| BEHAVIORAL HEALTHCARE SERVICES INC | Owensboro | P80 Human Services | $13.4M | 3 |
| MADONNA MANOR INC | Villa Hills | E910 Health Care | $13.3M | 7 |
| LG&E Energy Corp VEBA | Louisville | — | $13.2M | 1 |
| CONTINUING CARE HOSPITAL INC | Lexington | — | $13.1M | 12 |
| INTERNATIONAL COACH FEDERATION INC | Lexington | — | $13M | 0 |
| SPECIALIZED ALTERNATIVES FOR | Lexington | P32 Human Services | $13M | 6 |
| LOUISVILLE ZOO FOUNDATION INC | Louisville | D115 Animal-Related | $13M | 0 |
| Children's Home of Northern Kentucky Inc | Covington | P730 Human Services | $13M | 6 |
| Disabled American Veterans National Service Foundation | Erlanger | — | $12.8M | 0 |
| Christian Academy of Indiana Inc | Louisville | B20 Education | $12.8M | 6 |
| TJ REGIONAL HEALTH INC | Glasgow | E192 Health Care | $12.8M | 10 |
| TRINITY HIGH SCHOOL FOUNDATION | Louisville | — | $12.8M | 0 |
| Kentucky Chamber of Commerce Inc | Frankfort | — | $12.4M | 10 |
| THE HEALING PLACE INC | Louisville | — | $12.4M | 3 |
| NATIONAL CENTER FOR FAMILIES LEARNING | Louisville | B92Z Education | $12.3M | 5 |
| COMMUNICARE SERVICES INC | Elizabethtown | E11 Health Care | $12.3M | 9 |
| JEWISH HERITAGE FUND FOR EXCELLENCE INC | Louisville | E19 Health Care | $12.2M | 2 |
| Simmons College of Kentucky Inc | Louisville | B43 Education | $12.1M | 4 |
| KENTUCKY INSURANCE GUARANTY ASSOCIATION | Louisville | — | $12.1M | 2 |
| IMPACT ENERGY INDUSTRY HEALTH TRUST | Lexington | J40 Employment | $12.1M | 1 |
| HARBOR HOUSE OF LOUISVILLE INC | Louisville | R99Z Civil Rights, Social Action & Advocacy | $12.1M | 2 |
| JAMES GRAHAM BROWN FOUNDATION INC | Louisville | — | $11.9M | 13 |
| FOUNDATION FOR APPALACHIAN KENTUCKY INC | Hazard | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $11.8M | 1 |
| WESLEY MANOR RETIREMENT COMMUNITY INC | Louisville | L22 Housing & Shelter | $11.7M | 4 |
| Autotruck Financial Credit Union | Louisville | — | $11.7M | 3 |
| CAVE HILL CEMETERY COMPANY | Louisville | — | $11.6M | 5 |
| ACUMEN COUNSELING SERVICES INC | Owensboro | F60 Mental Health & Crisis Intervention | $11.6M | 6 |
| THE GREATER LOUISVILLE WORKFORCE | Louisville | S31 Community Improvement & Capacity Building | $11.5M | 1 |
| KENTUCKY CATTLEMEN'S FOUNDATION INC | Lexington | B82Z Education | $11.4M | 0 |
| CLEAN STREAMS FOUNDATION INC | Lexington | C122 Environment | $11.4M | 0 |
| NORTH FORK VALLEY COMMUNITY | Hazard | — | $11.4M | 0 |
| GENERAL DRIVERS WAREHOUSEMEN AND | Louisville | — | $11.3M | 12 |
| CARMEL MANOR INC | Fort Thomas | E910 Health Care | $11.3M | 4 |
| REACHING AND TEACHING INTERNATIONAL | Louisville | X21 Religion-Related | $11.3M | 1 |
| UNLAWFUL NARCOTICS INVESTIGATIONS | Somerset | F22 Mental Health & Crisis Intervention | $11.1M | 0 |
| COMMONWEALTH FUND FOR KET INC | Lexington | A112 Arts, Culture & Humanities | $11M | 2 |
| CATHOLIC EDUCATION FOUNDATION INC | Louisville | B82Z Education | $11M | 4 |
| KENTUCKY HUMANE SOCIETY - ANIMAL RESCUE | Louisville | D200 Animal-Related | $10.9M | 5 |
| ASHLAND NURSING HOME CORP | Ashland | E91 Health Care | $10.9M | 8 |
| Redwood School & Rehabilitation Inc | Ft Mitchell | E500 Health Care | $10.9M | 7 |
| EASTERN KENTUCKY UNIVERSITY FOUNDATION | Richmond | B110 Education | $10.8M | 3 |
| HOSPICE OF LAKE CUMBERLAND INC | Somerset | P74Z Human Services | $10.8M | 6 |
| LOUISVILLE & JEFFERSON COUNTY | Louisville | I80Z Crime & Legal-Related | $10.7M | 1 |
| PRESBYTERIAN HOMES AND SERVICES | Louisville | P75Z Human Services | $10.7M | 2 |
| BOURBON HEIGHTS INC | Paris | E91Z Health Care | $10.6M | 1 |
| COMPREHEND INC | Maysville | F33Z Mental Health & Crisis Intervention | $10.5M | 2 |
| Sandy Valley Transportation Services Inc | Prestonsburg | — | $10.4M | 0 |
| INTERNATIONAL UNION OF OPERATING ENG LOCAL 181 | Henderson | — | $10.4M | 13 |
| INDIGO FOUNDATION | Louisville | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $10.4M | 1 |
| KENTUCKY NONPROFIT NETWORK INC GROUP | Lexington | Y43 Mutual & Membership Benefit | $10.4M | 2 |
