| ACCESS TO HEALTHCARE NETWORK INC | Reno | E99 Health Care | $20.2M | 4 |
| SAM SCHMIDT FOUNDATION | Las Vegas | E50 Health Care | $20M | 3 |
| HGR FAMILY FOUNDATION INC | Incline Village | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $20M | 0 |
| CLARK COUNTY FIREFIGHTERS LOCAL 1908 SEC FUND | Las Vegas | — | $20M | 0 |
| COMMUNITIES IN SCHOOLS OF NEVADA INC | Las Vegas | P30Z Human Services | $19.5M | 4 |
| JOHNSON ROBERT K FOUNDATION-MAIN | Las Vegas | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $19.3M | 2 |
| Nevada Museum of Art | Reno | A510 Arts, Culture & Humanities | $19.1M | 8 |
| WALKER BASIN CONSERVANCY | Reno | C32 Environment | $18.9M | 1 |
| HOROWITZ FAMILY FOUNDATION | Las Vegas | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $18.6M | 0 |
| SOUTH LYON HEALTH CENTER INC | Yerington | E22Z Health Care | $17.8M | 8 |
| WESTCARE GULFCOAST FLORIDA INC | Las Vegas | F22 Mental Health & Crisis Intervention | $17.4M | 2 |
| SPORTS LEADERSHIP AND MANAGEMENT ACADEMY | Las Vegas | B29 Education | $17.2M | 2 |
| NORTHERN NEVADA BUILDING & CONSTRUC | Reno | — | $17.2M | 0 |
| Renown Health Foundation | Reno | — | $16.9M | 6 |
| THE CYNTHIA LAKE CHARITABLE TRUST | Reno | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $16.7M | 0 |
| CYRUS TANG FOUNDATION | Las Vegas | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $16.3M | 3 |
| CAMERON CHARITABLE TRUST | Las Vegas | — | $16.2M | 1 |
| BLIND CENTER OF NEVADA INC | Las Vegas | — | $16.1M | 2 |
| The Summerlin Council | Las Vegas | — | $15.9M | 0 |
| Renown Transitional Care Services | Reno | E400 Health Care | $15.7M | 5 |
| TANG INDUSTRIES INC EMPLOYEE WELFARE | Las Vegas | — | $15.5M | 0 |
| UA LOCAL 350 HEALTH WELFARE AND | Reno | — | $15.1M | 0 |
| INTERNATIONAL BROTHERHOOD OF ELECTRICAL | Las Vegas | — | $15.1M | 27 |
| CULINARY ACADEMY OF LAS VEGAS | North Las Vegas | B30 Education | $15.1M | 9 |
| Las Vegas Metro Employee Benefit TR | Las Vegas | Y44 Mutual & Membership Benefit | $15.1M | 0 |
| CONSTRUCTION INDUSTRY & LABORERS VACATION AND DISABILITY PLAN | Las Vegas | — | $14.6M | 0 |
| Boys Town Nevada Inc | Las Vegas | P70 Human Services | $14.4M | 3 |
| SUNRISE CHILDRENS FOUNDATION | Las Vegas | Z99Z Unknown | $14.3M | 5 |
| COMMUNITY SERVICES AGENCY | Reno | — | $14.3M | 7 |
| THE BOYD FOUNDATION | Las Vegas | — | $14.2M | 7 |
| Summerlin North Community Association | Las Vegas | — | $14.1M | 0 |
| DOROTHY LEMELSON FOUNDATION | Reno | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $14M | 3 |
| UNITED WAY OF SOUTHERN NEVADA | Las Vegas | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $14M | 9 |
| OASIS ACADEMY CHARTER SCHOOL | Fallon | B29 Education | $13.9M | 0 |
| WILLIAM N PENNINGTON FOUNDATION | Reno | T19 Philanthropy, Voluntarism & Grantmaking Foundations | $13.8M | 4 |
| INTERNATIONAL CULTURAL EXCHANGE SERVICES | Henderson | Q220 International, Foreign Affairs & National Security | $13.8M | 5 |
| LAKE MEAD CHRISTIAN MINISTRIES | Henderson | Z99Z Unknown | $13.8M | 2 |
| LAS VEGAS FIREFIGHTERS HEALTH & WELFARE TRUST | Las Vegas | — | $13.7M | 0 |
| NATIONAL COUNCIL OF JUVENILE & FAMILY | Reno | I50C Crime & Legal-Related | $13.7M | 7 |
| OPPORTUNITY 180 | Las Vegas | B90 Education | $13.6M | 2 |
| NORTHERN NEVADA LABORERS HEALTH AND | Reno | — | $13.6M | 0 |
| SPREAD THE WORD NEVADA | Henderson | O50 Youth Development | $13.3M | 1 |
| CHRISTIAN MISSIONARY SCHOLARSHIP FOUND | Las Vegas | — | $13.3M | 0 |
| WESTSTAR CREDIT UNION | Las Vegas | — | $13.3M | 7 |
| GUIDANCECARE CENTER INC | Las Vegas | — | $13.1M | 4 |
| FINANCIAL HORIZONS CREDIT UNION | Hawthorne | — | $13.1M | 2 |
| NEVADA BAR FOUNDATION | Las Vegas | I80 Crime & Legal-Related | $12.9M | 0 |
| PLUMBERS AND PIPEFITTERS UNION LOCAL 525 | Las Vegas | — | $12.9M | 10 |
| ANDRE AGASSI FOUNDATION FOR EDUCATION | Las Vegas | P120 Human Services | $12.9M | 2 |
| HOPELINK OF SOUTHERN NEVADA | Henderson | L21Z Housing & Shelter | $12.8M | 2 |
