| The Center for Relationship Educati | Greenwood Village | E40 Health Care | $4.1M | 2 |
| ASSISI HOMES - COLONY PARK INC | Denver | — | $4.1M | 7 |
| Montbello Organizing Committee | Denver | B19 Education | $4.1M | 2 |
| TCA BUILDING CORPORATION | Colorado Springs | P11 Human Services | $4.1M | 0 |
| SPRING INSTITUTE FOR | Denver | — | $4.1M | 1 |
| COMPASS MONTESSORI SCHOOL | Wheat Ridge | B20Z Education | $4.1M | 0 |
| WIDE HORIZON INC | Wheat Ridge | E91Z Health Care | $4.1M | 1 |
| DURANGO 4-C COUNCIL INC | Durango | B22Z Education | $4.1M | 0 |
| LEPTAS FOUNDATION TRUST | Denver | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $4.1M | 0 |
| GROWING HOME INC | Westminster | X20 Religion-Related | $4.1M | 2 |
| COLORADO UPLIFT INC | Denver | B900 Education | $4.1M | 2 |
| BLUFF LAKE NATURE CENTER | Denver | C600 Environment | $4.1M | 1 |
| COLORADO SOCIETY OF CPA'S | Englewood | — | $4.1M | 3 |
| MERCY HOUSING SOUTHWEST | Denver | L19 Housing & Shelter | $4.1M | 9 |
| Bethesda Associates | Colorado Springs | X120 Religion-Related | $4.1M | 11 |
| GAY LESBIAN BISEXUAL & TRANSGEND | Denver | — | $4.1M | 2 |
| OUR HOUSE INC | Colorado Springs | P80 Human Services | $4.1M | 2 |
| BLUE PEAKS DEVELOPMENTAL SERVICES INC | Alamosa | P700 Human Services | $4M | 2 |
| USA Shooting Inc | Colorado Springs | Z99 Unknown | $4M | 3 |
| THE CHANDA PLAN FOUNDATION | Lakewood | — | $4M | 13 |
| MANNA - THE DURANGO SOUP KITCHEN | Durango | — | $4M | 3 |
| ASPEN CENTER FOR PHYSICS | Aspen | U35Z Science & Technology | $4M | 1 |
| PIKES PEAK OR BUST RODEO FOUNDATION | Colorado Springs | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $4M | 1 |
| STRINGS MUSIC FESTIVAL | Steamboat Springs | A680 Arts, Culture & Humanities | $4M | 1 |
| GUNNISON VALLEY HEALTH FOUNDATION | Gunnison | E60 Health Care | $4M | 5 |
| TINY TIM CENTER INC | Longmont | B21Z Education | $4M | 0 |
| LUTHERAN MEDICAL CENTER FOUNDATION | Wheat Ridge | E11 Health Care | $4M | 4 |
| COLORADO WOMEN'S EMPLOYMENT & EDUCATION | Denver | J200 Employment | $4M | 5 |
| Mountain States Children's Home | Longmont | P70Z Human Services | $4M | 2 |
| ACTIVATE WORK INC | Denver | P20 Human Services | $4M | 2 |
| NEW BEGINNING RECOVERY CENTER INC | Littleton | E50 Health Care | $4M | 0 |
| PADDINGTON STATION INC | Denver | B21 Education | $4M | 2 |
| BIXBY & ASSOCIATES | Boulder | Z99Z Unknown | $4M | 1 |
| COLLABORATIVE HEALING INITIATIVE | Denver | P50 Human Services | $4M | 3 |
| REVISION | Denver | C60 Environment | $4M | 1 |
| Thistle Community Housing | Boulder | L210 Housing & Shelter | $4M | 2 |
| MESA YOUTH SERVICES INC | Grand Junction | P300 Human Services | $4M | 1 |
| EARLY CHILDHOOD COUNCIL OF THE SAN LUIS | Alamosa | P02 Human Services | $4M | 3 |
| NATIONAL BOARD OF SURGICAL TECHNOLOGY | Littleton | — | $4M | 3 |
| Committee For Catholic Secondary Educati | Colorado Springs | B25Z Education | $4M | 3 |
| DOWNTOWN DENVER PARTNERSHIP INC | Denver | — | $3.9M | 7 |
| COMMON SENSE INSTITUTE | Greenwood Village | V05 Social Science | $3.9M | 6 |
| GRAND VALLEY IRRIGATION COMPANY | Grand Junction | — | $3.9M | 9 |
| CENTER FOR POLICY RESEARCH | Denver | W00F Public & Societal Benefit | $3.9M | 4 |
| USA Swimming Foundation Inc | Colorado Springs | N11 Recreation & Sports | $3.9M | 4 |
| TRIBE RECOVERY HOMES INC | Denver | F50 Mental Health & Crisis Intervention | $3.9M | 10 |
| BLIND INSTITUTE OF TECHNOLOGY | Thornton | Z99 Unknown | $3.9M | 2 |
| Colorado Rural Electric Association | Denver | — | $3.9M | 7 |
| Denver Gold Group Inc | Denver | — | $3.9M | 9 |
| PUEBLO COUNTRY CLUB | Pueblo | — | $3.9M | 1 |
