| PARAQUAD INC | St Louis | — | $13.1M | 2 |
| NEW HORIZONS COMMUNITY SUPPORT | Jefferson City | — | $13M | 3 |
| ST LOUIS COUNTRY CLUB | Saint Louis | — | $13M | 7 |
| SECOND HARVEST COMMUNITY FOOD BANK | St Joseph | — | $12.9M | 1 |
| MASONIC HOME OF MISSOURI | Columbia | P750 Human Services | $12.9M | 2 |
| MISSOURI MILITARY ACADEMY | Mexico | B200 Education | $12.9M | 1 |
| COMMUNITY SCHOOL ASSOCIATION | Saint Louis | — | $12.8M | 4 |
| CARPENTERS JOINT TRAINING FUND OF | St Louis | B30 Education | $12.8M | 0 |
| NOVA CENTER OF THE OZARKS INC | Springfield | P80Z Human Services | $12.8M | 1 |
| VNA CORPORATION | Kansas City | E30 Health Care | $12.8M | 8 |
| ELECTRO SAVINGS CREDIT UNION | St Louis | — | $12.7M | 7 |
| MARY QUEEN AND MOTHER ASSOCIATION | St Louis | P750 Human Services | $12.7M | 3 |
| HOPE MONTESSORI ACADEMY | St Louis | B21 Education | $12.7M | 4 |
| West Vue Inc | West Plains | — | $12.7M | 1 |
| Amethyst Place Inc | Kansas City | F22 Mental Health & Crisis Intervention | $12.7M | 1 |
| HEARTLAND CENTER FOR BEHAVIORAL CHANGE | Kansas City | P28Z Human Services | $12.6M | 5 |
| THE OPPORTUNITY TRUST | St Louis | B19 Education | $12.6M | 8 |
| GUADALUPE CENTERS INC | Kansas City | P33Z Human Services | $12.6M | 2 |
| ALEXIAN BROTHERS SHERBROOKE VILLAGE | St Louis | P750 Human Services | $12.5M | 7 |
| STEWARD FAMILY FOUNDATION | St Louis | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $12.5M | 0 |
| AMERICAN ROYAL ASSOCIATION INC | Kansas City | N520 Recreation & Sports | $12.5M | 6 |
| BOOTHEEL COUNSELING SERVICES | Sikeston | F600 Mental Health & Crisis Intervention | $12.4M | 5 |
| PRIVATE EDUCATION EMPLOYERS' TRUST | St Louis | — | $12.4M | 0 |
| DONATE LIFE FOUNDATION | St Louis | E86 Health Care | $12.4M | 13 |
| NORTH CENTRAL MISSOURI MENTAL HEALTH CENTER | Trenton | F32Z Mental Health & Crisis Intervention | $12.3M | 6 |
| CHILDREN'S HOME SOCIETY OF MISSOURI | St Louis | P34Z Human Services | $12.3M | 6 |
| UNITED ASSOCIATION OF PLUMBERS | Kansas City | — | $12.3M | 1 |
| TEAMSTERS LOCAL 682 HEALTH AND WELFARE | Maryland Heights | — | $12.2M | 4 |
| PUBLIC TELEVISION 19 INC | Kansas City | A320 Arts, Culture & Humanities | $12.2M | 5 |
| ST LOUIS REGIONAL PUBLIC MEDIA INC | St Louis | A320 Arts, Culture & Humanities | $12.1M | 8 |
| VISITING NURSE ASSOCIATION OF SOUTHEAST MO | Kennett | E92Z Health Care | $12.1M | 1 |
| TELECOMMUNICATIONS FACILITIES | St Louis | — | $12.1M | 0 |
| DISMAS HOUSE OF ST LOUIS | St Louis | I31 Crime & Legal-Related | $12.1M | 13 |
| VIA CHRISTI VILLAGE MANHATTAN INC | St Louis | — | $12M | 7 |
| ILLINOIS STATE PAINTERS WELFARE FUND | St Louis | — | $12M | 0 |
| The New City School Inc | St Louis | — | $12M | 4 |
| AIDS PROJECT OF THE OZARKS | Springfield | G81Z Diseases, Disorders & Medical Disciplines | $11.9M | 3 |
| QUEEN OF PEACE CENTER | St Louis | F33Z Mental Health & Crisis Intervention | $11.8M | 4 |
| International Brotherhood of Electrical Workers 0124 Local | Kansas City | — | $11.8M | 27 |
| THE SCHOLARSHIP FOUNDATION OF ST LOUIS | St Louis | — | $11.8M | 5 |
| CENTRAL INSTITUTE FOR THE DEAF | Saint Louis | B280 Education | $11.8M | 5 |
| BOOTHEEL AREA INDEPENDENT LIVING | Kennett | P80 Human Services | $11.8M | 8 |
| Linda Hall Library Trusts | Kansas City | — | $11.8M | 4 |
| FOREST HILLS COUNTRY CLUB | Chesterfield | — | $11.8M | 8 |
| Humphreys County Community Health Services Inc | St Louis | E20 Health Care | $11.8M | 12 |
| HARRIS HOUSE FOUNDATION | St Charles | — | $11.8M | 10 |
| Atchison-Holt Electric Cooperative | Rock Port | — | $11.7M | 17 |
| Seton Family of Pediatric Surgeons | St Louis | E30 Health Care | $11.7M | 6 |
| VILLAGE NORTH INC | Saint Louis | P75Z Human Services | $11.6M | 0 |
| MIRIAM FOUNDATION | St Louis | B28Z Education | $11.6M | 5 |
