| GOSPEL MUSIC ASSOCIATION TRADE ORGANZIATION | Franklin | — | $5.4M | 1 |
| SOUTHERN ALLIANCE FOR CLEAN ENERGY | Knoxville | C35 Environment | $5.4M | 1 |
| ALCOHOLISM SERVICES OF KNOXVILLE INC DBA MIDWAY REHABILITATION CENTER | Knoxville | F22Z Mental Health & Crisis Intervention | $5.4M | 2 |
| TENNESSEE ASSOCIATION OF REALTORS INC | Nashville | — | $5.4M | 1 |
| SCOTT APPALACHIAN INDUSTRIES INC | Huntsville | N20 Recreation & Sports | $5.4M | 1 |
| MEMPHIS RIVER PARKS PARTNERSHIP INC | Memphis | S30 Community Improvement & Capacity Building | $5.4M | 4 |
| KAPPA DELTA FOUNDATION INCORPORATED | Memphis | B820 Education | $5.4M | 0 |
| Creative Discovery Museum | Chattanooga | A520 Arts, Culture & Humanities | $5.4M | 1 |
| MAKE-A-WISH FOUNDATION OF THE MID-SOUTH INC | Memphis | E86Z Health Care | $5.4M | 1 |
| Masters International Ministries USA | Limestone | X99 Religion-Related | $5.4M | 0 |
| Women In Cyber Security | Cookeville | B03 Education | $5.4M | 1 |
| THE CMA FOUNDATION | Nashville | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $5.4M | 3 |
| TENNESSEE ASSOCIATION OF UTILITY DISTRICTS | Murfreesboro | S41 Community Improvement & Capacity Building | $5.4M | 7 |
| THE AIM CENTER INC | Chattanooga | P820 Human Services | $5.4M | 1 |
| KNOXVILLE AREA CHAMBER PARTNERSHIP | Knoxville | — | $5.4M | 1 |
| THE HEALING TRUST FORMERLY BAPTIST HEALING HOSPITAL TRUST | Nashville | E12 Health Care | $5.3M | 1 |
| Aristevi Foundation | Old Hickory | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 1 |
| TENNESSEE WALKING HORSE NATIONAL | Shelbyville | — | $5.3M | 1 |
| THE TRANSPORTATION MANAGEMENT ASSOC | Franklin | P99Z Human Services | $5.3M | 4 |
| NASHVILLE SOFTWARE SCHOOL INC | Nashville | B28 Education | $5.3M | 7 |
| KNOXVILLE SYMPHONY SOCIETY INCORPORATED | Knoxville | A690 Arts, Culture & Humanities | $5.3M | 4 |
| TRACTOR SUPPLY COMPANY FOUNDATION | Brentwood | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 0 |
| PROMISE ACADEMY INC | Memphis | B29 Education | $5.3M | 2 |
| MEMORIAL FOUNDATION INC | Madison | E210 Health Care | $5.3M | 2 |
| Methodist Healthcare Foundation | Memphis | E120 Health Care | $5.3M | 4 |
| AMERICAN ASSOCIATION FOR LABORATORY ANIMAL SCIENCE | Memphis | D034 Animal-Related | $5.3M | 5 |
| Exchange Club - Carl Perkins Center for the Prevention of Child Abuse Inc | Jackson | P40N Human Services | $5.3M | 2 |
| Nautilus Management Inc | Memphis | B83 Education | $5.2M | 2 |
| SOUTHERN CONSERVATION CORP | McMinnville | C27 Environment | $5.2M | 0 |
| NEIL AND ELIZABETH GRIFFIN CHARITABLE FOUNDATION | Cordova | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.2M | 0 |
| Holston Habitat for Humanity Inc | Kingsport | — | $5.2M | 1 |
| BRAINERD BAPTIST SCHOOL | Chattanooga | B24 Education | $5.2M | 1 |
| BE A HELPING HAND | Nashville | J22 Employment | $5.2M | 1 |
| KINGSPORT PRESS CU | Kingsport | — | $5.2M | 1 |
| BRIGHTSTONE INC | Franklin | B28 Education | $5.2M | 1 |
| USW HRA FUND | Nashville | — | $5.2M | 4 |
| MORGAN COUNTY HEALTH COUNCIL INC | Wartburg | E32Z Health Care | $5.2M | 8 |
| BIG BROTHERSBIG SISTERS OF MIDDLE TN | Nashville | O30Z Youth Development | $5.2M | 4 |
| Rural Life Foundation Inc | Savannah | — | $5.1M | 6 |
| MEMPHIS GRIZZLIES PREPARATORY CHARTER SCHOOL INC | Memphis | B25 Education | $5.1M | 1 |
| Ronald McDonald House Charities of Memphis Inc | Memphis | G30Z Diseases, Disorders & Medical Disciplines | $5.1M | 2 |
| BICENTENNIAL VOLUNTEERS INCORPORATED | Knoxville | T40Z Philanthropy, Voluntarism & Grantmaking Foundations | $5.1M | 4 |
| DELTA HUMAN RESOURCE AGENCY | Covington | S200 Community Improvement & Capacity Building | $5.1M | 0 |
| INTERNATIONAL BROTHERHOOD OF ELECTRICAL LOCAL UNION NUMBER 175 | Chattanooga | — | $5.1M | 6 |
| Eastern Eight Community Development Corporation Inc | Johnson City | L122 Housing & Shelter | $5.1M | 2 |
| THE REFUGE CENTER FOR COUNSELING INC | Franklin | P40 Human Services | $5.1M | 1 |
| TENNESSEE RIVER GORGE TRUST TENNESSEE RIVER GORGE TRUST | Chattanooga | C320 Environment | $5.1M | 1 |
| PROVIDENCE SENIOR LIVING INC | Cleveland | L22 Housing & Shelter | $5.1M | 0 |
| Laurelbrook Sanitarium and School Inc | Dayton | — | $5.1M | 5 |
| THE RELEVATE GROUP INC | Franklin | X03 Religion-Related | $5M | 4 |
