| Food Bank of Alaska | Anchorage | K31Z Food, Agriculture & Nutrition | $21.7M | 6 |
| BRISTOL BAY ECONOMIC DEVELOPMENT CORP | Dillingham | — | $20M | 23 |
| AFOGNAK NATIVE CORPORATION FRINGE BENEFIT TRUST | Anchorage | Y43 Mutual & Membership Benefit | $18.9M | 4 |
| Ilisagvik College | Barrow | B41Z Education | $18.1M | 21 |
| CENTRAL BERING SEA FISHERMEN'S ASSOCIATION | St Paul Island | — | $17.8M | 16 |
| Peninsula Community Health Services of Alaska | Soldotna | E30 Health Care | $17.8M | 11 |
| PROVIDENCE ALASKA FOUNDATION | Anchorage | E21I Health Care | $17.4M | 2 |
| Eastern Aleutian Tribes Inc | Anchorage | B99Z Education | $16.4M | 23 |
| Anchorage Neighborhood Housing Services Inc | Anchorage | L25 Housing & Shelter | $16.2M | 5 |
| VALLEY CHARITIES INC | Wasilla | Z99Z Unknown | $16.1M | 3 |
| ANCHORAGE CONVENTION & VISITORS BUREAU DBA VISIT ANCHORAGE | Anchorage | — | $16M | 5 |
| Southern Southeast Regional Aquaculture | Ketchikan | D330 Animal-Related | $15.2M | 15 |
| COVENANT HOUSE ALASKA | Anchorage | P300 Human Services | $15M | 8 |
| FAMILY CENTERED SERVICES OF ALASKA | Fairbanks | P820 Human Services | $14.6M | 7 |
| No on 2 | Anchorage | — | $14.5M | 2 |
| INTERNATIONAL BROTHERHOOD OF ELECTRICAL WORKERS | Anchorage | — | $14.3M | 14 |
| Set Free Alaska Inc | Wasilla | F220 Mental Health & Crisis Intervention | $14M | 5 |
| NUSHAGAK ELECTRIC & TELEPHONE COOPERATIVE INC | Dillingham | Y22 Mutual & Membership Benefit | $13.8M | 8 |
| The Arc of Anchorage | Anchorage | — | $13.7M | 5 |
| True North Recovery Inc | Wasilla | E99 Health Care | $13.7M | 12 |
| Assets Inc | Anchorage | J200 Employment | $13.4M | 5 |
| JUNEAU ECONOMIC DEVELOPMENT COUNCIL | Juneau | — | $13.4M | 1 |
| PRINCE WILLIAM SOUND AQUACULTURE CORPORATION | Cordova | — | $13.3M | 9 |
| Community Connections Inc | Ketchikan | P82Z Human Services | $13.3M | 1 |
| NAKNEK ELECTRIC ASSOCIATION INC | Naknek | — | $12.9M | 13 |
| Blood Bank of Alaska Inc | Anchorage | E61Z Health Care | $12.8M | 6 |
| Denali Family Services | Anchorage | F99Z Mental Health & Crisis Intervention | $12.8M | 4 |
| Anchorage Museum Association | Anchorage | A54 Arts, Culture & Humanities | $12.7M | 7 |
| Aleutian Pribilof Island Community Development Association APICDA | Juneau | P20Z Human Services | $12.5M | 20 |
| ALASKA CHILDREN'S SERVICES INC | Anchorage | F330 Mental Health & Crisis Intervention | $12.2M | 4 |
| SUNSHINE COMMUNITY HEALTH CENTER INC | Talkeetna | E32Z Health Care | $12.2M | 8 |
| SEWARD ASSOCIATION FOR THE ADVANCEMENT OF MARINE SCIENCE | Seward | D110 Animal-Related | $12M | 4 |
| FAIRBANKS RESOURCE AGENCY | Fairbanks | P8XZ Human Services | $12M | 4 |
| Mat-Su Health Services Inc | Wasilla | F30Z Mental Health & Crisis Intervention | $12M | 11 |
| PRESBYTERIAN HOSPITALITY HOUSE INC | Fairbanks | F33Z Mental Health & Crisis Intervention | $12M | 2 |
| REACH INC | Juneau | — | $11.4M | 7 |
| ALASKA CENTER FOR THE PERFORMING ARTS | Anchorage | A610 Arts, Culture & Humanities | $11.3M | 1 |
| SOUTHEAST REGIONAL RESOURCE CENTER | Juneau | B020 Education | $11.3M | 4 |
| Alaska Native Heritage Center Inc | Anchorage | A230 Arts, Culture & Humanities | $11M | 3 |
| Fountainhead Museum Foundation | Fairbanks | A54 Arts, Culture & Humanities | $10.6M | 0 |
| NORTHERN SOUTHEAST REGIONAL AQUACULTURE ASSOCIATION INC | Sitka | D330 Animal-Related | $10.6M | 15 |
| FAIRBANKS COMMUNITY FOOD BANK SERVICE INC | Fairbanks | K31 Food, Agriculture & Nutrition | $10.5M | 2 |
| ALASKA FEDERATION OF NATIVES | Anchorage | — | $10.4M | 5 |
| UNITED WAY OF ANCHORAGE | Anchorage | T700 Philanthropy, Voluntarism & Grantmaking Foundations | $10.2M | 5 |
| ALASKA STATE FAIR INC | Palmer | N520 Recreation & Sports | $10.1M | 11 |
| JAMHI HEALTH & WELLNESS INC | Juneau | F700 Mental Health & Crisis Intervention | $10M | 4 |
| International Brotherhood of Teamsters | Anchorage | — | $9.9M | 12 |
| Alaska Travel Industry Association Incorporated | Anchorage | — | $9.8M | 1 |
| NATIVE MOVEMENT | Fairbanks | S20 Community Improvement & Capacity Building | $9.7M | 8 |
| KOTZEBUE ELECTRIC ASSOCIATION INC | Kotzebue | — | $9.6M | 14 |
