| HOPE HOUSE OF COLORADO | Arvada | P20 Human Services | $6.1M | 2 |
| ALTA VISTA CENTER FOR AUTISM | Lakewood | G84 Diseases, Disorders & Medical Disciplines | $6.1M | 1 |
| Denver Islamic Education Center Inc | Aurora | — | $6.1M | 0 |
| AMERICAN ASSOCIATION OF | Denver | S41 Community Improvement & Capacity Building | $6.1M | 7 |
| COLORADO FUTURE FARMERS OF AMERICA | Greeley | O52Z Youth Development | $6.1M | 0 |
| LOVELAND HABITAT FOR HUMANITY INC | Loveland | — | $6.1M | 2 |
| COLORADO ASSOCIATION OF REALTORS | Englewood | — | $6.1M | 2 |
| THE GALENA FOUNDATION | Denver | T20J Philanthropy, Voluntarism & Grantmaking Foundations | $6.1M | 0 |
| Response - Help for Survivors of Domestic Violence & Sexual Assault | Basalt | P43Z Human Services | $6.1M | 1 |
| NATIONAL ARCHERY ASSOCIATION OF THE US | Colorado Springs | N030 Recreation & Sports | $6M | 6 |
| WALDORF SCHOOL ASSOCIATION OF | Boulder | — | $6M | 4 |
| The Haven Foundation | Canon City | X20 Religion-Related | $6M | 2 |
| Community Connections Inc | Durango | P820 Human Services | $6M | 3 |
| WHALE ROCK COUNTRY CLUB INC | Morrison | — | $6M | 5 |
| ASPEN CHAMBER RESORT ASSOCIATION INC | Aspen | — | $6M | 5 |
| WATERSHED SCHOOL INC | Boulder | B28 Education | $6M | 1 |
| HELLE FAMILY FOUNDATION | Edwards | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $6M | 0 |
| Legacy Academy | Elizabeth | B24 Education | $5.9M | 1 |
| COMPASS MONTESSORI SECONDARY SCHOOL | Golden | B29 Education | $5.9M | 1 |
| Ultimate Players Association | Colorado Springs | N60 Recreation & Sports | $5.9M | 6 |
| HUNGER FREE COLORADO | Denver | K30 Food, Agriculture & Nutrition | $5.9M | 2 |
| COLORADO LEAGUE OF CHARTER SCHOOLS | Denver | B99 Education | $5.9M | 3 |
| COLORADO LIBRARY CONSORTIUM | Centennial | — | $5.9M | 2 |
| STURM FAMILY FOUNDATION | Denver | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $5.9M | 0 |
| INSTITUTE FOR BRAIN POTENTIAL | Parker | B99 Education | $5.9M | 1 |
| The St Francis Center | Denver | — | $5.9M | 5 |
| INTERNATIONAL WILDERNESS LEADERSHIP | Boulder | — | $5.9M | 2 |
| ASPEN CENTER FOR ENVIRONMENTAL STUDIES | Aspen | C600 Environment | $5.9M | 3 |
| The Residences at Eaton Senior | Lakewood | L210 Housing & Shelter | $5.9M | 3 |
| Development Associates International | Colorado Springs | X83 Religion-Related | $5.9M | 2 |
| KIDS FIRST HEALTH CARE | Commerce City | E32 Health Care | $5.9M | 3 |
| SPECIALIZED ALTERNATIVES FOR | Fort Collins | P20 Human Services | $5.9M | 5 |
| I Have A Dream Foundation | Boulder | B80Z Education | $5.9M | 1 |
| INDEPENDENCE ACADEMY | Grand Junction | B29 Education | $5.9M | 1 |
| WILD PLUM CENTER FOR YOUNG CHILDREN | Longmont | B21 Education | $5.9M | 1 |
| TEACHING TREE EARLY CHILDHOOD | Fort Collins | — | $5.9M | 1 |
| USA TAEKWONDO INC | Colorado Springs | N70 Recreation & Sports | $5.8M | 2 |
| THE HADANOU COLLECTIVE | Denver | B90 Education | $5.8M | 1 |
| Opportunity Education Foundation | Littleton | Q33 International, Foreign Affairs & National Security | $5.8M | 1 |
| CREDIT UNION OF THE ROCKIES | Golden | — | $5.8M | 10 |
| Quality Health Network | Grand Junction | E02 Health Care | $5.8M | 15 |
| Vail Christian School Inc | Edwards | B25 Education | $5.8M | 2 |
| Eagle County Charter Academy | Edwards | B20 Education | $5.8M | 3 |
| THE UNITED STATES OLYMPIC AND PARALYMPIC ENDOWMENT | Colorado Springs | N120 Recreation & Sports | $5.8M | 4 |
| MomCo Global Inc | Denver | P400 Human Services | $5.8M | 2 |
| Denver Broncos Foundation | Englewood | T50J Philanthropy, Voluntarism & Grantmaking Foundations | $5.8M | 0 |
| NEXTFIFTY INITIATIVE | Denver | E19 Health Care | $5.8M | 1 |
| CHILDREN'S DIABETES FOUNDATION | Aurora | G800 Diseases, Disorders & Medical Disciplines | $5.7M | 4 |
| TELLURIDEMONTROSE REGIONAL AIR | Telluride | S41 Community Improvement & Capacity Building | $5.7M | 1 |
| Aircraft Mechanics Faternal Associa | Englewood | J40 Employment | $5.7M | 7 |
