| WARREN COUNTY PATHFINDERS | Warrenton | P82Z Human Services | $5.6M | 0 |
| THE CENTER FOR AUTISM EDUCATION | St Peters | B28 Education | $5.6M | 1 |
| BOYS HOPE GIRLS HOPE | Saint Louis | P300 Human Services | $5.6M | 6 |
| Jane Phillips Nowata Hospital Inc | St Louis | E22 Health Care | $5.6M | 8 |
| LUTHERAN DEVELOPMENT GROUP | Saint Louis | L21 Housing & Shelter | $5.6M | 1 |
| MISSOURI BAPTIST CHILDREN'S HOME | Bridgeton | X99 Religion-Related | $5.6M | 3 |
| SHIRKEY DIVERSIFIED HEALTH SERVICES | Richmond | E91 Health Care | $5.5M | 1 |
| CHESTERFIELD HOCKEY ASSOCIATION | Chesterfield | N68Z Recreation & Sports | $5.5M | 3 |
| INTERCO CHARITABLE TRUST | St Louis | T90Z Philanthropy, Voluntarism & Grantmaking Foundations | $5.5M | 5 |
| ECONOMIC DEVELOPMENT CORPORATION OF KANSAS CITY MISSOURI | Kansas City | — | $5.5M | 6 |
| RAPHA HOUSE INTERNATIONAL INC | Joplin | I72 Crime & Legal-Related | $5.5M | 0 |
| APEX OIL COMPANY CHARITABLE FOUNDATION | Clayton | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $5.5M | 0 |
| Alexian Brothers Center for Mental Health | St Louis | F30Z Mental Health & Crisis Intervention | $5.5M | 4 |
| VARIETY THE CHILDRENS CHARITY OF ST LOUIS | Saint Louis | — | $5.5M | 2 |
| SSM HEALTH FOUNDATION - ST LOUIS | St Louis | — | $5.5M | 10 |
| HELPING HAND OF GOODWILL INDUSTRIES EXT EMP SHELTERED WORKSHOP | Kansas City | — | $5.5M | 6 |
| FARMHOUSE FOUNDATION | Kansas City | — | $5.4M | 1 |
| Moms for America Inc | Branson | P20 Human Services | $5.4M | 3 |
| Kansas City Hospice Foundation | Kansas City | E24Z Health Care | $5.4M | 3 |
| GRAND RIVER AREA FAMILY YMCA INC | Chillicothe | — | $5.4M | 3 |
| AGRICULTURE FUTURE OF AMERICA | Kansas City | O52 Youth Development | $5.4M | 2 |
| MISSOURI FARM BUREAU FEDERATION | Jefferson City | — | $5.4M | 19 |
| MISSOURI SOYBEAN ASSOCIATION | Jefferson City | — | $5.4M | 6 |
| DE LA SALLE EDUCATION CENTER | Kansas City | — | $5.4M | 1 |
| BRIDGE STRUCTURAL & ORNAMENTAL IRON WORKERS INTL ASSN LOCAL 10 | Kansas City | — | $5.4M | 17 |
| NEW HAVEN CARE CENTER INC | New Haven | — | $5.4M | 1 |
| JOBONE | Independence | — | $5.4M | 1 |
| UNITED ASSOCIATION OF JOURNEYMAN & APPRENTICE PLUMBERS LOCAL UNION 8 | Kansas City | — | $5.4M | 14 |
| THE WILSON SCHOOL | St Louis | B250 Education | $5.4M | 1 |
| CITYSERVE INTERNATIONAL | Springfield | A23 Arts, Culture & Humanities | $5.4M | 3 |
| EVERETT AND GENEVA SUGARBAKER FOUNDATION | Saint Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $5.4M | 0 |
| HEYMAN-DAIGLE FAMILY FOUNDATION | St Louis | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.4M | 0 |
| MEDICA CENTRAL HEALTH PLAN | St Louis | E70 Health Care | $5.3M | 12 |
| Encounter Ministry Inc | Roach | X99 Religion-Related | $5.3M | 1 |
| AREA AGENCY ON AGING REGION X | Joplin | P81 Human Services | $5.3M | 3 |
| LABORERS UNION LOCAL 110 | St Louis | — | $5.3M | 9 |
| THE ESR PULITZER FOUNDATION | St Louis | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 0 |
| LEAST OF THESE INC | Ozark | P60 Human Services | $5.3M | 1 |
| MISSOURI SOUTHERN FOUNDATION | Joplin | B42I Education | $5.3M | 0 |
| Shelter KC | Kansas City | L410 Housing & Shelter | $5.3M | 1 |
| STAGES ST LOUIS | Chesterfield | — | $5.3M | 2 |
| VOLT CREDIT UNION | Springfield | — | $5.3M | 3 |
| GENETIC AUTISM ALLIANCE | Jefferson City | T01 Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 0 |
| GATEWAY GLOBAL AMERICAN YOUTH & BUSINESS ALLIANCE INC GATEWAY GLOBAL AMERICAN YOUTH & BUSINESS ALLIANCE ACAD | Saint Louis | B01 Education | $5.3M | 0 |
| OPERATING ENGINEERS LOCAL NO 101 APPRENTICESHIP FUND | Platte City | — | $5.3M | 6 |
| NEW HEIGHTS CHRISTIAN ACADEMY | Joplin | B200 Education | $5.3M | 0 |
| THE STEPHEN F & CAMILLA T BRAUER CHARITABLE TRUST | Chesterfield | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $5.3M | 0 |
| WILLIAM P INGERSOLL TRUST C | Clayton | O19 Youth Development | $5.3M | 1 |
| SPAY & NEUTER KANSAS CITY D/B/A PET RESOURCE CENTER OF KANSAS CITY | Kansas City | D20 Animal-Related | $5.3M | 1 |
| MISSOURI INCUTECH FOUNDATION | Rolla | S32Z Community Improvement & Capacity Building | $5.2M | 5 |
