONAL SEAFOOD SUSTAINABILITY FOUNDATION INC | Pittsburgh | D30 Animal-Related | $4.5M | 5 |
| UNIVERSITY DENTAL HEALTH SERVICES INC | Pittsburgh | Z99Z Unknown | $4.5M | 10 |
| CARE & SHARE SHOPPES INC | Souderton | P29 Human Services | $4.5M | 0 |
| HARRISBURG SYMPHONY ASSOCIATION INC | Harrisburg | A690 Arts, Culture & Humanities | $4.5M | 2 |
| CUMBERLAND AREA ECONOMIC DEVELOPMENT CORPORATION | Mechanicsburg | S30 Community Improvement & Capacity Building | $4.5M | 4 |
| THE TUTTLEMAN FOUNDATION | Erwinna | — | $4.5M | 2 |
| PHILADELPHIA CHINATOWN DEVELOPMENT CORPORATION | Philadelphia | S31Z Community Improvement & Capacity Building | $4.5M | 1 |
| FEDERATION OF NEIGHBORHOOD CENTERS | Philadelphia | O500 Youth Development | $4.5M | 3 |
| TRANSPLANT FOUNDATION | Philadelphia | G110 Diseases, Disorders & Medical Disciplines | $4.5M | 7 |
| THE CREFELD SCHOOL | Philadelphia | — | $4.5M | 1 |
| WASHINGTON DRUG & ALCOHOL COMMISSION | Washington | F20 Mental Health & Crisis Intervention | $4.4M | 2 |
| DAVID S SHAPIRA FOUNDATION | Pittsburgh | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $4.4M | 0 |
| Garden of Health Inc | North Wales | P99 Human Services | $4.4M | 0 |
| JUVENILE LAW CENTER | Philadelphia | I80Z Crime & Legal-Related | $4.4M | 8 |
| CRAWFORD COUNTY MENTAL HEALTH AWARENESS PROGRAM INC | Meadville | F22Z Mental Health & Crisis Intervention | $4.4M | 1 |
| HELLO NEIGHBOR | Pittsburgh | P20 Human Services | $4.4M | 1 |
| Vida Charter School | Gettysburg | B29 Education | $4.4M | 1 |
| PLEA | Homestead | F30Z Mental Health & Crisis Intervention | $4.4M | 6 |
| ERIE YACHT CLUB | Erie | — | $4.4M | 2 |
| COMMUNITY COLLEGE OF PHILADELPHIA FOUNDATION | Philadelphia | B12 Education | $4.4M | 1 |
| LOCALLY GROWN | Pittsburgh | P28 Human Services | $4.4M | 1 |
| PAXTON STREET HOME BENEVOLENT SOCIETY | Harrisburg | P80Z Human Services | $4.4M | 1 |
| PENNSYLVANIA ENVIRONMENTAL COUNCIL INC | Pittsburgh | C010 Environment | $4.4M | 6 |
| WESTMORELAND COUNTRY CLUB | Export | — | $4.4M | 0 |
| The Childrens Aid Home Programs of Somerset County Inc | Somerset | P31 Human Services | $4.4M | 1 |
| POWER FOR GOOD FOUNDATION | Chester | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $4.4M | 1 |
| PHILADELPHIA ACADEMY OF SCHOOL LEADERS INC | Philadelphia | B90 Education | $4.4M | 5 |
| MARS HOLDINGS INC | Cranberry Township | L20 Housing & Shelter | $4.4M | 3 |
| YOUNG MEN'S CHRISTIAN ASSOCIATION OF FRANKLIN AND GROVE CITY | Franklin | P27Z Human Services | $4.4M | 1 |
| WYOMING VALLEY AIDS COUNCIL | Wilkes Barre | G81 Diseases, Disorders & Medical Disciplines | $4.4M | 0 |
| KEY FOUNDATION | Wellsville | Z99Z Unknown | $4.4M | 0 |
| Eisenhower Exchange Fellowships Incorporated | Philadelphia | Q230 International, Foreign Affairs & National Security | $4.4M | 7 |
| LEHIGH COUNTY AGRICULTURAL SOCIETY | Allentown | — | $4.4M | 5 |
| STRING THEORY SCHOOLS | Philadelphia | B900 Education | $4.4M | 10 |
| Marlboro School of Music Inc | Philadelphia | A6E0 Arts, Culture & Humanities | $4.4M | 2 |