| GAY LESBIAN BISEXUAL & TRANSGEND COMMUNITY CENTER OF COLORADO | Denver | — | $4.1M | 2 |
| ICLEI - LOCAL GOVERNMENTS FOR SUSTAINABILITY USA INC | Denver | C010 Environment | $4.1M | 2 |
| BLUE PEAKS DEVELOPMENTAL SERVICES INC | Alamosa | P700 Human Services | $4M | 2 |
| THE CHANDA PLAN FOUNDATION | Lakewood | — | $4M | 13 |
| MANNA - THE DURANGO SOUP KITCHEN | Durango | — | $4M | 3 |
| LAS ANIMAS COUNTY REHABILITATION CENTER | Trinidad | P82 Human Services | $4M | 2 |
| ASPEN CENTER FOR PHYSICS | Aspen | U35Z Science & Technology | $4M | 1 |
| Columbine-Lakewood Colorado Soccer Association | Denver | N70 Recreation & Sports | $4M | 1 |
| STRINGS MUSIC FESTIVAL | Steamboat Springs | A680 Arts, Culture & Humanities | $4M | 1 |
| Columbine Community Foundation | Winter Park | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $4M | 1 |
| GUNNISON VALLEY HEALTH FOUNDATION | Gunnison | E60 Health Care | $4M | 5 |
| TINY TIM CENTER INC DBA TLC LEARNING CENTER | Longmont | B21Z Education | $4M | 0 |
| MERCY HOUSING WHEATON NFP | Denver | L21 Housing & Shelter | $4M | 4 |
| COLORADO WOMEN'S EMPLOYMENT & EDUCATION INC | Denver | J200 Employment | $4M | 5 |
| Mountain States Children's Home | Longmont | P70Z Human Services | $4M | 2 |
| ACTIVATE WORK INC | Denver | P20 Human Services | $4M | 2 |
| NEW BEGINNING RECOVERY CENTER INC | Littleton | E50 Health Care | $4M | 0 |
| COLLABORATIVE HEALING INITIATIVE WITHIN COMMUNITIES INC | Denver | P50 Human Services | $4M | 3 |
| REVISION | Denver | C60 Environment | $4M | 1 |
| Thistle Community Housing | Boulder | L210 Housing & Shelter | $4M | 2 |
| Crown Pointe Academy Building Corporation | Westminster | B02 Education | $4M | 1 |
| MESA YOUTH SERVICES INC | Grand Junction | P300 Human Services | $4M | 1 |
| DanceSafe Inc | Lakewood | F20 Mental Health & Crisis Intervention | $4M | 3 |
| The Bold Foundation Inc | Denver | B12 Education | $4M | 0 |
| NATIONAL BOARD OF SURGICAL TECHNOLOGY AND SURGICAL ASSISTING | Littleton | — | $4M | 3 |
| Committee For Catholic Secondary Educati | Colorado Springs | B25Z Education | $4M | 3 |
| CARY BROWN FAMILY FOUNDATION | Colorado Springs | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $4M | 2 |
| DOWNTOWN DENVER PARTNERSHIP INC | Denver | — | $3.9M | 7 |
| COMMON SENSE INSTITUTE | Greenwood Village | V05 Social Science | $3.9M | 6 |
| GRAND VALLEY IRRIGATION COMPANY | Grand Junction | — | $3.9M | 9 |
| THE LONGMONT COMMUNITY FOUNDATION | Longmont | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $3.9M | 1 |
| TRIBE RECOVERY HOMES INC | Denver | F50 Mental Health & Crisis Intervention | $3.9M | 10 |
| BLIND INSTITUTE OF TECHNOLOGY | Thornton | Z99 Unknown | $3.9M | 2 |
| METROPOLITAN DENVER HOMELESS INITIATIVE INC | Denver | L80 Housing & Shelter | $3.9M | 2 |
| Colorado Rural Electric Association | Denver | — | $3.9M | 7 |
| Denver Gold Group Inc | Denver | — | $3.9M | 9 |
| PUEBLO COUNTRY CLUB | Pueblo | — | $3.9M | 1 |
| THE CHARLOU FOUNDATION | Cherry Hills Village | A11 Arts, Culture & Humanities | $3.9M | 0 |
| COLORADO INSURANCE GUARANTY ASSN | Denver | — | $3.9M | 0 |
| Colorado Oil & Gas Association | Denver | — | $3.9M | 3 |
| GLOBALADVANTAGE | Pueblo West | B80 Education | $3.9M | 0 |
| THE STRANDBERG FAMILY FOUNDATION C/O JEFFREY C KIRWOOD | Avon | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $3.9M | 0 |
| HERS-HIGHER EDUCATION RESOURCE SERVICES | Denver | B02 Education | $3.9M | 2 |
| CARING FOR COLORADO FOUNDATION | Denver | E12 Health Care | $3.9M | 6 |
| PERRY PARK COUNTRY CLUB | Larkspur | — | $3.9M | 0 |
| COALITION FOR THE UPPER SOUTH PLATTE | Lake George | C013 Environment | $3.9M | 0 |
| RESTORATION CHRISTIAN MINISTRIES | Aurora | P20 Human Services | $3.9M | 1 |
| RECOVERY RESOURCES | Snowmass | E50 Health Care | $3.8M | 1 |
| BOULDER FOOD RESCUE | Boulder | K31 Food, Agriculture & Nutrition | $3.8M | 2 |
| BIXBY & ASSOCIATES | Boulder | Z99Z Unknown | $3.8M | 1 |
