| INSTITUTE CAPITAL INC | Durham | S30 Community Improvement & Capacity Building | $6.2M | 3 |
| Mt Olive Family Medicine Center Inc | Mount Olive | E20Z Health Care | $6.2M | 7 |
| DURHAM NATIVITY SCHOOL INC | Durham | B24 Education | $6.2M | 1 |
| ATHLETIC FOUNDATION OF THE UNIVERSITY | Charlotte | B114 Education | $6.2M | 3 |
| Kerry & Simone Vickar Family Foundation | Charlotte | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $6.2M | 1 |
| BOYD-GLENN FOUNDATION | Montreat | — | $6.2M | 0 |
| STEELE CREEK CHARTER EDUCATION | Charlotte | B24 Education | $6.2M | 0 |
| NORTH HILLS CHRISTIAN SCHOOL | Salisbury | B24Z Education | $6.2M | 1 |
| WEST LAKE EDUCATION FOUNDATION INC | Cornelius | B29 Education | $6.1M | 0 |
| The Independence Fund Inc | Charlotte | W30 Public & Societal Benefit | $6.1M | 5 |
| Charlotte Center for Legal Advocacy Inc | Charlotte | I80Z Crime & Legal-Related | $6.1M | 6 |
| MACON CITIZENS HABILITIES INC | Franklin | — | $6.1M | 2 |
| THE BURLINGTON SCHOOL INC | Burlington | — | $6.1M | 1 |
| GREENSBORO-RANDOLPH MEGASITE FOUNDATION | Greensboro | S30 Community Improvement & Capacity Building | $6.1M | 0 |
| NORTH CAROLINA MUSEUM OF HISTORY | Raleigh | A50 Arts, Culture & Humanities | $6.1M | 1 |
| Northwest NC Community Foundation | Winstonsalem | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $6.1M | 1 |
| High Point Country Club Inc | High Point | N50 Recreation & Sports | $6.1M | 6 |
| SOUTHMOUNTAIN CHILDREN AND FAMILY | Morganton | P70Z Human Services | $6.1M | 4 |
| GUIL-RAND FIRE PROTECTIVE ASSOCIATION | Archdale | M24Z Public Safety, Disaster Preparedness & Relief | $6.1M | 0 |
| AJ FLETCHER FOUNDATION | Raleigh | T11 Philanthropy, Voluntarism & Grantmaking Foundations | $6.1M | 1 |
| PERSON COUNTY GROUP HOMES INC | Roxboro | P73Z Human Services | $6.1M | 1 |
| Community Public Charter School | Stanley | B29 Education | $6.1M | 1 |
| St Luke's Physician Network Inc | Columbus | E32 Health Care | $6.1M | 5 |
| University Health Systems of Eastern | Greenville | E70 Health Care | $6M | 1 |
| The Foundation of Shalom Park | Charlotte | N500 Recreation & Sports | $6M | 0 |
| LSA Elms at Tanglewood Inc | Salisbury | — | $6M | 6 |
| Charmeck Family Justice Center Inc | Charlotte | I71 Crime & Legal-Related | $6M | 0 |
| SPECIAL OLYMPICS NORTH CAROLINA INC | Morrisville | — | $6M | 1 |
| Next Generation Academy | Greensboro | B24 Education | $6M | 0 |
| United Faith Christian Academy | Charlotte | B20 Education | $6M | 0 |
| THE HUISKING FOUNDATION INC | Raleigh | — | $6M | 0 |
| UNITED HEALTH CENTERS | Winstonsalem | E20 Health Care | $6M | 4 |
| THE ENOLA GROUP | Morganton | — | $6M | 1 |
| CENTER FOR HEALTHY LIVING INC | Charlotte | P70 Human Services | $6M | 1 |
| Youngsville Academy Charter School Inc | Youngsville | B24 Education | $6M | 0 |
| SCHOOL OF GOVERNMENT SERVICES | Chapel Hill | B90 Education | $6M | 10 |
| FERN LEAF COMMUNITY CHARTER SCHOOL | Fletcher | B24 Education | $5.9M | 1 |
| PLANNED PARENTHOOD VOTES SOUTH ATLANTIC | Raleigh | R61 Civil Rights, Social Action & Advocacy | $5.9M | 3 |
| SNOWBIRD OUTFITTERS INC | Andrews | O55 Youth Development | $5.9M | 3 |
| Heineman-Robicsek Foundation Inc | Charlotte | — | $5.9M | 1 |
| MECKLENBURG AQUATIC CLUB | Charlotte | — | $5.9M | 2 |
| NATIONAL HUMANITIES CENTER | Research Triangle Park | A70 Arts, Culture & Humanities | $5.9M | 5 |
| The New Dimensions School Inc | Morganton | B29 Education | $5.9M | 3 |
| The North Carolina Arboretum Society | Asheville | C410 Environment | $5.9M | 0 |
| EAST LINCOLN FIRE DEPARTMENT STATION #3 | Stanley | M24 Public Safety, Disaster Preparedness & Relief | $5.9M | 2 |
| CALDWELL HOSPICE AND PALLIATIVE | Lenoir | P74Z Human Services | $5.8M | 0 |
| Rosedale Health and Wellness Pc | Huntersville | — | $5.8M | 1 |
| BERRY CHARITABLE FOUNDATION | Greensboro | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $5.8M | 0 |
| Institute for the Development of Young Leaders | Durham | Y99 Mutual & Membership Benefit | $5.8M | 0 |
| JOHN WILLIAM POPE FOUNDATION | Raleigh | — | $5.8M | 5 |
