| CROWLEY COUNTY NURSING CENTER INC | Ordway | E90 Health Care | $4.7M | 0 |
| FIRST DESCENTS | Denver | N20 Recreation & Sports | $4.7M | 5 |
| ROCKY MOUNTAIN CHILDREN'S HEALTH | Arvada | P60 Human Services | $4.7M | 2 |
| The Odyssey School | Denver | B24 Education | $4.7M | 1 |
| DENVER ACADEMY OF TORAH | Denver | B20Z Education | $4.7M | 1 |
| COLORADO COMMUNITY HEALTH | Denver | E39Z Health Care | $4.7M | 8 |
| HIGH COUNTRY NEWS | Paonia | C600 Environment | $4.7M | 2 |
| HOMEWARD ALLIANCE INC | Fort Collins | P80 Human Services | $4.7M | 1 |
| ALPHA PHI INTERNATIONAL FRATERNITY- | Denver | — | $4.7M | 0 |
| GILL FOUNDATION | Denver | — | $4.6M | 3 |
| MONARCH MONTESSORI | Denver | B29 Education | $4.6M | 1 |
| FOUNDATION FOR EDUCATIONAL EXCELLENCE | Denver | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $4.6M | 1 |
| CASTLE ROCK COMMUNITY INTER CHURCH | Castle Rock | P60Z Human Services | $4.6M | 1 |
| HOPE COMMUNITIES INC | Denver | L210 Housing & Shelter | $4.6M | 1 |
| JOINT INITIATIVES FOR YOUTH AND FAMILIES | Colorado Springs | Z99 Unknown | $4.6M | 2 |
| Peoples Credit Union | Springfield | — | $4.6M | 1 |
| Compass Academy | Denver | B25 Education | $4.6M | 2 |
| Colorado Succeeds | Denver | B05 Education | $4.6M | 5 |
| BUILD CHANGE | Denver | U40 Science & Technology | $4.6M | 8 |
| ALPHA PHI INTERNATIONAL FRATERNITY- | Denver | — | $4.6M | 0 |
| FLORA AND MORRIS MIZEL FOUNDATION I | Denver | T20Z Philanthropy, Voluntarism & Grantmaking Foundations | $4.6M | 0 |
| COMMONSPIRIT HEALTH FOUNDATION | Englewood | X22 Religion-Related | $4.6M | 5 |
| RICARDO FLORES MAGON ACADEMYINCORPORATED | Denver | — | $4.6M | 1 |
| VINDEKET | Fort Collins | K30 Food, Agriculture & Nutrition | $4.5M | 1 |
| WELD COMMUNITY FOUNDATION | Greeley | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $4.5M | 1 |
| PARACLETE MISSION GROUP INC | Colorado Springs | X02 Religion-Related | $4.5M | 1 |
| TELLURIDE COUNCIL FOR THE ARTS AND HUMANITIES | Telluride | — | $4.5M | 1 |
| ROCKY MOUNTAIN BIOLOGICAL LABORATORY | Crested Butte | U50Z Science & Technology | $4.5M | 5 |
| JEROME V BRUNI FOUNDATION | Colorado Springs | — | $4.5M | 0 |
| COMPETENCY & CREDENTIALING INSTITUTE | Littleton | — | $4.5M | 5 |
| GLOBAL SERVICE OFFICE | Lafayette | — | $4.5M | 2 |
| CONTINUING LEGAL EDUCATION IN | Denver | B53Z Education | $4.5M | 4 |
| WALKING MOUNTAINS | Avon | B99 Education | $4.5M | 4 |
| MOVEMENT ADVANCEMENT PROJECT | Boulder | R26 Civil Rights, Social Action & Advocacy | $4.5M | 6 |
| MOUNTAIN STATES LEGAL FOUNDATION | Lakewood | R600 Civil Rights, Social Action & Advocacy | $4.5M | 7 |
| HUMANITIX USA LIMITED | Denver | P20 Human Services | $4.5M | 2 |
| Bibles For The World | Colorado Springs | X21Z Religion-Related | $4.5M | 2 |
| THE LEARNING SOURCE | Denver | B61Z Education | $4.5M | 2 |
| Wyatt Academy | Denver | B20 Education | $4.5M | 1 |
| REGION SIX ALCOHOL & DRUG ABUSE | Las Animas | F22Z Mental Health & Crisis Intervention | $4.5M | 0 |
| Academy for Advanced and Creative | Colorado Springs | B29 Education | $4.5M | 1 |
| COMMUNITY HOUSING DEVELOPMENT | Greenwood Village | L21 Housing & Shelter | $4.4M | 1 |
| DENVER URBAN GARDENS | Denver | C500 Environment | $4.4M | 1 |
| MAJOR LEAGUE BASEBALL PLAYERS | Colorado Springs | — | $4.4M | 8 |
| COMMUNITY SERVICES OF BROOMFIELD | Broomfield | P60 Human Services | $4.4M | 1 |
| ZEFF KESHER FOUNDATION | Denver | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $4.4M | 0 |
| JUDI'S HOUSE INC | Aurora | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $4.4M | 4 |
| Merit Academy | Woodland Park | B20 Education | $4.4M | 1 |
| Moonshot edVentures | Denver | B90 Education | $4.4M | 3 |
| LION GLOBAL FOUNDATION | Denver | A50 Arts, Culture & Humanities | $4.4M | 1 |
