| BLUE RIDGE COMMUNITY ACTION INC | Morganton | P20Z Human Services | $11.5M | 4 |
| CHARLOTTE LAB SCHOOL INC | Charlotte | B20 Education | $11.5M | 2 |
| BOYS & GIRLS HOMES OF NC INC | Lake Waccamaw | P700 Human Services | $11.5M | 0 |
| Safe Alliance Inc | Charlotte | P40Z Human Services | $11.4M | 2 |
| Child Nutrition Program Inc | Charlotte | K40Z Food, Agriculture & Nutrition | $11.4M | 1 |
| Vance Charter School Inc | Henderson | B29 Education | $11.4M | 0 |
| GLOBAL SERVICE NETWORK INC | Apex | B99 Education | $11.4M | 2 |
| Swim Across America Inc | Charlotte | T30J Philanthropy, Voluntarism & Grantmaking Foundations | $11.4M | 5 |
| THE BALLOUN FAMILY FOUNDATION | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $11.3M | 0 |
| HOSPICE OF DAVIDSON COUNTY NORTH CAROLINA INC | Lexington | — | $11.3M | 10 |
| URBAN SUSTAINABILITY DIRECTORS NETWORK | Sanford | C35 Environment | $11.3M | 9 |
| GARNER VOLUNTEER FIRE-RESCUE INC | Garner | — | $11.3M | 2 |
| NASH EDGECOMBE WILSON COMMUNITY ACTION INC | Rocky Mount | — | $11.3M | 2 |
| THE TRUST FOR TOMORROW | Fairfield | C32 Environment | $11.3M | 1 |
| CHAPEL HILL COUNTRY CLUB INC | Chapel Hill | N51Z Recreation & Sports | $11.2M | 7 |
| COMMUNITY FOUNDATION OF BURKE COUNTY | Morganton | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $11.2M | 3 |
| HEALTHY START EDUCATION INC | Durham | B20 Education | $11.2M | 2 |
| INTERNATIONAL SOCIETY ON THROMBOSIS AND HAEMOSTASIS INC | Charlotte | — | $11.2M | 10 |
| THE MONTESSORI SCHOOL OF RALEIGH INC | Raleigh | B21Z Education | $11.2M | 3 |
| CHARLOTTE SOCCER ACADEMY | Pineville | N64Z Recreation & Sports | $11.1M | 6 |
| WAYNE COUNTY DEVELOPMENT ALLIANCE INC | Goldsboro | S30 Community Improvement & Capacity Building | $11.1M | 0 |
| RALPH SCOTT LIFESERVICES INC | Burlington | P700 Human Services | $11.1M | 1 |
| SMART START OF FORSYTH COUNTY | Winston Salem | B210 Education | $11.1M | 2 |
| INTRAHEALTH INTERNATIONAL INC | Chapel Hill | E112 Health Care | $11.1M | 0 |
| Sigma Gamma Rho Sorority Inc | Raleigh | — | $11.1M | 0 |
| HARRELLS CHRISTIAN ACADEMY | Harrells | B200 Education | $11.1M | 1 |
| Wade Hampton Golf Club Inc | Cashiers | N50 Recreation & Sports | $11M | 6 |
| Highlands Country Club Inc | Highlands | — | $11M | 7 |
| Northwest NC Community Foundation | Winstonsalem | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $11M | 1 |
| The Ed Fitts Charitable Foundation | Littleton | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $11M | 0 |
| ALLIANCE CENTER FOR EDUCATION INC | Charlotte | B20 Education | $11M | 2 |
| HOSPICE OF ROCKINGHAM COUNTY INC | Wentworth | — | $11M | 5 |
| CAROLINA BALLET INC | Raleigh | A630 Arts, Culture & Humanities | $10.9M | 3 |
| SANDHILLS INDEPENDENT SCHOOL CORPORATION | Southern Pines | B250 Education | $10.9M | 5 |
| HealthAccess Inc | Greenville | — | $10.9M | 9 |
| CHOANOKE AREA DEVELOPMENT ASSOCIATION OF NORTH CAROLINA INC | Rich Square | L21Z Housing & Shelter | $10.9M | 1 |
| Sandra and Leon Levine Jewish Community Center Inc | Charlotte | N20Z Recreation & Sports | $10.9M | 7 |
| THE NATIONAL BOARD OF EXAMINERS IN OPTOMETRY INC | Charlotte | P20Z Human Services | $10.9M | 13 |
| THE BOLICK FOUNDATION | Conover | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.8M | 1 |
| ROCKY MOUNT PREPARATORY SCHOOL INC | Rocky Mount | B240 Education | $10.8M | 1 |
| FAMILY SERVICE OF THE PIEDMONT INC | Jamestown | P400 Human Services | $10.8M | 4 |
| LSA Pharmacy Inc | Salisbury | — | $10.8M | 8 |
| HOLY ANGELS INC | Belmont | — | $10.7M | 5 |
| North American Transmission Forum Inc | Charlotte | S41 Community Improvement & Capacity Building | $10.7M | 5 |
| Lutheran Home - Albemarle Inc | Salisbury | — | $10.7M | 5 |
| The Franklin School of Innovation Inc | Asheville | B29 Education | $10.7M | 0 |
| Clover Garden School Inc | Burlington | X20 Religion-Related | $10.7M | 0 |
| CAROLINAS FOOTBALL CLUB | Cornelius | N64 Recreation & Sports | $10.7M | 1 |
| MEDICAL REVIEW OF NORTH CAROLINA INC | Raleigh | E020 Health Care | $10.7M | 21 |
| Socrates Academy Inc | Matthews | B29 Education | $10.6M | 3 |
