| NATIONAL INSTITUTE OF MINORITY ECONOMIC | Durham | — | $12.2M | 6 |
| FAMILY SERVICES INC | Winstonsalem | P200 Human Services | $12.2M | 3 |
| Residential Services Inc | Chapel Hill | F33Z Mental Health & Crisis Intervention | $12.1M | 2 |
| GASTON COMMUNITY FOUNDATION | Gastonia | T310 Philanthropy, Voluntarism & Grantmaking Foundations | $12.1M | 1 |
| STACKS OPEN INTERNET FOUNDATION | Cary | — | $12M | 6 |
| THE FLETCHER SCHOOL INC | Charlotte | — | $12M | 5 |
| JAARS INC | Waxhaw | S80 Community Improvement & Capacity Building | $11.9M | 3 |
| Catapult Employers Association Inc | Charlotte | — | $11.9M | 8 |
| SENIOR SERVICES INC | Winstonsalem | P81Z Human Services | $11.8M | 3 |
| Girl Scouts - North Carolina Coastal Pines | Raleigh | O42 Youth Development | $11.7M | 7 |
| Cape Fear Country Club Incorporated | Wilmington | — | $11.7M | 8 |
| FELLOWSHIP HALL INC | Greensboro | F220 Mental Health & Crisis Intervention | $11.7M | 7 |
| FOUNDATION FOR THE CHARLOTTE JEWISH | Charlotte | X123 Religion-Related | $11.7M | 2 |
| COMSERV INC | Lenoir | P73Z Human Services | $11.7M | 4 |
| TRINITY ACADEMY OF RALEIGH | Raleigh | B20 Education | $11.7M | 2 |
| CRYSTAL COAST TOURNAMENT INC | Morehead City | P34J Human Services | $11.7M | 1 |
| URBAN MINISTRIES OF WAKE COUNTY | Raleigh | P600 Human Services | $11.7M | 5 |
| UNION COUNTY CHARTER EDUCATION | Indian Trail | B24 Education | $11.7M | 0 |
| WESTERN CAROLINA UNIVERSITY | Cullowhee | B43I Education | $11.7M | 0 |
| THE INDUSTRIAL COMMONS | Morganton | S31 Community Improvement & Capacity Building | $11.7M | 4 |
| COMMUNITY REAL PROPERTY HOLDINGS INC | Charlotte | P117 Human Services | $11.6M | 5 |
| CHARLOTTE BALLET | Charlotte | A620 Arts, Culture & Humanities | $11.6M | 5 |
| Lutheran Retirement Center - Salisbury Inc | Salisbury | L22Z Housing & Shelter | $11.6M | 6 |
| SOCIETY FOR THE PREVENTION OF | Raleigh | D200 Animal-Related | $11.6M | 1 |
| COMPASSION HEALTH CARE INC | Yanceyville | E32Z Health Care | $11.6M | 11 |
| PISGAH LEGAL SERVICES | Asheville | I80Z Crime & Legal-Related | $11.6M | 5 |
| THE FOUNDATION OF FIRSTHEALTH INC | Pinehurst | — | $11.6M | 4 |
| NC STATE UNIVERSITY PARTNERSHIP CORP | Raleigh | — | $11.5M | 5 |
| DAY ONE RELIEF | Chapel Hill | M20 Public Safety, Disaster Preparedness & Relief | $11.5M | 0 |
| BLUE RIDGE COMMUNITY ACTION INC | Morganton | P20Z Human Services | $11.5M | 4 |
| THE UNIVERSITY OF NORTH CAROLINA AT | Greensboro | B110 Education | $11.5M | 2 |
| CHILDREN'S HOPE ALLIANCE FOUNDATION | Barium Springs | P73 Human Services | $11.4M | 2 |
| Child Nutrition Program Inc | Charlotte | K40Z Food, Agriculture & Nutrition | $11.4M | 1 |
| Vance Charter School Inc | Henderson | B29 Education | $11.4M | 0 |
| Swim Across America Inc | Charlotte | T30J Philanthropy, Voluntarism & Grantmaking Foundations | $11.4M | 5 |
| CHARLOTTE LAB SCHOOLS INC | Charlotte | B20 Education | $11.3M | 2 |
| BOYS & GIRLS HOMES OF NC INC | Lake Waccamaw | P700 Human Services | $11.3M | 0 |
| THE BALLOUN FAMILY FOUNDATION | Wilmington | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $11.3M | 0 |
| URBAN SUSTAINABILITY DIRECTORS NETWORK | Sanford | C35 Environment | $11.3M | 9 |
| SOUTHERN VISION ALLIANCE | Durham | W99 Public & Societal Benefit | $11.3M | 7 |
| GARNER VOLUNTEER FIRE-RESCUE INC | Garner | — | $11.3M | 2 |
| NASH EDGECOMBE WILSON COMMUNITY ACTION | Rocky Mount | — | $11.3M | 2 |
| HABITAT FOR HUMANITY | Chapel Hill | — | $11.3M | 2 |
| THE TRUST FOR TOMORROW | Fairfield | C32 Environment | $11.3M | 1 |
| WESTCHESTER COUNTRY DAY SCHOOL INC | High Point | B24Z Education | $11.2M | 2 |
| COMMUNITY FOUNDATION OF BURKE COUNTY | Morganton | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $11.2M | 3 |
| FREEDOM HOUSE RECOVERY CENTER INC | Chapel Hill | — | $11.2M | 4 |
| WAKE CHRISTIAN ACADEMY INC | Raleigh | B24Z Education | $11.2M | 1 |
| Conserving Carolina | Hendersonville | C340 Environment | $11.2M | 2 |
| INTERNATIONAL SOCIETY ON THROMBOSIS | Charlotte | — | $11.2M | 10 |
