| COLORADO PET PANTRY | Boulder | D20 Animal-Related | $3.5M | 1 |
| THREE BIRDS ALLIANCE | Aurora | P430 Human Services | $3.5M | 1 |
| THE GROWHAUS | Denver | — | $3.5M | 1 |
| WESTERN COLORADO HEALTHCARE | Grand Junction | B99M Education | $3.5M | 3 |
| Prospect Academy of Colorado | Arvada | B29 Education | $3.5M | 1 |
| PROTECTING COLORADOS ENVIRONMENT ECONOMY | Denver | — | $3.5M | 1 |
| COLORADO CENTER FOR NURSING EXCELLE | Denver | J05 Employment | $3.5M | 6 |
| BROWN BAG MINISTRIES INC | Lakewood | P60 Human Services | $3.5M | 1 |
| The Place | Colorado Springs | P20 Human Services | $3.5M | 3 |
| TELLURIDE MOUNTAIN SCHOOL INC | Telluride | B20 Education | $3.5M | 0 |
| WOMEN'S PROFESSIONAL RODEO ASSOCIAT | Colorado Springs | — | $3.5M | 18 |
| BOOK TRUST | Denver | B24 Education | $3.5M | 4 |
| DORNICK FOUNDATION INC | Woody Creek | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $3.5M | 0 |
| FORT COLLINS CONVENTION | Fort Collins | — | $3.5M | 3 |
| LP BROWN FOUNDATION | Boulder | — | $3.5M | 0 |
| BIG BROTHERS BIG SISTERS OF | Denver | O31 Youth Development | $3.5M | 4 |
| COLORADO GARDEN SHOW INC | Lakewood | C60 Environment | $3.5M | 13 |
| PIKES PEAK STATE COLLEGE | Colorado Springs | B41Z Education | $3.4M | 3 |
| FOCUS POINTS FAMILY RESOURCE CENTER | Denver | P40 Human Services | $3.4M | 1 |
| COLORADO CHAMBER OF COMMERCE | Denver | — | $3.4M | 7 |
| THE LONGMONT COMMUNITY FOUNDATION | Longmont | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $3.4M | 1 |
| SAFEHOUSE PROGRESSIVE ALLIANCE FOR | Boulder | P43Z Human Services | $3.4M | 1 |
| PUBLIC MEDIA COMPANY | Boulder | A34 Arts, Culture & Humanities | $3.4M | 5 |
| WILD BEAR NATURE CENTER | Nederland | C30 Environment | $3.4M | 2 |
| PARADIGMONE INC | Aurora | F22 Mental Health & Crisis Intervention | $3.4M | 1 |
| LOU ENGLE MINISTRIES | Colorado Springs | X20 Religion-Related | $3.4M | 3 |
| FREEDOM SERVICE DOGS INC | Englewood | P800 Human Services | $3.4M | 0 |
| ASIAN PACIFIC DEVELOPMENT CENTER OF COLORADO | Aurora | P840 Human Services | $3.4M | 1 |
| BOOKCLIFF COUNTRY CLUB | Grand Junction | — | $3.4M | 1 |
| Henry P and Susan C Crowell Trust | Colorado Springs | — | $3.4M | 8 |
| THE FOUNDATION STEAMBOAT SPRINGS WINTER | Steamboat Springs | N68 Recreation & Sports | $3.4M | 0 |
| COLORADO ASSOCIATION OF TRANSIT AGENCIES | Denver | — | $3.4M | 1 |
| FOOTHILLS ART CENTER INC | Golden | A400 Arts, Culture & Humanities | $3.4M | 1 |
| Ryobi Foundation | Carbondale | T23 Philanthropy, Voluntarism & Grantmaking Foundations | $3.4M | 2 |
| LAMB PROMOTION RESEARCH | Greenwood Village | — | $3.4M | 1 |
| COALITIONS & COLLABORATIVES INC | Denver | C30 Environment | $3.4M | 1 |
| English in Action | Basalt | B60 Education | $3.4M | 1 |
| Redline | Denver | A40 Arts, Culture & Humanities | $3.4M | 1 |
| THE KBK FOUNDATION | Denver | — | $3.4M | 0 |
| NNF FOUNDATION | Centennial | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $3.4M | 0 |
| COMMUNITY ENTERPRISE DEVELOPMENT | Aurora | P51 Human Services | $3.3M | 1 |
| COLORADO SHEET METAL WORKERS | Denver | — | $3.3M | 3 |
| POSADA | Pueblo | L410 Housing & Shelter | $3.3M | 1 |
| SERVE 6 8 | Loveland | P20 Human Services | $3.3M | 2 |
| Sachs Foundation | Colorado Springs | B82 Education | $3.3M | 5 |
| PROFESSIONAL RODEO COWBOYS ASSOCIATION INC | Colorado Springs | — | $3.3M | 41 |
| THE ATTAINMENT NETWORK | Denver | B01 Education | $3.3M | 3 |
| Pueblo Community College Foundation | Pueblo | B41I Education | $3.3M | 1 |
| ELEPHANT CIRCLE | Palisade | I80 Crime & Legal-Related | $3.3M | 2 |
| THE MATTHEWS HOUSE | Fort Collins | P50 Human Services | $3.3M | 1 |
