| UNITED WAY OF TARRANT COUNTY | Fort Worth | T70Z Philanthropy, Voluntarism & Grantmaking Foundations | $25.4M | 11 |
| Mother Frances Hospital - Winnsboro | Irving | E20 Health Care | $25.3M | 10 |
| BROOK HOLLOW GOLF CLUB | Dallas | — | $25.3M | 7 |
| SOUTH PLAINS FOOD BANK INC | Lubbock | K31Z Food, Agriculture & Nutrition | $25.3M | 1 |
| MID COAST HEALTH SYSTEM | El Campo | E12 Health Care | $25.3M | 10 |
| CW OPERATING COMPANY INC DBA THE CLUB AT CARLTON WOODS | The Woodlands | N6A Recreation & Sports | $25.2M | 6 |
| SCANLAN FOUNDATION | Houston | P12 Human Services | $25.2M | 2 |
| Innovative Network of Knowledge | San Antonio | O50 Youth Development | $25.2M | 4 |
| Eden Home Inc | New Braunfels | — | $25.1M | 5 |
| Evelyn Rubenstein Jewish Community Center of Houston | Houston | X99Z Religion-Related | $25.1M | 7 |
| Coalition for the Homeless of HoustonHarris County | Houston | L00L Housing & Shelter | $25.1M | 6 |
| WI-FI ALLIANCE | Austin | S41 Community Improvement & Capacity Building | $25.1M | 10 |
| The Cullen Foundation | Houston | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $25M | 3 |
| REFINERY TERMINAL FIRE COMPANY | Corpus Christi | M24 Public Safety, Disaster Preparedness & Relief | $25M | 7 |
| BELLSOUTH CORP HEALTH CARE TRUST - RETIREES | Dallas | — | $25M | 1 |
| COMMUNITIES IN SCHOOLS OF SAN ANTONIO | San Antonio | B95Z Education | $25M | 2 |
| WAYSIDE SCHOOLS | Austin | B99Z Education | $24.9M | 2 |
| EDUCATION SERVICE CENTER REGION II | Corpus Christi | B20B Education | $24.9M | 6 |
| HOT WORKFORCE DEVELOPMENT BOARD INC C/O EDUCATION SERVICE CENTER REGION 12 | Waco | J20 Employment | $24.9M | 1 |
| EMANCIPET INC | Austin | D200 Animal-Related | $24.9M | 9 |
| MAREK FAMILY FOUNDATION | Houston | — | $24.8M | 0 |
| Cumberland Academy | Tyler | — | $24.7M | 1 |
| Aramco US Retiree Welfare Benefit Trust | Houston | — | $24.7M | 0 |
| AMERICAN ACADEMY OF NURSE PRACTITIONERS NATIONAL CERTIFICATION BOARD INC | Austin | E039 Health Care | $24.6M | 16 |
| EDUCATORS CREDIT UNION | Waco | — | $24.5M | 5 |
| Kleinheinz Family Foundation For The Arts And Education | Fort Worth | Z99 Unknown | $24.5M | 2 |
| GREATER AUSTIN PERFORMING ARTS CENTER INC | Austin | A610 Arts, Culture & Humanities | $24.5M | 7 |
| SOUTHERN GATEWAY PUBLIC GREEN FOUNDATION | Dallas | S21 Community Improvement & Capacity Building | $24.4M | 1 |
| NORTHWOOD CLUB | Dallas | — | $24.4M | 7 |
| DALLAS ZOOLOGICAL SOCIETY | Dallas | D115 Animal-Related | $24.3M | 7 |
| UNIVERSITY OF NORTH TEXAS FOUNDATION INC | Denton | T30I Philanthropy, Voluntarism & Grantmaking Foundations | $24.3M | 7 |
| ROYAL OAKS COUNTRY CLUB INC | Dallas | — | $24.3M | 13 |
| BLUE LEARNING | Lewisville | B29 Education | $24.1M | 5 |
| YMCA of Metropolitan Fort Worth | Fort Worth | P270 Human Services | $24.1M | 4 |
| KICKAPOO SPRINGS FOUNDATION | Abilene | T50Z Philanthropy, Voluntarism & Grantmaking Foundations | $24M | 9 |
| THE LEGETT FOUNDATION | Abilene | T50Z Philanthropy, Voluntarism & Grantmaking Foundations | $24M | 9 |
| UNITED TEXAS CREDIT UNION | San Antonio | — | $23.9M | 19 |
| TEXAS MEDICAL ASSOCIATION | Austin | — | $23.9M | 11 |
| SAINT MARY'S HALL | San Antonio | B200 Education | $23.9M | 11 |
| GENESYS WORKS | Keller | B30 Education | $23.9M | 17 |
| HISPANIC ASSOCIATION OF COLLEGES & UNIVERSITIES | San Antonio | B90Z Education | $23.9M | 10 |
| Girl Scouts of San Jacinto Council | Houston | O420 Youth Development | $23.9M | 10 |
| AMERICAN RELIGIOUS TOWN HALL MEETING GROUP RETURN | Dallas | E91Z Health Care | $23.9M | 12 |
| NUESTRA CLINICA DEL VALLE INC | Pharr | — | $23.7M | 7 |
| PEOPLEFUND | Austin | S43 Community Improvement & Capacity Building | $23.7M | 7 |
| Driscoll Children's Hospital Development Foundation | Corpus Christi | T22Z Philanthropy, Voluntarism & Grantmaking Foundations | $23.7M | 8 |
| ASSOCIATION FOR THE ADVANCEMENT OF MEXICAN AMERICANS | Houston | P840 Human Services | $23.6M | 7 |
| ALAMO AREA RESOURCE CENTER INC | San Antonio | G81Z Diseases, Disorders & Medical Disciplines | $23.6M | 3 |
| DARE 2 | Dallas | — | $23.6M | 0 |
| SWISHER ELECTRIC COOPERATIVE INC | Tulia | — | $23.5M | 12 |
