| Lurie Children's Pediatric Anesthesia Associates | Chicago | — | $14.2M | 13 |
| AMERICAN ASSOCIATION OF ENDODONTISTS | Chicago | S41 Community Improvement & Capacity Building | $14.1M | 29 |
| INSTITUTE OF REAL ESTATE MANAGEMENT | Chicago | S47Z Community Improvement & Capacity Building | $14.1M | 11 |
| Silver Cross Health System | New Lenox | E020 Health Care | $14.1M | 11 |
| R J SAMULSKI INNOVATION FOUNDATION INC | Chicago | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $14.1M | 0 |
| U F C W UNIONS & EMPLOYERS MIDWEST | Downers Grove | — | $14.1M | 4 |
| THE COVE SCHOOL INC | Northbrook | B28Z Education | $14.1M | 7 |
| CARWYTHEN CHARITABLE TRUST | Chicago | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $14.1M | 0 |
| BLEEDING & CLOTTING DISORDERS INSTITUTE | Peoria | E50 Health Care | $14M | 8 |
| University Place Inc | Lemont | E91 Health Care | $14M | 7 |
| J S FRANK FOUNDATION | Deerfield | — | $14M | 0 |
| Western Illinois University Foundation | MacOmb | B43I Education | $14M | 3 |
| INTERNATIONAL ASSOCIATION OF MACHINISTS & AEROSPACE WORKERS | Elk Grove Village | — | $14M | 36 |
| EUREKA COLLEGE | Eureka | B420 Education | $14M | 3 |
| OLD TOWN SCHOOL OF FOLK MUSIC | Chicago | A6E0 Arts, Culture & Humanities | $14M | 6 |
| THE WILLIAM H MINER FOUNDATION | Chicago | T900 Philanthropy, Voluntarism & Grantmaking Foundations | $14M | 3 |
| REFUGEEONE | Chicago | X20Z Religion-Related | $13.9M | 2 |
| FEATHERFIST | Chicago | P20Z Human Services | $13.9M | 0 |
| Foundation of the American College of | Chicago | B600 Education | $13.9M | 9 |
| Centers for New Horizons Inc | Chicago | — | $13.9M | 1 |
| AFFORDABLE HOUSING DEVELOPMENT FUND INC | Rockford | L20 Housing & Shelter | $13.8M | 3 |
| UNITED CREDIT UNION | Chicago | W61 Public & Societal Benefit | $13.8M | 3 |
| THE ARLINGTON OF NAPLES | Arlington Heights | — | $13.8M | 4 |
| ASSOCIATION FOR CORPORATE GROWTH - GROUP | Chicago | — | $13.8M | 17 |
| Illiana Financial Credit Union | Calumet City | W61 Public & Societal Benefit | $13.8M | 4 |
| TABOR HILLS HEALTH CARE FACILITY INC | Naperville | F20Z Mental Health & Crisis Intervention | $13.8M | 19 |
| AMERICAN NUCLEAR SOCIETY INCORPORATED | Westmont | U03 Science & Technology | $13.8M | 8 |
| LUNGEVITY FOUNDATION INC | Chicago | H124 Medical Research | $13.8M | 9 |
| RESIDENTIAL OPTIONS INC | Alton | L200 Housing & Shelter | $13.7M | 2 |
| By The Hand Club For Kids | Chicago | — | $13.7M | 4 |
| NORTH AMERICAN ASSOCIATION OF FOOD | Chicago | — | $13.7M | 4 |
| TAZEWELL COUNTY RESOURCE CENTERS INC | Pekin | P820 Human Services | $13.7M | 4 |
| Illinois Assistive Technology Program | Springfield | T99Z Philanthropy, Voluntarism & Grantmaking Foundations | $13.7M | 1 |
| CLARA ABBOTT FOUNDATION | Abbott Park | Y20 Mutual & Membership Benefit | $13.7M | 2 |
| American Association of Neurosurgeons | Rolling Meadows | G030 Diseases, Disorders & Medical Disciplines | $13.6M | 10 |
| PLEASANT VIEW LUTHER HOME INC | Ottawa | L22 Housing & Shelter | $13.6M | 5 |
| Motorola Solutions Foundation | Chicago | — | $13.6M | 0 |
| THE FUND FOR THE BOYS & GIRLS CLUBS | Chicago | O11 Youth Development | $13.6M | 0 |
| GALESBURG COMMUNITY FOUNDATION | Galesburg | T99 Philanthropy, Voluntarism & Grantmaking Foundations | $13.6M | 2 |
| FOUNDATION FOR SARCOIDOSIS RESEARCH | Chicago | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $13.6M | 2 |
| MAKE-A-WISH FOUNDATION OF ILLINOIS INC | Chicago | — | $13.6M | 8 |
| NORTH LAWNDALE COLLEGE PREPARATORY | Chicago | B25 Education | $13.6M | 6 |
| GLAZING EMPLOYERS & GLAZIERS UNION | Lyons | — | $13.6M | 5 |
| PARK PLACE CHRISTIAN COMMUNITY | Tinley Park | P75 Human Services | $13.5M | 4 |
| HEALTHCARE ALTERNATIVE SYSTEMS INC | Chicago | F220 Mental Health & Crisis Intervention | $13.5M | 3 |
| REAL CLEAR FOUNDATION | Northbrook | B82 Education | $13.5M | 2 |
| COMMUNITY ALTERNATIVES UNLIMITED | Chicago | — | $13.5M | 7 |
| INDIAN HILL CLUB | Winnetka | — | $13.5M | 7 |
| STALEY CREDIT UNION | Decatur | — | $13.5M | 4 |
| ACCLIVUS INC | Chicago | E70 Health Care | $13.5M | 4 |
