| DISMAS HOUSE OF ST LOUIS | St Louis | I31 Crime & Legal-Related | $12.1M | 13 |
| BOYS AND GIRLS CLUBS OF SPRINGFIELD INC | Springfield | — | $12M | 3 |
| VIA CHRISTI VILLAGE HAYS INC | St Louis | — | $12M | 9 |
| ILLINOIS STATE PAINTERS WELFARE FUND | St Louis | — | $12M | 0 |
| Gibson Center for Behavioral Change | Cape Girardeau | F22Z Mental Health & Crisis Intervention | $12M | 5 |
| QUEEN OF PEACE CENTER | St Louis | F33Z Mental Health & Crisis Intervention | $11.8M | 4 |
| CENTRAL INSTITUTE FOR THE DEAF | Saint Louis | B280 Education | $11.8M | 5 |
| FOREST HILLS COUNTRY CLUB | Chesterfield | — | $11.8M | 8 |
| HARRIS HOUSE FOUNDATION | St Charles | — | $11.8M | 10 |
| INTERNATIONAL UNION OF OPERATI ENGINEERS LOCAL 101 | Kansas City | — | $11.7M | 20 |
| Atchison-Holt Electric Cooperative | Rock Port | — | $11.7M | 17 |
| EXTENSION FOUNDATION C/O BRYAN CAVE LLP | Kansas City | B054 Education | $11.7M | 0 |
| MISSOURI AND KANSAS LABORERS DISTRICT COUNCIL | Wentzville | — | $11.7M | 17 |
| MISSOURI STATE HIGH SCHOOL ACTIVITIES ASSOCIATION | Columbia | — | $11.6M | 7 |
| The New City School Inc | St Louis | — | $11.6M | 5 |
| COMMUNITY ACTION PARTNERSHIP OF GREATER ST JOSEPH | St Joseph | — | $11.5M | 2 |
| EPWORTH CHILDREN & FAMILY SERVICES INC | St Louis | — | $11.5M | 5 |
| BIOSTL | St Louis | B05 Education | $11.4M | 13 |
| ST LOUIS OFFICE FOR DEVELOPMENTAL DISABILITY RESOURCES | Saint Louis | — | $11.4M | 3 |
| MISSOURI BAPTIST HEALTHCARE FOUNDATION | St Louis | E11 Health Care | $11.3M | 1 |
| Opera Theatre of Saint Louis | St Louis | A6A0 Arts, Culture & Humanities | $11.3M | 7 |
| YOUTHBRIDGE COMMUNITY FOUNDATION | Saint Louis | P70Z Human Services | $11.2M | 1 |
| Magdala House | Saint Louis | F330 Mental Health & Crisis Intervention | $11.2M | 4 |
| ALLEN VILLAGE SCHOOL | Kansas City | B29 Education | $11.2M | 2 |
| MISSOURI TECHNOLOGY CORPORATION | St Louis | — | $11.2M | 1 |
| FULL EMPLOYMENT COUNCIL INC | Kansas City | I20Z Crime & Legal-Related | $11.2M | 3 |
| SAINT THOMAS HEALTH FOUNDATIONS | St Louis | — | $11.2M | 5 |
| PUBLIC SAFETY CREDIT UNION | Kansas City | — | $11.2M | 6 |
| PI BETA PHI FRATERNITY | Town Country | — | $11M | 6 |
| WESTWOOD COUNTRY CLUB | Saint Louis | — | $11M | 6 |
| KANSAS CITY BALLET ASSOCIATION | Kansas City | A630 Arts, Culture & Humanities | $11M | 6 |
| HARRY S TRUMAN CHILDREN'S NEUROLOGICAL CENTER | Independence | P820 Human Services | $11M | 6 |
| MISSOURI LIONS EYE RESEARCH FOUNDATION | Kansas City | G41Z Diseases, Disorders & Medical Disciplines | $11M | 4 |
| COMMUNITY BUILDERS OF KANSAS CITY | Kansas City | L20 Housing & Shelter | $11M | 7 |
| THE COUNTRY CLUB OF ST ALBANS INC | St Albans | — | $11M | 5 |
| THE SCHOLARSHIP FOUNDATION OF ST LOUIS | St Louis | — | $11M | 5 |
| THE DANIEL ACADEMY | Kansas City | B20 Education | $11M | 3 |
| MANOR GROVE INC | St Louis | E910 Health Care | $10.9M | 7 |
| REGIONAL EMERGENCY MEDICAL SERVICES AUTH | St Joseph | E62 Health Care | $10.9M | 6 |
| JEWISH VOCATIONAL SERVICE BUREAU OF KANSAS CITY | Kansas City | — | $10.9M | 2 |
| SOUTHEAST MISSOURI TRANSPORTATION SERVICES INC | Fredericktown | W40Z Public & Societal Benefit | $10.9M | 3 |
| ASCENSION EASTWOOD BEHAVIORAL HEALTH | St Louis | F32Z Mental Health & Crisis Intervention | $10.9M | 16 |
| THE MAGIC HOUSE | St Louis | A520 Arts, Culture & Humanities | $10.8M | 5 |
| THE GENOME PARTNERSHIP | St Louis | S41 Community Improvement & Capacity Building | $10.8M | 1 |
| UNIVERSITY OF CENTRAL MISSOURI FOUNDATION | Warrensburg | B110 Education | $10.8M | 3 |
| Advanced Urologic Associates Inc | Kansas City | E21 Health Care | $10.7M | 4 |
| Community Services League of Jackson County | Independence | P600 Human Services | $10.7M | 4 |
| THE CARRIAGE CLUB INC | Kansas City | — | $10.7M | 8 |
| FORSYTH SCHOOL INC | Saint Louis | B21Z Education | $10.7M | 5 |
| SUNSET COUNTRY CLUB | St Louis | — | $10.6M | 5 |
