| SANTA BARBARA ZOOLOGICAL FOUNDATION | Santa Barbara | D500 Animal-Related | $21.8M | 8 |
| The Village Family Services Inc | North Hollywood | P70 Human Services | $21.8M | 8 |
| NORTHERN CALIFORNIA BAKERY DRIVERS | Alameda | — | $21.8M | 0 |
| PICHAI FAMILY FOUNDATION | San Francisco | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $21.8M | 0 |
| 10000 DEGREES | San Rafael | B11 Education | $21.8M | 9 |
| Boys Republic | Chino Hills | P300 Human Services | $21.7M | 6 |
| PERENCHIO FOUNDATION | Pasadena | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $21.7M | 2 |
| REDF | San Francisco | T012 Philanthropy, Voluntarism & Grantmaking Foundations | $21.7M | 10 |
| Imaginable Futures Foundation | Redwood City | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $21.7M | 0 |
| SAN FRANCISCO FRIENDS SCHOOL | San Francisco | B20 Education | $21.7M | 8 |
| Homeless Prenatal Program Inc | San Francisco | E99Z Health Care | $21.7M | 6 |
| HOTEL AND RESTAURANT EMPLOYEES | Pleasanton | — | $21.7M | 0 |
| THE LAND TRUST FOR SANTA BARBARA COUNTY | Santa Barbara | C340 Environment | $21.7M | 4 |
| The Laborers Pacific Southwest Regional | Sacramento | J40 Employment | $21.7M | 5 |
| Associated Students Inc California | San Luis Obispo | B80Z Education | $21.6M | 6 |
| American Federation of State County | Oakland | — | $21.6M | 53 |
| FORTY-NINER SHOPS INC | Long Beach | B800 Education | $21.6M | 11 |
| THE INFORMATION & REFERRAL FEDERATION OF | San Gabriel | P00L Human Services | $21.6M | 5 |
| THE AMGEN FOUNDATION INC | Newbury Park | — | $21.6M | 0 |
| THE HEALTH TRUST | San Jose | E120 Health Care | $21.5M | 8 |
| Valley Teen Ranch | Fresno | P70Z Human Services | $21.5M | 1 |
| FAMILY HEALTH CARE CENTERS | Commerce | E42Z Health Care | $21.5M | 8 |
| THE MALOU FOUNDATION | Pasadena | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $21.5M | 0 |
| IMPACT JUSTICE | Oakland | R20 Civil Rights, Social Action & Advocacy | $21.5M | 9 |
| IRVINE ICE FOUNDATION | Corona Del Mar | N31 Recreation & Sports | $21.4M | 1 |
| TOWARD MAXIMUM INDEPENDENCE | San Diego | P53Z Human Services | $21.4M | 9 |
| Proteus Inc | Visalia | J200 Employment | $21.4M | 3 |
| ASSOCIATION FOR SPECIALTY COFFEE | Irvine | — | $21.4M | 10 |
| UNIVERSITY OF THE PEOPLE | Pasadena | B42 Education | $21.4M | 7 |
| AGC OF AMERICA SAN DIEGO CHAPTER INC | San Diego | — | $21.3M | 0 |
| THE REUTLINGER COMMUNITY | Danville | E91Z Health Care | $21.3M | 10 |
| East Bay Agency for Children | Oakland | F32Z Mental Health & Crisis Intervention | $21.3M | 7 |
| ACE CHARTER SCHOOL | San Jose | B29 Education | $21.3M | 7 |
| WESTERN CHRISTIAN SCHOOLS | Upland | B24Z Education | $21.3M | 1 |
| AFTER-SCHOOL ALL-STARS LOS ANGELES | Los Angeles | B99 Education | $21.3M | 1 |
| HARDEN FOUNDATION | Salinas | — | $21.3M | 2 |
| LIFE SKILLS TRAINING & EDUCATIONAL | Sacramento | L20 Housing & Shelter | $21.3M | 0 |
| THRIVE SCHOLARS | Los Angeles | B82 Education | $21.3M | 10 |
| CARLTHORP SCHOOL | Santa Monica | B24Z Education | $21.2M | 7 |
| CREATIVE VISIONS FOUNDATION | Malibu | A40 Arts, Culture & Humanities | $21.2M | 2 |
| GARY AND MARY WEST HEALTH INSTITUTE | La Jolla | H92 Medical Research | $21.2M | 10 |
| NationalAssociationof Music Merchants | Carlsbad | — | $21.2M | 7 |
| CHICANO FEDERATION | San Diego | P81Z Human Services | $21.2M | 2 |
| CALIFORNIA COMMUNICATIONS ACCESS | Concord | P80 Human Services | $21.2M | 11 |
| THE BOYS AND GIRLS CLUBS OF KERN COUNTY | Bakersfield | O210 Youth Development | $21.2M | 2 |
| SHASTA COUNTY HEAD START CHILD | Redding | B22Z Education | $21.2M | 3 |
| DAN MURPHY FOUNDATION | Los Angeles | — | $21.2M | 1 |
| FILM INDEPENDENT | Los Angeles | A310 Arts, Culture & Humanities | $21.1M | 7 |
| DESERT ARC | Palm Desert | — | $21.1M | 3 |
| LULU'S PLACE INC | El Segundo | N30 Recreation & Sports | $21.1M | 0 |