| THE JOSEPH AND ROBERT CORNELL | Charlottesville | — | $10.4M | 2 |
| HOSPITAL FOR EXTENDED RECOVERY | Norfolk | E20 Health Care | $10.4M | 7 |
| ZERO PROSTATE CANCER | Alexandria | E99 Health Care | $10.4M | 11 |
| ATLANTIC SHORES CHRISTIAN SCHOOLS | Chesapeake | B20P Education | $10.3M | 2 |
| NATIONAL ASSOCIATION OF INSURANCE AND | Arlington | — | $10.3M | 11 |
| VIRGINIA ORGANIZING INC | Charlottesville | S21Z Community Improvement & Capacity Building | $10.3M | 2 |
| The Maintenance of Way Employees | Arlington | — | $10.3M | 2 |
| VIRGINIA COMMONWEALTH UNIVERSITY REAL | Richmond | B43 Education | $10.2M | 1 |
| NatureServe | Arlington | C030 Environment | $10.2M | 10 |
| AMERICAN PRESS INSTITUTE INC | Arlington | A03 Arts, Culture & Humanities | $10.2M | 8 |
| YWCA RICHMOND | Richmond | P27Z Human Services | $10.2M | 3 |
| TOUCHSTONE ENERGY COOPERATIVE INC | Arlington | S41 Community Improvement & Capacity Building | $10.2M | 0 |
| GOPAC EDUCATION FUND INC | Arlington | — | $10.2M | 1 |
| HEREDITARY ANGIOEDEMA ASSOCIATION INC | Fairfax | E99 Health Care | $10.2M | 6 |
| LOUDOUN COUNTRY DAY SCHOOL INC | Leesburg | B24Z Education | $10.1M | 6 |
| Team C Charitable Foundation | Virginia Beach | — | $10.1M | 0 |
| THE SOURCE FOR LEARNING INC | Reston | A32Z Arts, Culture & Humanities | $10.1M | 6 |
| COMMONWEALTH FOUNDATIONS | Richmond | T21 Philanthropy, Voluntarism & Grantmaking Foundations | $10.1M | 0 |
| AMERICAN STATISTICAL ASSOCIATION | Alexandria | — | $10.1M | 7 |
| American Jobs and Growth Fund | Vienna | — | $10M | 0 |
| Free Clinic of the New River Valley Inc | Christiansburg | — | $10M | 8 |
| ARDLEIGH IMPACT CORP | Springfield | — | $10M | 0 |
| SILVER VALLEY RESEARCH FOUNDATION | McLean | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $10M | 0 |
| MOUNT VERNON COUNTRY CLUB INC | Alexandria | — | $9.9M | 6 |
| THE JAMES W AND FRANCES GIBSON | Bristol | T90 Philanthropy, Voluntarism & Grantmaking Foundations | $9.9M | 2 |
| SOUTHEAST RURAL COMMUNITY ASSISTANCE | Roanoke | W80Z Public & Societal Benefit | $9.9M | 1 |
| HENRICO EDUCATION FOUNDATION INC | Henrico | B82 Education | $9.9M | 3 |
| NATIONAL HOSPICE AND PALLIATIVE CARE | Alexandria | P740 Human Services | $9.9M | 10 |
| WORLD PEDIATRICS | Henrico | Q330 International, Foreign Affairs & National Security | $9.9M | 4 |
| THE MEDICAL SOCIETY OF VIRGINIA | Richmond | E112 Health Care | $9.9M | 2 |
| SOUTHERN DOMINION HEALTH SYSTEM | Victoria | — | $9.8M | 5 |
| NATIONAL SOCIETY OF PROFESSIONAL | Alexandria | — | $9.8M | 10 |
| Virginia Health Care Foundation | Richmond | E30B Health Care | $9.8M | 6 |
| AMERICAN HARDWOOD EXPORT COUNCIL | Sterling | S41 Community Improvement & Capacity Building | $9.8M | 2 |
| Norfolk Yacht and Country Club | Norfolk | — | $9.8M | 8 |
| NATIONAL STONE SAND AND GRAVEL | Alexandria | — | $9.8M | 10 |
| Arlington Food Assistance Center | Arlington | K31Z Food, Agriculture & Nutrition | $9.8M | 3 |
| STRATEGIC CAPACITY GROUP INC | McLean | B99 Education | $9.8M | 8 |
| Bill of Rights Institute | Arlington | Z99 Unknown | $9.8M | 11 |
| Care Net | Lansdowne | R62Z Civil Rights, Social Action & Advocacy | $9.7M | 5 |
| NATIONAL AUTOMATIC MERCHANDISING | Arlington | — | $9.7M | 8 |
| CHRISTOPHER NEWPORT UNIVERSITY | Newport News | B110 Education | $9.7M | 5 |
| LITTLE KESWICK EDUCATION | Keswick | B20 Education | $9.7M | 1 |
| CHRISTIAN LIGHT PUBLICATIONS INC | Harrisonburg | X20Z Religion-Related | $9.7M | 2 |
| MARINE CORPS HERITAGE FOUNDATION | Triangle | P20 Human Services | $9.7M | 3 |
| LOCUS IMPACT FUND | Christiansburg | S40 Community Improvement & Capacity Building | $9.7M | 14 |
| ALLIANCE FOR ACADEMIC INTERNAL MEDICINE | Alexandria | B19 Education | $9.6M | 8 |
| AMERICAN FOUNDATION FOR THE BLIND INC | Arlington | P860 Human Services | $9.6M | 10 |
| GUN OWNERS OF AMERICA INC | Springfield | R60 Civil Rights, Social Action & Advocacy | $9.6M | 3 |
| VIRGINIA MARYLAND AND DELAWARE | Glen Allen | — | $9.6M | 22 |
