| AMON CARTER MUSEUM OF WESTERN ART | Fort Worth | A510 Arts, Culture & Humanities | $23.5M | 9 |
| BROWNSVILLE COMMUNITY HEALTH CLINIC CORP | Brownsville | — | $23.5M | 9 |
| Transitional Learning Center at Galveston | Houston | F300 Mental Health & Crisis Intervention | $23.5M | 14 |
| VASHISHT FOUNDATION | Arlington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $23.4M | 0 |
| AMARILLO AREA FOUNDATION INC | Amarillo | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $23.4M | 5 |
| HABITAT FOR HUMANITY OF SAN ANTONIO INC | San Antonio | L20Z Housing & Shelter | $23.4M | 8 |
| INFORMED CONSENT ACTION NETWORK | Austin | E60 Health Care | $23.2M | 9 |
| Hospice of Wichita Falls Inc | Wichita Falls | P740 Human Services | $23.2M | 5 |
| BATTLESHIP TEXAS FOUNDATION | Houston | A50 Arts, Culture & Humanities | $23.2M | 4 |
| MIDLAND CHRISTIAN SCHOOL | Midland | B20 Education | $23.2M | 6 |
| GALVESTON COUNTY FOOD BANK | Texas City | P60 Human Services | $23.2M | 1 |
| FELLOWSHIP OF ISRAEL RELATED MINISTRIES INC | Grapevine | X20 Religion-Related | $23.2M | 0 |
| Methodist-CDI | Dallas | E30 Health Care | $23.2M | 6 |
| DELTA DELTA DELTA NATIONAL HOUSE CORP - GROUP RETURN | Dallas | — | $23.2M | 0 |
| THE BETA FOUNDATION | Houston | B29 Education | $23.2M | 6 |
| PRATHAM USA | Houston | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $23.1M | 7 |
| DAN L DUNCAN FOUNDATION | Houston | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $23.1M | 0 |
| AUSTIN TRINITY SCHOOL | Austin | B99 Education | $23.1M | 7 |
| ALBERT & BESSIE MAE KRONKOSKY CHARITABLE | Dallas | — | $23M | 2 |
| HHI Services Inc | San Antonio | P82 Human Services | $23M | 7 |
| HEALTH SERVICES OF NORTH TEXAS INC | Denton | G81Z Diseases, Disorders & Medical Disciplines | $23M | 11 |
| AUSTIN COUNTRY CLUB | Austin | — | $22.9M | 9 |
| COVENANT KIDS INC | Arlington | P31 Human Services | $22.9M | 7 |
| BIG BROTHERS BIG SISTERS LONE STAR | Dallas | O310 Youth Development | $22.9M | 8 |
| SCHOOL OF EXCELLENCE IN EDUCATION DBA LEGACY TRADITIONAL SCHOOLS-TEXAS | San Antonio | B99Z Education | $22.8M | 1 |
| Texas Health Back Care | Dallas | E99 Health Care | $22.8M | 12 |
| Christus Health Strategic Growth | Irving | E12 Health Care | $22.8M | 6 |
| CHARTER FOR CHARITY INC | Dallas | E62 Health Care | $22.7M | 0 |
| TEXOMA COMMUNITY CREDIT UNION | Wichita Falls | — | $22.7M | 10 |
| Union Gospel Mission of Tarrant County | Fort Worth | — | $22.7M | 7 |
| COMMUNITIES IN SCHOOLS OF CENTRAL TEXAS | Austin | B032 Education | $22.7M | 5 |
| ALCUIN SCHOOL | Dallas | B200 Education | $22.6M | 7 |
| SW TEXAS HOUSING SERVICE RES INC | Tomball | L80 Housing & Shelter | $22.6M | 0 |
| Pioneer Bible Translators | Dallas | X20 Religion-Related | $22.6M | 11 |
| Dairy Max Inc | Grand Prairie | — | $22.6M | 25 |
| The USAA Foundation Inc | San Antonio | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $22.6M | 0 |
| AMERICAN GI FORUM NATIONAL VETERANS OUTREACH PROGRAM INC | San Antonio | — | $22.5M | 0 |
| HOUSING BENEFITS PLAN CO JOHN POPE HOUSING SOLUTIONS ALLIANCE | Dallas | — | $22.5M | 0 |
| PERRY AND JOYCE JOHNS FOUNDATION | Fort Worth | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $22.5M | 0 |
| TYLER FAMILY CIRCLE OF CARE | Tyler | E300 Health Care | $22.4M | 9 |
| The Priddy Foundation | Wichita Falls | — | $22.4M | 9 |
| HOPE HOSPICE DBA SUNDANCE INN HEALTH CENTER | New Braunfels | P74Z Human Services | $22.3M | 7 |
| BOTANICAL RESEARCH INSTITUTE OF TEXAS INC | Fort Worth | U50 Science & Technology | $22.3M | 5 |
| ALL CHURCH HOME FOR CHILDREN FOUNDATION | Fort Worth | P117 Human Services | $22.3M | 2 |
| MARSHALL FAMILY FOUNDATION | Houston | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $22.3M | 0 |
| TIDEWATER AND BIG BEND FOUNDATION | Houston | A80 Arts, Culture & Humanities | $22.2M | 9 |
| Planned Parenthood Gulf Coast Inc | Houston | E420 Health Care | $22.2M | 12 |
| Promotional Products Association Int'l | Irving | — | $22.2M | 12 |
| COMMUNITIES IN SCHOOLS OF HOUSTON INC | Houston | B94 Education | $22.1M | 4 |
| First Liberty Institute | Plano | R40Z Civil Rights, Social Action & Advocacy | $22.1M | 8 |
