| BRIDGES TO PROSPERITY INC | Greenwood Village | Q30 International, Foreign Affairs & National Security | $16.6M | 5 |
| MERCY COMMUNITY CAPITAL | Denver | L20 Housing & Shelter | $16.5M | 8 |
| DENVER SCHOLARSHIP FOUNDATION | Denver | B99 Education | $16.5M | 8 |
| MOORE IMPACT INC | Denver | P20 Human Services | $16.5M | 7 |
| COLORADO MESA UNIVERSITY FOUNDATION | Grand Junciton | B110 Education | $16.4M | 0 |
| GIRL SCOUTS OF COLORADO | Denver | O42 Youth Development | $16.4M | 11 |
| EBEN EZER LUTHERAN CARE CENTER | Brush | E90Z Health Care | $16.4M | 2 |
| INTERNATIONAL ASSOCIATION OF CERTIFIED HOME INSPECTORS | Boulder | S41 Community Improvement & Capacity Building | $16.2M | 11 |
| Thomas MacLaren School | Colorado Springs | B29 Education | $16.2M | 2 |
| MESA DEVELOPMENTAL SERVICES | Grand Junction | P820 Human Services | $16.2M | 2 |
| Classical Education Growth Fund | Golden | B02 Education | $16.1M | 0 |
| Bromley East Charter School | Brighton | B29 Education | $16M | 5 |
| A PRECIOUS CHILD INC | Broomfield | P30 Human Services | $15.9M | 4 |
| United States Fencing Association | Colorado Springs | N71 Recreation & Sports | $15.8M | 8 |
| San Luis Valley Community Mental Health Center | Alamosa | E21 Health Care | $15.8M | 7 |
| UC HEALTH LABORATORY SERVICES | Denver | E80 Health Care | $15.7M | 3 |
| DENVER CHRISTIAN SCHOOLS | Lakewood | B24Z Education | $15.7M | 2 |
| CATHOLIC HEALTH INITIATIVES COLORADO FOUNDATION | Centennial | E110 Health Care | $15.7M | 9 |
| COLORADO ROCKY MOUNTAIN SCHOOL INC | Carbondale | B24Z Education | $15.7M | 6 |
| Mountain Valley Developmental Services | Glenwood Springs | P700 Human Services | $15.5M | 4 |
| UNITED STATES OF AMERICA RUGBY FOOTBALL UNION LTD | Glendale | — | $15.5M | 9 |
| ELEVATION COMMUNITY LAND TRUST | Denver | L21 Housing & Shelter | $15.4M | 8 |
| GAMMA PHI BETA SORORITY INC | Centennial | — | $15.4M | 6 |
| GLOBAL VILLAGE ACADEMY AURORA | Aurora | B29 Education | $15.4M | 0 |
| Colorado Springs Independence Center | Colorado Springs | P800 Human Services | $15.4M | 4 |
| MCREL INTERNATIONAL | Denver | — | $15.4M | 8 |
| BROTHERS BROOK FOUNDATION | Denver | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $15.4M | 0 |
| COLORADO EDUCATION ASSOCIATION | Denver | — | $15.3M | 12 |
| Colorado Laborers Health and Welfare Fund | Aurora | — | $15.3M | 0 |
| STANLEY BRITISH PRIMARY SCHOOL | Denver | B24Z Education | $15.2M | 6 |
| NEIGHBOR TO NEIGHBOR INC | Fort Collins | L800 Housing & Shelter | $15.1M | 2 |
| Community Bible Study | Colorado Springs | X20 Religion-Related | $15.1M | 5 |
| AMG CHARITABLE GIFT FOUNDATION | Greenwood Village | T300 Philanthropy, Voluntarism & Grantmaking Foundations | $15M | 2 |
| Leman Classical School | Parker | B29 Education | $15M | 1 |
| COMFORT BRIDGE DBA CARE SYNERGY | Denver | E02 Health Care | $15M | 11 |
| NATIONAL ENDOWMENT FOR FINANCIAL EDUCATION | Denver | B99 Education | $14.9M | 3 |
| Rocky Mountain Youth Medical and Nursing | Thornton | E99 Health Care | $14.9M | 7 |
| Monument Academy | Monument | B29 Education | $14.9M | 1 |
| MILE HIGH COUNCIL ON ALCOHOLISM AND DRUG ABUSE | Aurora | F21Z Mental Health & Crisis Intervention | $14.9M | 7 |
| Metro Caring | Denver | — | $14.8M | 4 |
| Summit Ministries Inc | Manitou Springs | — | $14.8M | 9 |
| Engineering Ministries International USA | Colorado Springs | U42 Science & Technology | $14.7M | 7 |
| DENVER LANGUAGE SCHOOL | Denver | B20 Education | $14.7M | 5 |
| WESTERN CONSERVATION FOUNDATION | Denver | C30 Environment | $14.6M | 5 |
| WARREN VILLAGE INC | Denver | P42 Human Services | $14.6M | 6 |
| SAVIO HOUSE | Denver | P32 Human Services | $14.5M | 7 |
| Craig Hospital Foundation | Englewood | E22 Health Care | $14.5M | 7 |
| VAIL HEALTH SERVICES FOUNDATION | Vail | E12 Health Care | $14.5M | 2 |
| ENVIRONMENT AMERICA INC | Denver | C30 Environment | $14.4M | 5 |
| Youth for ChristUSA Inc | Englewood | O55Z Youth Development | $14.4M | 7 |
