| AMPLA HEALTH | Yuba City | E39Z Health Care | $107.1M | 12 |
| NATIONAL ACADEMY OF RECORDING ARTS & | Santa Monica | — | $107.1M | 10 |
| CALIFORNIA ONLINE PUBLIC SCHOOLS | San Juan Capistrano | B29 Education | $106M | 7 |
| HEBREW HOME FOR AGED DISABLED | San Francisco | P750 Human Services | $105.8M | 13 |
| ADVOCACY ACTION FUND INC | Menlo Park | T01 Philanthropy, Voluntarism & Grantmaking Foundations | $105.7M | 5 |
| SOUTHERN CALIFORNIA DRUG BENEFIT FUND | Los Angeles | — | $105.1M | 2 |
| KLAMATH RIVER RENEWAL CORPORATION | Berkeley | C32 Environment | $104.8M | 4 |
| SEIU LOCAL 2015 | Los Angeles | — | $104.8M | 144 |
| VISIONS IN EDUCATION | Carmichael | B29 Education | $104.7M | 17 |
| Daffy Charitable Fund | Los Altos | T30 Philanthropy, Voluntarism & Grantmaking Foundations | $104.4M | 0 |
| CALIFORNIA FIELD IRON WORKER VACATION | Pasadena | — | $104.1M | 0 |
| SAN FRANCISCO OPERA ASSOCIATION | San Francisco | A6A0 Arts, Culture & Humanities | $103.9M | 14 |
| SYSTEM MANAGEMENT GROUP | San Diego | B12 Education | $103.8M | 17 |
| CLINICAS DE SALUD DEL PUEBLO INC | El Centro | E30Z Health Care | $103.7M | 9 |
| WELLNESS WORX INC | Oxnard | E19 Health Care | $103.7M | 0 |
| COMMON COUNSEL FOUNDATION | Oakland | S50 Community Improvement & Capacity Building | $102.1M | 13 |
| CAL POLY POMONA FOUNDATION INC | Pomona | B110 Education | $102M | 21 |
| WEINGART CENTER ASSOCIATION | Los Angeles | L410 Housing & Shelter | $101.9M | 5 |
| ENLIGHT FOUNDATION | Palo Alto | T20 Philanthropy, Voluntarism & Grantmaking Foundations | $101.7M | 1 |
| Sheet Metal Workers' Health Plan of | Manhattan Beach | — | $101.5M | 0 |
| UNIVERSITY OF CALIFORNIA | Irvine | B110 Education | $101.1M | 5 |
| GRANADA HILLS CHARTER | Granada Hills | B29 Education | $101M | 28 |
| EL PROYECTO DEL BARRIO INC | Arleta | P280 Human Services | $101M | 12 |
| CHARLES R DREW UNIVERSITY OF MEDICINE | Los Angeles | B54Z Education | $100.6M | 19 |
| Goodwill Industries Sacramento Valley & | Sacramento | J32Z Employment | $100.4M | 13 |
| FIRST ENTERTAINMENT CREDIT UNION | Hollywood | — | $100.3M | 13 |
| KAISER PERMANENTE BERNARD J TYSON SCHOOL | Oakland | B50 Education | $100.3M | 26 |
| AMALGAMATED TRANSIT UNION-DIV 1277 SCRTD | Los Angeles | — | $99.8M | 0 |
| HOLLYWOOD FOREIGN PRESS ASSOCIATION | West Hollywood | T90Z Philanthropy, Voluntarism & Grantmaking Foundations | $99.5M | 21 |
| FARMLINK PROJECT | Los Angeles | P20 Human Services | $99.3M | 5 |
| NATIONAL HOT ROD ASSOCIATION | San Dimas | — | $99.2M | 13 |
| MENTAL HEALTH SYSTEMS INC | San Diego | F300 Mental Health & Crisis Intervention | $99.1M | 6 |
| NORTHBAY HEALTHCARE CORPORATION | Fairfield | E210 Health Care | $98.7M | 18 |
| BAY AREA COMMUNITY SERVICES INC | Oakland | — | $98.3M | 0 |
| GOODWILL INDUSTRIES OF SAN DIEGO COUNTY | San Diego | J320 Employment | $97.7M | 8 |
| HIGH TECH HIGH | San Diego | B25 Education | $97.4M | 10 |
| CALIFORNIA SCHOOL EMPLOYEES ASSOCIATION | San Jose | — | $97.1M | 26 |
| CENTRAL CALIFORNIA FOOD BANK | Fresno | K310 Food, Agriculture & Nutrition | $96.9M | 3 |
| CARES Community Health | Sacramento | G81Z Diseases, Disorders & Medical Disciplines | $96.8M | 13 |
| THE HEARTHLAND FOUNDATION | Los Angeles | — | $96.8M | 0 |
| Willits Hospital Inc | Willits | O40Z Youth Development | $96.7M | 25 |
| THE SAN DIEGO SYMPHONY ORCHESTRA | San Diego | A690 Arts, Culture & Humanities | $96.5M | 8 |
| COMMUNITY RESEARCH FOUNDATION INC | San Diego | Z99Z Unknown | $96.3M | 14 |
| Casa Colina Hospital and Centers for Healthcare | Pomona | E24 Health Care | $96.2M | 12 |
| UNITED STATES VETERANS INITIATIVE | Los Angeles | P50Z Human Services | $96M | 13 |
| ASPIRANET | South San Francisco | P32Z Human Services | $95.9M | 13 |
| ROESSLER-CHADWICK FOUNDATION | Palos Verdes Peninsula | B200 Education | $95.8M | 14 |
| Teamsters Local 1932 Health and Welfare Trust | San Bernardino | — | $95.2M | 0 |
| GO KIDS INC | Gilroy | P34Z Human Services | $95.2M | 5 |
| VANGUARD UNIVERSITY OF SO CAL | Costa Mesa | B420 Education | $94.8M | 10 |
