| CENTERSTONE FOUNDATION | Nashville | F11 Mental Health & Crisis Intervention | $10.7M | 2 |
| KNOWLEDGE ACADEMIES INC | Antioch | B29 Education | $10.6M | 0 |
| TENNESSEE TECHNOLOGICAL UNIVERSITY FOUNDATION | Cookeville | B110 Education | $10.6M | 3 |
| TENNESSEE EDUCATION ASSOCIATION INC | Nashville | — | $10.6M | 9 |
| TENNESSEE VALLEY PUBLIC POWER ASSOC INC | Chattanooga | — | $10.6M | 9 |
| Kappa Delta Foundation Incorporated | Memphis | B820 Education | $10.6M | 2 |
| WELCH COLLEGE | Gallatin | B420 Education | $10.6M | 8 |
| CHAMBLISS CENTER FOR CHILDREN | Chattanooga | — | $10.6M | 8 |
| THE NEXT DOOR INC | Nashville | L41 Housing & Shelter | $10.5M | 3 |
| Kappa Delta Sorority Incorporated | Memphis | — | $10.4M | 11 |
| OUTREACH FOUNDATION OF THE | Franklin | — | $10.4M | 3 |
| NASHVILLE DISTRICT MANAGEMENT CORP INC | Nashville | S20 Community Improvement & Capacity Building | $10.3M | 5 |
| THE COLLEGE AND UNIVERSITY PROFESSIONAL | Knoxville | B034 Education | $10.2M | 6 |
| UNIVERSITY OF TENNESSEE | Knoxville | — | $10.2M | 0 |
| TENNESSEE BAR FOUNDATION | Nashville | I128 Crime & Legal-Related | $10.2M | 1 |
| MEMPHIS JEWISH COMMUNITY CENTER | Memphis | — | $10.2M | 3 |
| SHAOHANNAHS HOPE INC | Franklin | P31 Human Services | $10.1M | 3 |
| LOUISE AND JOHN BRYAN FAMILY FOUNDATION | Nashville | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $10.1M | 0 |
| CHICKASAW COUNTRY CLUB | Memphis | — | $10.1M | 7 |
| Wellmont Wexford House | Johnson City | P810 Human Services | $10M | 14 |
| VERIFIED SOLUTIONS | Memphis | B29 Education | $10M | 3 |
| MERCY MULTIPLIED AMERICA INC | Nashville | — | $9.9M | 5 |
| LIBERTAS SCHOOL OF MEMPHIS | Memphis | B29 Education | $9.9M | 1 |
| OHIO VALLEY CONFERENCE | Brentwood | — | $9.9M | 1 |
| WEST TENNESSEE REGIONAL BLOOD CENTER | Jackson | — | $9.9M | 1 |
| MIDDLE TENNESSEE SCHOOL OF | Madison | B50 Education | $9.9M | 12 |
| SMOKIES LIFE | Gatlinburg | — | $9.8M | 1 |
| HARDEMAN COUNTY COMMUNITY HEALTH CENTER INC | Bolivar | E22Z Health Care | $9.8M | 9 |
| SMOKY MOUNTAIN CHILDREN'S HOME | Sevierville | P70 Human Services | $9.8M | 1 |
| PLUMBERS & STEAMFITTERS UNION LOCAL | Goodlettsville | — | $9.8M | 0 |
| THE CLAYTON FAMILY FOUNDATION | Knoxville | — | $9.7M | 0 |
| NASHVILLE WIRE PRODUCTS COMPANY RESTATED | Nashville | — | $9.7M | 1 |
| HOOSIER CHRISTIAN VILLAGE | Nashville | — | $9.7M | 4 |
| Alpha Omicron Pi Properties Inc | Brentwood | — | $9.7M | 0 |
| Emerald Spring Hill Inc | Nashville | — | $9.6M | 6 |
| COLLABORATIVE COMPOSITE SOLUTIONS | Knoxville | P20 Human Services | $9.6M | 3 |
| TRINITY CHRISTIAN ACADEMY INC | Jackson | B24Z Education | $9.6M | 0 |
| GASTROINTESTINAL SPECIALISTS | Memphis | E21 Health Care | $9.6M | 13 |
| JACKSON CHRISTIAN SCHOOL | Jackson | B24Z Education | $9.5M | 0 |
| Chi Omega Fraternity | Memphis | — | $9.5M | 3 |
| Dawn of Hope Inc | Johnson City | P820 Human Services | $9.4M | 1 |
| AHS OF GREATER MEMPHIS FOUNDATION INC | Memphis | — | $9.4M | 4 |
| BRIGHT SCHOOL INC | Chattanooga | B21Z Education | $9.4M | 1 |
| MOUNTAIN CITY CLUB | Chattanooga | — | $9.4M | 2 |
| FAIRVIEW HOUSING MANAGEMENT CORP | Johnson City | L80Z Housing & Shelter | $9.4M | 1 |
| EMERALD YOUTH FOUNDATION | Knoxville | O50Z Youth Development | $9.4M | 1 |
| THE ELEPHANT SANCTUARY IN TENNESSEE | Hohenwald | D310 Animal-Related | $9.4M | 3 |
| PLUMBERS & STEAMFITTERS LOCAL 150 | Goodlettsville | — | $9.4M | 0 |
| WORKFORCE ESSENTIALS INC | Clarksville | J200 Employment | $9.3M | 1 |
| GILLILAND FAMILY FUND INC | Memphis | T112 Philanthropy, Voluntarism & Grantmaking Foundations | $9.3M | 4 |
