| Sacramento Steps Forward | Sacramento | P85 Human Services | $38.1M | 7 |
| WEINGART FOUNDATION | Los Angeles | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $38M | 11 |
| BUSINESS FOR SOCIAL RESPONSIBILITY | San Francisco | B82Z Education | $38M | 9 |
| SAN FRANCISCO AIDS FOUNDATION | San Francisco | — | $37.9M | 7 |
| THE ARC OF SAN DIEGO | San Diego | P82Z Human Services | $37.9M | 6 |
| O'CONNOR WOODS HOUSING CORPORATION | Stockton | P750 Human Services | $37.8M | 7 |
| CIVIC SAN DIEGO | San Diego | S31Z Community Improvement & Capacity Building | $37.8M | 5 |
| SANTA BARBARA FOUNDATION | Santa Barbara | T31 Philanthropy, Voluntarism & Grantmaking Foundations | $37.8M | 7 |
| MCALISTER INSTITUTE FOR TREATMENT & | El Cajon | F20Z Mental Health & Crisis Intervention | $37.8M | 3 |
| HILLSIDES | Pasadena | P200 Human Services | $37.7M | 9 |
| SALESFORCE FOUNDATION | San Francisco | B12 Education | $37.7M | 0 |
| GLOBAL SUPPORT AND DEVELOPMENT | Redwood City | P20 Human Services | $37.7M | 2 |
| ANITA BORG INSTITUTE FOR WOMEN AND | San Mateo | U40 Science & Technology | $37.7M | 10 |
| CLIMATE LEAD INC | San Francisco | C19 Environment | $37.5M | 10 |
| ENVIRONMENTAL ALTERNATIVES | Quincy | P32Z Human Services | $37.5M | 4 |
| JAMBOREE HOUSING CORPORATION | Irvine | — | $37.4M | 21 |
| COALITION FOR RESPONSIBLE COMMUNITY | Los Angeles | O50 Youth Development | $37.4M | 4 |
| St Marys Elderly Housing Corporation | Walnut Creek | — | $37.4M | 0 |
| ASIAN PACIFIC HEALTH CARE VENTURE INC | Los Angeles | — | $37.4M | 8 |
| ODD FELLOW- REBEKAH CHILDRENS HOME | Gilroy | — | $37.3M | 11 |
| THE COTTONWOOD SCHOOL | El Dorado Hills | B29 Education | $37.3M | 7 |
| VALUE SCHOOLS | Los Angles | B29 Education | $37.2M | 7 |
| HOBSONLUCAS FAMILY FOUNDATION | San Rafael | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $37.1M | 0 |
| Pathpoint | Santa Barbara | B30 Education | $37.1M | 6 |
| The Rocklin Academy | Rocklin | — | $37M | 7 |
| WATTS HEALTHCARE CORPORATION | Los Angeles | E30 Health Care | $36.9M | 15 |
| CALIFORNIA MONTESSORI PROJECT | Carmichael | B29 Education | $36.9M | 7 |
| GENESIS LA ECONOMIC GROWTH CORPORATION | Los Angeles | S31 Community Improvement & Capacity Building | $36.9M | 5 |
| RINCON DE LOS ESTEROS INC | San Jose | — | $36.9M | 3 |
| 1011 FOUNDATION INC | Santa Monica | — | $36.9M | 0 |
| CALIFORNIA CORRECTIONAL PEACE OFFICERS | West Sacramento | — | $36.8M | 15 |
| SAKANA FOUNDATION | San Francisco | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $36.8M | 0 |
| HELIX CHARTER HIGH SCHOOL | La Mesa | B29 Education | $36.8M | 16 |
| TROPER WOJCICKI FOUNDATION | Los Altos | T22 Philanthropy, Voluntarism & Grantmaking Foundations | $36.8M | 0 |
| COLORADO HEALTH INSURANCE | San Francisco | Y23 Mutual & Membership Benefit | $36.8M | 0 |
| GLOBAL FUND FOR WOMEN INC | San Francisco | Q197 International, Foreign Affairs & National Security | $36.7M | 12 |
| St Anne's Family Services | Los Angeles | P450 Human Services | $36.7M | 8 |
| SAN FRANCISCO UNIVERSITY HIGH SCHOOL | San Francisco | B250 Education | $36.7M | 11 |
| YOSEMITE VALLEY CHARTER SCHOOL | Fresno | B29 Education | $36.6M | 5 |
| CHILDNET YOUTH & FAMILY SERVICES | Long Beach | P300 Human Services | $36.6M | 8 |
| CHILD CARE ALLIANCE OF LOS ANGELES | Los Angeles | P46 Human Services | $36.5M | 6 |
| ALLIANCE FOR SAFETY AND JUSTICE | Oakland | I01 Crime & Legal-Related | $36.5M | 10 |
| ALTURA CENTERS FOR HEALTH | Tulare | E39Z Health Care | $36.4M | 15 |
| SAN DIEGO INTERFAITH HOUSING FOUNDATION | Lemon Grove | — | $36.4M | 1 |
| SUPPORTIVE SERVICES INC | Fresno | P190 Human Services | $36.3M | 5 |
| TECHSOUP GLOBAL | San Francisco | — | $36.2M | 14 |
| Gorman Learning Charter Network | Redlands | B28 Education | $36.2M | 2 |
| ALFREDO AND MARIA BUBION CHARITABLE | Newport Beach | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $36.2M | 0 |
| UNITED SERVICE WORKERS WEST | Los Angeles | — | $36.2M | 69 |
| THE WEBB SCHOOLS | Claremont | B250 Education | $36.2M | 10 |
